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A molecular link between the active component of m... [Mol Pharm. 2006 Nov-Dec] - PubMed result

A molecular link between the active component of m... [Mol Pharm. 2006 Nov-Dec] - PubMed result

Finally, a fat-fighting drug that shows promise - health - 07 January 2011 Hands up everyone whose new year's resolution is to lose weight. Wouldn't it be great if we could just take a pill to shed fat? Time and again "diet pills" have turned out to be useless, dangerous or both – but now there may finally be a safe one that works. Zafgen, a start-up drug company in Cambridge, Massachusetts, has announced that its first human test of a drug named ZGN-433 caused 24 obese women to lose, on average, a kilogram a week for a month – with no harmful side effects. The trial could not be extended past a month without initial safety tests at a range of doses – which was the purpose of this trial. This is a stunning rate of weight loss, especially as the women ate normally and were not given exercise advice. . Fat makes you fatter It isn't all your fault that it is so hard to lose weight. In particular, fat makes you lose sensitivity to the hormone insulin, which normally promotes the burning of fat and opposes its synthesis. More From New Scientist Promoted Stories

printer Eating 10 hot dogs in 6 minutes and belching the national anthem may impress your friends, but neither of those feats will do much for your body—at least not much good. Instead, why not train yourself to do something that may actually pay off? We're not talking bench presses and interval training (though those do help). You can teach your body to cure itself from everyday health ailments—side stitches, first-date jitters, even hands that have fallen asleep. Just study this list, and the next time your friends challenge you to an ice cream eating contest, chow down: You know how to thaw a brain freeze—and 17 other tricks that'll make everyone think you're the next David Blaine. Do Them Right: To mazimize your workout, good form is a must. Cure a Tickling Throat When you were 9, playing your armpit was a cool trick. Experience Supersonic Hearing If you're stuck chatting up a mumbler at a cocktail party, lean in with your right ear. Overcome Your Most Primal Urge Need to pee? Feel No Pain

Lose weight the French way Attack phase ... Protein like meat and fish is the focus of the first stage of the Dukan Diet. Source: The Sunday Telegraph HAVE you ever wondered why most French women appear to be effortlessly slim? When French nutritionist Dr Pierre Dukan introduced his Dukan Diet there 10 years ago, the book rushed to the top of the French bestseller list and spawned a dieting revolution. Today, more than 1.5 million French women swear by its dramatic and long-lasting results. Politicians, film stars and high-profile models, including Gisele Bündchen and Jennifer Lopez, live the Dukan life, all of them seduced by its promise of permanent slenderness while eating what you like. The basic rules The Dukan Diet starts with a short Attack phase, where you eat nothing but protein – just meat, fish, eggs and non-fat dairy products. This is the kick-start that gives you the initial impetus and sets the tone for the other phases. After one to 10 days in the Attack phase, dieters move on to the Cruise phase.

WHAT DO PHILOSOPHERS BELIEVE? The Visual CV: in a career spanning half a century, Sir Tom Courtenay has gone from a new-wave warrior to a grand old man, via a fool or two (usually called Norman). Irving Wardle picks his best roles on stage and screen From INTELLIGENT LIFE magazine, January/February 2013 1960 The SeagullArriving on the London stage as a RADA graduate from the fish docks of Hull, Tom Courtenay achieved overnight fame as Chekhov’s Konstantin. 1962 The Loneliness of the Long-Distance Runner1963 Billy LiarAlways most at home on the stage, Courtenay went on to consolidate his reputation with three films. 1965 Dr Zhivago (right) In David Lean’s Pasternak adaptation Courtenay resumed his Russian persona as Pasha Antipov. 1974 The Norman ConquestsAfter Billy Liar, Courtenay was inescapable casting for the anarchic assistant librarian hero of Alan Ayckbourn’s family reunion trilogy. Quartet now showing in Britain

Top 6 Sites that Inspire and Educate & Life Scoop - StumbleUpon If you’re a professional who likes to be intellectually stimulated and you enjoy keeping up with the latest news and breaking trends, the internet provides you with an endless choice of carefully curated sites to visit. Today, we bring you six of them that we believe are leaps and bounds above the rest. These sites will not only educate you on topics ranging from business and technology to art and design, they’ll motivate you to find your own, original ideas and see them through. They’re culturally relevant, they’re idea driven and most of all, they’re deeply inspirational. TED is short for three incredibly important subjects in our modern world; technology, entertainment and design. Started in 1984, TED brings together the most brilliant minds to teach us about issues that matter. Tip: Download TED’s free iPad app to browse through 800 videos by date, popularity or keyword. 2. Brain Pickings started from very humble beginnings. 4. 5.

Anadenanthera peregrina "Ebene" redirects here. For the city in Mauritius, see Ebene City. Anadenanthera peregrina, also known as Yopo, Jopo, Cohoba, Parica or Calcium Tree, is a perennial tree of the Anadenanthera genus native to the Caribbean and South America.[1] It grows up to 20 m tall, having a horny bark. Its flowers are pale yellow to white and spherical. It is not listed as being a threatened species. It is an entheogen used in healing ceremonies and rituals. Related species[edit] This plant is almost identical to that of a related tree, Anadenanthera colubrina, commonly known as Cebíl or Vilca. Botanical varieties[edit] Uses[edit] Traditional medicine[edit] Know in some urban cultures as a cheap way to get a high. Wood[edit] The wood from A. peregrina is very hard and it is good for making furniture.[2] It has a Janka rating of 3700 lb.[3] and a density of around 0.86 g/cm³.[4] Toxicity[edit] The beans (sometimes called seeds) and falling leaves are hallucinogenic and are toxic to cattle.[5] Modern yopo snuff

Did you know There is no hiding with LSD | Sue Blackmore Is LSD a great spiritual teacher? Or indeed a teacher at all? My answer is an emphatic "Yes", even though there will always be students who learn nothing from their teachers or misuse what they do learn. For me LSD is the ultimate psychedelic. It's a tough one – one not to be taken lightly or often. A typical trip lasts eight to 10 hours and there's no respite or way out once you've popped that tiny scrap of blotter in your mouth. So why do it? That experience, as many writers have explained, depends dramatically on the set and setting – on what you expect of the trip, where you are, whom you are with, and how safe you feel. Of course the psychedelics can be just plain fun – the amazing colours, the shifting and moving scenes, the flowers that turn into cats that turn into rabbits that disappear down holes; the sounds that turn into streams that flow away into the sky. For myself I used to face terrible scenes of torture, rape and other kinds of human cruelty.

Green Lake - An Austrian Lake That Is Used for Hiking A rare natural phenomenon turns one of Austria’s most beautiful hiking trails into a 10 meter-deep lake, for half the year. Located at the foot of the Hochschwab Mountains, in Tragoess, Styria, Green Lake is one of the most bizarre natural phenomena in the world. During the cold winter months, this place is almost completely dry, and used as a country park where hikers love to come and spend some time away from urban chaos. But as soon as temperatures rise, the snow and ice covering the mountaintops begin to melt, and the water pours down, filling the basin below with crystal-clear water. Water levels go from one-two meters at most, to over 10 meters, in the early summer. The waters of Green Lake are highest in June, when this extraordinary place is invaded by divers, curious to see what a mountain park looks like underwater. Take a look at the amazing images of the Green Lake, shot during the summer season: via Daily Mail Reddit Stumble

World Digital Library Home Colbert's Best Marijuana Moments | Comedy Central Insider | Funny, TV and Comedy Blog Click here to watch Jon Stewart discuss Kansas’s anti-gay legislation on The Daily Show. Click here to watch Nathan help a hotdog stand, or we’ll have to teach you a lesson. Click here to watch Stephen Colbert celebrate Women’s History Month. Click here to watch Jon Stewart discuss the child immigration debate. Click here to say “aloha” to the Hawaii episode of Drunk History. Brain Fitness And Memory Programs, Brain Training - CogniFit

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