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BBSRC - Biotechnology and Biological Sciences Research Council (BBSRC) - Home

BBSRC - Biotechnology and Biological Sciences Research Council (BBSRC) - Home
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Centre for Synthetic Biology and Innovation The Centre for Synthetic Biology and Innovation (CSynBI) is developing the foundational tools for synthetic biology and using these to generate innovative biological applications for cutting-edge research, healthcare and industry. Along with our research and development of synthetic biology we also integrate our science with emerging ethical, legal and societal issues to responsibly mature this powerful new technology. The research laboratories of CSynBI opened in April 2010 and have already produced many exciting publications in synthetic biology. CSynBI is comprised of scientific researchers at Imperial College London and societal and ethical researchers from the Department of Social Science, Health and Medicine at King's College London. Synthetic Immune System: an artwork for the EPSRC Impact!

London Medicine The Institute of Biomedical Science (IBMS) Genomes of 201 microbes sequenced 15 July 2013Last updated at 09:09 GMT By Rebecca Morelle Science reporter, BBC World Service Microbes that can thrive in extreme environments - but are tricky to grow in the laboratory The genetic secrets of some of the most abundant and diverse forms of life on Earth have been uncovered by scientists. Researchers have sequenced the genomes of 201 microbes to find out more about the role these tiny, single-celled organisms play in our environment. This insight into the genetic code has also helped the team to draw up a more detailed version of the microbial family tree. The work is published in Nature. Phil Hugenholtz, director of the Australian Centre for Ecogenomics at the University of Queensland, in Australia, said: "For almost 20 years now we have been astonished by how little there is known about massive regions of the tree of life. "For me, taxonomic assignment is important as it welcomes in strangers and makes them part of the family. Nature's survivors Continue reading the main story

Biotechnologist job profile If you have an inquisitive mind with an interest in using live organisms to help solve society's problems, then a career as a biotechnologist could be for you Biotechnologists use biological organisms to develop or make products designed to improve health, food and the world around us. They study the genetic, chemical and physical attributes of cells, tissues and organisms and identify practical uses for this knowledge to aid medical, pharmaceutical, agricultural, or environmental advancement to essentially improve the quality of human life. The work involves manipulating living organisms or their components to design or enhance vaccines, medicines, energy efficiency or food productivity. In the last decade, the growth of UK biotechnology has been phenomenal. Large biotechnology companies tend to use the term biotechnologist as a job title. Types of biotechnologist Types of biotechnology include: You would usually specialise in one area of biotechnology, such as: Responsibilities Salary Skills - internationalising UK Life Sciences Draft DIYbio Code of Ethics from European Congress Transparency Emphasize transparency and the sharing of ideas, knowledge, data and results. Safety Adopt safe practices. Open Access Promote citizen science and decentralized access to biotechnology. Education Help educate the public about biotechnology, its benefits and implications. Modesty Know you don’t know everything. Community Carefully listen to any concerns and questions and respond honestly. Peaceful Purposes Biotechnology must only be used for peaceful purposes. Respect Respect humans and all living systems. Responsibility Recognize the complexity and dynamics of living systems and our responsibility towards them. Accountability Remain accountable for your actions and for upholding this code. History: This draft code of ethics was drafted by individuals participating in the 2011 European DIYbio Congress.

The British In Vitro Diagnostics Association (BIVDA) UK government backs three-person IVF 27 June 2013Last updated at 19:33 ET By James Gallagher Health and science reporter, BBC News Opponents fear that other forms of genetic modifications could follow The UK looks set to become the first country to allow the creation of babies using DNA from three people, after the government backed the IVF technique. It will produce draft regulations later this year and the procedure could be offered within two years. Experts say three-person IVF could eliminate debilitating and potentially fatal mitochondrial diseases that are passed on from mother to child. Opponents say it is unethical and could set the UK on a "slippery slope". They also argue that affected couples could adopt or use egg donors instead. Mitochondria are the tiny, biological "power stations" that give the body energy. Defective mitochondria affect one in every 6,500 babies. Continue reading the main story The woman who lost all her children Every time Sharon Bernardi became pregnant, she hoped for a healthy child.

Transgenic Goats Producing Human Breast Milk Enzyme May Help Stop GI Infections Wordwide (w/video) 0inShare Researchers from University of California Davis have reported in PLOS ONE the development of transgenic goats that produce lysozyme, an antimicrobial normally found in human breast milk. The idea is to use the milk to prevent or alleviate the effects of gastrointestinal infections. James (Jim) Murray, UC Davis professor of animal science and vet med population health and reproduction, photographed at the Dairy Goat Research Facility on campus. The team then setup an experiment where two groups of pigs infected with E. coli were fed from the new, and from the boring old goat’s milk. More from PLOS ONE: The CBC analysis showed circulating monocytes (p = 0.0413), neutrophils (p = 0.0219), and lymphocytes (p = 0.0222) returned faster to pre-infection proportions in hLZ-milk fed pigs, while control-fed pigs had significantly higher hematocrit (p = 0.027), indicating continuing dehydration.

New Coating Makes Silicon Circuits Implantable in Human Tissue 9inShare A silicon circuit, coated with a protective layer and immersed in fluid that mimicks human body chemistry. Photo courtesy of Ohio State University. Biosensors and implantable medical devices of the future will have to live in a climate that’s hostile to traditional silicon-based electronic circuits. Researchers at Ohio State University have demonstrated a new coating made of aluminum oxide that can encapsulate silicon circuits to keep them dry from the electrolytes in bodily fluids. More from Ohio state about the motivations for the research: The project began when Berger talked to researchers in Ohio State’s Department of Biomedical Engineering, who wanted to build an insertable sensor to detect the presence of proteins that mark the first signs of organ rejection in the body. Paper in Electronics Letters: Towards in vivo biosensors for low-cost protein sensing Ohio State: The Body Electric: Researchers Move Closer to Low-Cost, Implantable Electronics

Surgeons at Duke University Hospital Implant Bioengineered Vein By Duke Medicine News and Communications Kidney dialysis patient first in U.S. to receive blood vessel grown in laboratory DURHAM, N.C. – In a first-of-its-kind operation in the United States, a team of doctors at Duke University Hospital helped create a bioengineered blood vessel and transplanted it into the arm of a patient with end-stage kidney disease. The procedure, the first U.S. clinical trial to test the safety and effectiveness of the bioengineered blood vessel, is a milestone in the field of tissue engineering. The new vein is an off-the-shelf, human cell-based product with no biological properties that would cause organ rejection. the technology and performed the implantation. rejection; they become indistinguishable from living tissue as cells grow into the implant.

World's first lab-grown burger to be cooked and eaten 4 August 2013Last updated at 22:31 ET By Pallab Ghosh Science correspondent, BBC News Professor Mark Post of Maastricht University explains how he and his colleagues made the world's first lab-grown burger The world's first lab-grown burger is to be unveiled and eaten at a news conference in London on Monday. Scientists took cells from a cow and, at an institute in the Netherlands, turned them into strips of muscle which they combined to make a patty. Researchers say the technology could be a sustainable way of meeting what they say is a growing demand for meat. Critics say that eating less meat would be an easier way to tackle predicted food shortages. BBC News has been granted exclusive access to the laboratory where the meat was grown in a project costing £215,000. Prof Mark Post of Maastricht University, the scientist behind the burger, said: "Later today we are going to present the world's first hamburger made in a lab from cells. "That's just weird and unacceptable. “Start Quote