Scientists Identify Gene Required for Nerve Regeneration
A gene that is associated with regeneration of injured nerve cells has been identified by a team of researchers led by Prof Melissa Rolls of Penn State University. In fruit flies with two normal copies of the spastin gene, a team of scientists led by Prof Melissa Rolls of Penn State University found that severed axons were able to regenerate. However, in fruit flies with two or even only one abnormal spastin gene, the severed axons were not able to regenerate (Melissa Rolls / Penn State University) The team has found that a mutation in a single gene can entirely shut down the process by which axons – the parts of the nerve cell that are responsible for sending signals to other cells – regrow themselves after being cut or damaged. “We are hopeful that this discovery will open the door to new research related to spinal-cord and other neurological disorders in humans,” said Prof Rolls, who co-authored a paper published online in the journal Cell Reports.
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