The driving force for molecular evolution of translation The Cronin Group Recent Publications 284. Assembly and core transformation properties of two tetrahedral clusters: [FeIII13P8W60O227(OH)15(H2O)2]30- and [FeIII13P8W60O224(OH)12(PO4)4]33-, P. I. 283. 282. 281. 280. 279. 278. 277. 276. 275. 274. 273. 272. 271. 270. 269. 267. 266. 265. 264. 263. 0D to 1D Switching of Hybrid Polyoxometalate Assemblies at the Nanoscale by Using Molecular Control, W. 262. 261. 260. 259. 258. 257. 256. 255. 254. 253. 252. 3D-printed devices for continuous-flow organic chemistry, V. 251. 250. 249. 248. 247. 246. 245. 244. 243. 242. 241. 240. 239. 238. 237. 236. 235. 234. 233.
Diseases - Manual - Activity 3, page 1 At a Glance Focus: Students investigate the growth of bacteria in the presence of antibiotics and use the results to explain a case of antibiotic-resistant tuberculosis, presented in an Internet-based interview. Major Concepts: The re-emergence of some diseases can be explained by evolution of the infectious agent (for example, mutations in bacterial genes that confer resistance to antibiotics used to treat the diseases). Objectives: After completing this activity, students will be able to explain how antibiotic treatment results in populations of bacteria that are largely resistant to the antibiotic and describe inappropriate and/or questionable uses of antibiotics. Prerequisite Knowledge: Students should be familiar with bacterial growth and with evolution by natural selection. Introduction In 1943, penicillin was introduced as the "magic bullet" for curing many infectious diseases. The primary reason for the increase in antibiotic resistance is evolution. Materials and Preparation 1.
What is life? | Science | The Observer Life looks increasingly like a chemical experiment that took over the laboratory. All living things turn to dust and ashes when they die, or, to put it another way, to constituent atoms and molecules of hydrogen, oxygen, carbon, phosphorus and so on. But, in another sense, living things do not die: they begin again, from a tiny cell, and scavenge the dust, the air and water, to find the elements necessary to fashion an aspidistra, an elephant, or an attorney-general, using only the raw materials to hand and energy from a thermonuclear reactor 93 million miles away. The freshly minted, self-replicating organism then grows up, grows old and melts away, but not before imparting a fragment of itself to generate yet another copy, but not an identical copy. The process is visible and transparent, everywhere on the planet, but it is ultimately mysterious. The mystery may endure because, once up and running, the life machine kicked up enough dust to cover its original tracks.
Life Science | Session 6 Learning Goals Which skull is a lizard and which is a snake? During this session, you will have an opportunity to build understandings to help you: Define what is meant by “species.” Describe how new species evolve as a result of variation and adaptation through natural selection. Video Overview What makes a snake a snake, and a lizard a lizard? Video Outline Deep within the basement of the Museum of Comparative Zoology at Harvard University, there is a treasure trove of life forms ready for study. Dr. Dr. A tree of life is introduced as a model that portrays how scientists think life on Earth evolved, and a scenario for vertebrate evolution is described.
Inorganic Biology | Operation Reality ™ Image credit: colourdance.deviantart.com One of the most burning and perplexing questions in biology today is: just what is life? While on the surface it seems obvious, the line between life and non-life is much blurrier than it seems. At the microscopic level, it becomes nearly impossible to distinguish the processes of life from other chemical reactions that are going on around us all the time. The mascot for this debate is the humble virus. There is a large degree of disagreement about what exactly viruses are. Now, the debate is about to get even more complicated. The applications of these iCHELLS are wide-ranged. Many people are familiar with the concept of nanobots, tiny molecular machines that can perform tasks on tiny scales. Below is a link to a TED talk by Professor Cronin regarding iCHELLS and his ideas: Professor Cronin’s Ted Talk on inorganic life
Transitional forms Transitional forms Fossils or organisms that show the intermediate states between an ancestral form and that of its descendants are referred to as transitional forms. There are numerous examples of transitional forms in the fossil record, providing an abundance of evidence for change over time. Pakicetus (below left), is described as an early ancestor to modern whales. A skull of the gray whale that roams the seas today (below right) has its nostrils placed at the top of its skull. Note that the nostril placement in Aetiocetus is intermediate between the ancestral form Pakicetus and the modern gray whale — an excellent example of a transitional form in the fossil record!
Scientists take first step towards creating 'inorganic life' Scientists at the University of Glasgow say they have taken their first tentative steps towards creating 'life' from inorganic chemicals potentially defining the new area of 'inorganic biology'. Professor Lee Cronin, Gardiner Chair of Chemistry in the College of Science and Engineering, and his team have demonstrated a new way of making inorganic-chemical-cells or iCHELLs. Prof Cronin said: "All life on earth is based on organic biology (i.e. carbon in the form of amino acids, nucleotides, and sugars, etc.) but the inorganic world is considered to be inanimate. "What we are trying do is create self-replicating, evolving inorganic cells that would essentially be alive. You could call it inorganic biology." The cells can be compartmentalised by creating internal membranes that control the passage of materials and energy through them, meaning several chemical processes can be isolated within the same cell -- just like biological cells.