News Bulletin of International HoloGenomics Society
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UniProtKB/TrEMBL Release Statistics
UniProtKB/TrEMBL PROTEIN DATABASE RELEASE 2014_04 STATISTICS 1. INTRODUCTION Release 2014_04 of 16-Apr-2014 of UniProtKB/TrEMBL contains 54958551 sequence entries, comprising 17473872940 amino acids. 759560 sequences have been added since release 2014_03, the sequence data of 13762 existing entries has been updated and the annotations of 16654879 entries have been revised. This represents an increase of 2%. Number of fragments: 5207483 Protein existence (PE): entries % 1: Evidence at protein level 22220 0.04% 2: Evidence at transcript level 856181 1.56% 3: Inferred from homology 13964112 25.41% 4: Predicted 40116038 72.99% 5: Uncertain 0 0.00% The growth of the database is summarized below. 2.
Patent EP2525649A2 - Excision of transgenes in genetically modified organisms - Google Patents
This application claims the benefit of U.S. Provisional Patent Application Serial No. 61/297,628, filed January 22, 2010, titled "Excision of Transgenes in Genetically Modified Organisms." The invention generally relates to compositions and methods for generating transgenic plants. In certain embodiments, the transgenic plants comprise one or more transgenes of interest. In certain embodiments, excision of trans gene(s) is directed in pollen and/or seed, such that the pollen and/or seed produced by a transgenic plant of the invention is substantially free of transgene(s). In some embodiments, transgenic plants of the invention are useful, for example, in achieving bioconfinement of trans gene(s) of interest in the transgenic plant.
Smarter Than Us
What happens when machines become smarter than humans? Forget lumbering Terminators. The power of an artificial intelligence (AI) comes from its intelligence, not physical strength and laser guns. Humans steer the future not because we’re the strongest or the fastest but because we’re the smartest.
DNA Stores MLK's Speech, Shakespeare's Sonnets
A team of scientists in the U.K. has encoded text, sound files and a photograph onto strings of DNA, and successfully retrieved it without errors. Nick Goldman and Ewan Birney of the European Bioinformatics Institute at the European Molecular Biology Laboratory used DNA to store a set of Shakespeare's sonnets, a recording of Martin Luther King's "I Have a Dream" speech, a photograph of the laboratory and an early research paper by James Watson and Francis Crick, who discovered DNA. Goldman and Birney then read back the data with 100 percent accuracy.
Bioinformatics Tools for Pairwise Sequence Alignment
Pairwise Sequence Alignment is used to identify regions of similarity that may indicate functional, structural and/or evolutionary relationships between two biological sequences (protein or nucleic acid). By contrast, Multiple Sequence Alignment (MSA) is the alignment of three or more biological sequences of similar length. From the output of MSA applications, homology can be inferred and the evolutionary relationship between the sequences studied. Global Alignment
researchers produce first complete computer model of an organism
July 19, 2012 A mammoth effort has produced a complete computational model of the bacterium Mycoplasma genitalium, opening the door for biological computer-aided design. By Max McClure
Scientific collections
The DNA Bank of Senckenberg and BiK-F Molecular data, particularly DNA sequences, are increasingly important for biosystematics, ecology and nature conservation. DNA sequences and fingerprints is routinely generated by many research groups because some of the most interesting questions about the evolution of life or the interactions between organisms in ecosystems cannot be answered without such data. The Senckenberg Research Institute and Natural History Museum (SGN) houses millions of collections that form a huge archive for basic research in this field. At room temperature, DNA slowly degrades. It is technically difficult to isolate intact DNA from old museum collections.
