Oocyte activation Oocyte (or ovum/egg) activation is a series of processes that occur in the oocyte during fertilization. Sperm entry causes calcium release into the oocyte. In mammals, this has been proposed to be caused by the introduction of phospholipase C isoform zeta (PLCζ) from the sperm cytoplasm, although this remains to be established definitively. Activation of the ovum includes the following events: Cortical reaction to block against other sperm cellsActivation of egg metabolismReactivation of meiosisDNA synthesis
UK Stem Cell Bank - Our research - Medical Research Council Funded by the MRC and Biotechnology and Biological Sciences Research Council, the UK Stem Cell Bank was established to provide an ethically approved, quality controlled and assured repository of human embryonic, fetal and adult stem cell lines to underpin high quality research and healthcare developments. Located at the National Institute for Biological Standards and Control (NIBSC), resources are available to both national and international researchers. Background
MayoClinic.com Health Library - Fetal development: The first trimester You're pregnant. Congratulations! You'll undoubtedly spend the months ahead wondering how your baby is growing and developing. What does your baby look like? How an embryo turns into a baby, in one hypnotic GIF You were once a single-celled zygote — a microscopic blob of tissue. But over the course of nine months or so, you developed into a breathing, eating, crying baby. This process really is one of the most extraordinary in all of nature. And this beautiful GIF, created by designer Eleanor Lutz for her blog Tabletop Whale, provides a hypnotic look at this transformation. (Eleanor Lutz) Watch a single embryo move through the spiral over time.
Embryonic stem cell research: an ethical dilemma A human embryo can split into twins or triplets until about 14 days after fertilization Egg and sperm: some people believe an embryo must be fully protected from conception onwards (Wellcome Images/Spike Walker) Human blastocyst on the tip of a pin: embryonic stem cells can be grown from cells found in the blastocyst (Wellcome Images/Yorgos Nikas) Some people think an embryo deserves special protection from about 14 days after fertilization Pregnancy and Human Development Pregnancy and Human Development From Egg to Zygote Pregnancy - events from fertizilation until birth. Conceptus - the developing offspring. Gestation period - from the last menstrual period until birth.
American Bioethics Advisory Commission The Moral Status of the Human Embryo according to Peter Singer: Individuality, Humanity, and Personhood By Fr. Joseph Howard American Life League Peter Singer is a prominent Australian philosopher currently at Princeton University who many might consider to hold radical views on human life. Singer argues that the early human embryo is not a human individual who is a person. He contends that the 'potential' of a human embryo existing in the laboratory is not the same as the one who is already implanted in the endometrium of the uterus.
What is "Bioethics"?? pg.4 D. The problem of "personhood": Although bioethics conveniently wants desperately to claim that it does not embody any anthropology - or definition of a "person" - it obviously does. As noted (and referenced above and below), many (if not most) of those who heavily influenced the development of bioethics brought to their several analyses very specific positions on "personhood" -- especially the "personhood" of the early human embryo and the human fetus.
Key Ethical Issues in Embryonic Stem Cell Research IntroductionThe Basic Ethical ProblemEvaluating the Benefits of Embryonic Stem Cell Research De-sensitisation to the Destruction of Human Life Contributions to Social Oppression The Value of the Embryo Embryos Created for Research Purposes? Jeffrey M. Smith Biography The leading consumer advocate promoting healthier non-GMO choices, Jeffrey Smith's meticulous research documents how biotech companies continue to mislead legislators and safety officials to put the health of society at risk and the environment in peril. His work expertly summarizes why the safety assessments conducted by the FDA and regulators worldwide teeter on a foundation of outdated science and false assumptions, and why genetically engineered foods must urgently become our nation's top food safety priority. Mr. Smith’s feature-length documentary Genetic Roulette — The Gamble of Our Lives was awarded the 2012 Movie of the Year (Solari Report) and the Transformational Film of the Year (AwareGuide).
virtual philosopher: Julian Savulescu discussing Craig Venter's synthetic bacterium Craig Venter has created a synthetic bacterium in the laboratory (there are many links about this on the Nature blog). What are the implications of this breakthrough? I asked Julian Savulescu, Director of Oxford University's Uehiro Centre for Practical Ethics. Click on the button below to listen to the interview which is 11 minutes 16 seconds long. It may take a few seconds before it starts to play. Julian Savulescu on Craig Venter's synthetic bacterium
Patent Rights in Biological Material Greenberg et al. v. Miami Children’s Hospital Research Institute et al. In 2003, a Florida District Court revisited the issues raised in the Moore case in Greenberg et al. v. Miami Children’s Hospital Research Institute et al. In this case, a group of individuals and nonprofit institutions involved in research on Canavan disease (Greenberg group) entered into a collaboration with Reuben Matalon, M.D., and the Miami Children’s Hospital Research Institute (MCH) to identify the gene responsible for Canavan disease. The individual members of the Greenberg group, who were parents of children afflicted with Canavan disease, collected blood and tissue samples from Canavan families and supplied these to Dr.
Horizon 2020: EU funding of hESC research in the balance Prof. Aurora Plomer Stem cell research has the potential to bring important advances in our understanding and treatment of crippling diseases such as Parkinson’s, diabetes, stroke and heart disease. It has also attracted significant investment in a number of countries in Europe, notably the UK and Germany, which have established themselves as global market leaders in stem cell therapy and technology. The amount allocated to stem cell research under previous EU programmes has formed a relatively small portion of the overall budget but played a vital role in facilitating collaborations amongst EU researchers which would not have been possible through national funding alone. Yet, the funding of embryonic stem cell research in Europe now lies in the balance.