Bufotenin Bufotenin (5-HO-DMT, N,N-dimethylserotonin), is a tryptamine related to the neurotransmitter serotonin. It is an alkaloid found in the skin of some species of toads; in mushrooms, higher plants, and mammals.[1] The name bufotenin originates from the Bufo genus of toads, which includes several species of psychoactive toads, most notably Incilius alvarius, that secrete bufotoxins from their parotoid glands.[2] Bufotenin is similar in chemical structure to the psychedelics psilocin (4-HO-DMT), 5-MeO-DMT, and DMT, chemicals which also occur in some of the same fungus, plant, and animal species as bufotenin. The psychoactivity of bufotenin has been disputed, though recent studies suggest it is similar in nature to 5-MeO-DMT. Nomenclature[edit] Bufotenin (bufotenine) is also known by the chemical names 5-hydroxy-N,N-dimethyltryptamine (5-HO-DMT), N,N-dimethyl-5-hydroxytryptamine, dimethyl serotonin,[3] and mappine.[3] History[edit] Sources[edit] Toads[edit] Anadenanthera seeds[edit] In 1956, Dr.
The Psychadellic Chemist By DENNIS ROMERO LAFAYETTE, Calif. -- Perhaps it was a sign of things to come when a seven-story Monterrey Pine came crashing down on the property of old Alexander T. Shulgin--Sasha, they call him--missing his musty cobweb-entangled drug lab by inches. It could have been a good sign because the cantankerous 70-year-old wasn't around the back-yard workshop conducting one of his legendary experiments, which have been known to involve him downing any number of the new psychedelic drugs he invents in the name of science. Imagine losing your mind on some unknown compound with unknown powers (some of this stuff makes LSD look like Vitamin D)--and a tree the length of three buses rocks your world to Richter proportions. Maybe, though, it was a sign of nefarious things to come. To tell the truth, Sasha Shulgin doesn't much care anymore what the government thinks. He's tippy-toed around the law and the lawmen for long enough--30 years now. Shulgin met Ann at Berkeley in 1979.
Essential First Aid Item: Activated Carbon Activated carbon, in powdered form, should be in every medicine cabinet and first aid kit. It is also known as activated charcoal. It is used around the world as a universal antidote for hundreds of poisons, including arsenic, mercury, pesticides, strychnine, warfarin, hemlock, E. Coli endotoxin, and gasoline. Over 4,000 chemicals, drugs, plant and microbial toxins, allergens, venoms, and wastes are effectively neutralized by activated charcoal, when it is given in sufficient quantities. In 1813, French chemist Michel Bertrand swallowed five grams of arsenic trioxide: 150 times the lethal dose. In 1831, in front of his distinguished colleagues at the French Academy of Medicine, Professor Touery drank a deadly cocktail of strychnine and lived to tell the tale. We witnessed the saving power of activated charcoal ourselves, when one member of our household experienced a severe allergic reaction to an unknown ingredient from a restaurant. Manufacture and Storage Other Uses Related Articles
Drug profiles Drug profiles scientifically sound descriptions of drugs in the form of ‘drug profiles’. Presented in a standardised way, each profile briefly gives the chemistry, pharmacology, synthesis and precursors of each substance, as well as analysis, physical form (e.g. powder, tablet) and mode of use (e.g. ingested, snorted, injected). Most of the substances covered are controlled internationally by United Nations conventions. Presented in a standardised way, each profile briefly gives the chemistry, pharmacology, synthesis and precursors of each substance, as well as analysis, physical form (e.g. powder, tablet) and mode of use (e.g. ingested, snorted, injected). Where appropriate, the profiles also contain sections on prevalence, street price and typical levels of purity, which will be updated annually on the basis of information provided by the Reitox network. The profiles were conceived to offer EMCDDA audiences clear and easily accessible information on individual drugs.