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Methamphetamine

Methamphetamine[note 1] (pronunciation: /ˌmɛθæmˈfɛtəmiːn/; contracted from N-methyl-alpha-methylphenethylamine) is a neurotoxin and potent psychostimulant of the phenethylamine and amphetamine classes that is used to treat attention deficit hyperactivity disorder (ADHD) and obesity. Methamphetamine exists as two enantiomers, dextrorotary and levorotary.[note 2] Dextromethamphetamine is a stronger central nervous system (CNS) stimulant than levomethamphetamine; however, both are addictive and produce the same toxicity symptoms at high doses. Although rarely prescribed due to the potential risks, methamphetamine hydrochloride is approved by the United States Food and Drug Administration (USFDA) under the trade name Desoxyn. Recreationally, methamphetamine is used to increase sexual desire, lift the mood, and increase energy, allowing some users to engage in sexual activity continuously for several days straight. Uses Medical Recreational Crystal meth – illicit methamphetamine hydrochloride

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Substituted amphetamine Substituted amphetamines are a chemical class of stimulants, entactogens, hallucinogens, and other drugs. They feature a phenethylamine core with a methyl group attached to the alpha carbon resulting in amphetamine, along with additional substitutions. Examples of amphetamines are amphetamine (itself), methamphetamine, ephedrine, cathinone, MDMA ("Ecstasy"), and DOM ("STP"). List of substituted amphetamines[edit] Structural formula of amphetamine History[edit]

Chemotherapy Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is the treatment of cancer with one or more cytotoxic anti-neoplastic drugs (chemotherapeutic agents) as part of a standardized regimen. Chemotherapy may be given with a curative intent or it may aim to prolong life or to palliate symptoms. It is often used in conjunction with other cancer treatments, such as radiation therapy, surgery, and/or hyperthermia therapy. Certain chemotherapeutic agents also have a role in the treatment of other conditions, including ankylosing spondylitis, multiple sclerosis, Crohn's disease, psoriasis, psoriatic arthritis, systemic lupus erythematosus, rheumatoid arthritis, and scleroderma. Traditional chemotherapeutic agents act by killing cells that divide rapidly, one of the main properties of most cancer cells. This means that chemotherapy also harms cells that divide rapidly under normal circumstances: cells in the bone marrow, digestive tract, and hair follicles.

Mescaline Mescaline or 3,4,5-trimethoxyphenethylamine is a naturally occurring psychedelic alkaloid of the phenethylamine class, known for its hallucinogenic effects similar to those of LSD and psilocybin. It shares strong structural similarities with the catecholamine dopamine. It occurs naturally in the peyote cactus (Lophophora williamsii),[1] the San Pedro cactus[2] (Echinopsis pachanoi) and in the Peruvian torch (Echinopsis peruviana), and as well in a number of other members of the Cactaceae plant family. Pseudoephedrine Pseudoephedrine (/ˌsjuːdoʊ.ɨˈfɛdrɪn/ or /ˌsjuːdoʊˈɛfɨdriːn/; PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. It may be used as a nasal/sinus decongestant, as a stimulant,[2] or as a wakefulness-promoting agent.[3] Chemistry[edit] Pseudoephedrine is a diastereomer of ephedrine and is readily reduced into methamphetamine or oxidized into methcathinone.

Methamphetamine - I Wish Things Could Be as Simple as they Were on Meth - 20413 Citation: abnormallydizzy. "I Wish Things Could Be as Simple as they Were on Meth: An Experience with Methamphetamine (ID 20413)". Erowid.org. Nov 13, 2005. erowid.org/exp/20413 I was in the middle of my drug experimentation phase, in which I was trying every drug I could lay my hands on, save heroin or coke (Because of personal fears of danger and addiction. Interestingly enough, my mind didn't place this fear on meth).

Ephedrine Ephedrine (/ɨˈfɛdrɪn/ or /ˈɛfɨdriːn/; not to be confused with ephedrone) is a sympathomimetic amine commonly used as a stimulant, appetite suppressant, concentration aid, decongestant, and to treat hypotension associated with anaesthesia. The herb má huáng (麻黄, Ephedra sinica), used in traditional Chinese medicine, contains ephedrine and pseudoephedrine as its principal active constituents. The same may be true of other herbal products containing extracts from other Ephedra species. Ricin Toxicity[edit] Castor beans The seeds can be crushed in an oil press to extract castor oil. This leaves behind the spent crushed seeds, called variously the 'cake', 'oil cake', and 'press cake'. While the oil cake from coconut, peanuts, and sometimes cotton seeds can be used as either cattle feed and/or fertilizer, the toxic nature of castor precludes them from being used as feed.[11] Accidental ingestion of Ricinus communis cake to be used as fertilizer has been reported to be responsible for fatal ricin poisoning in animals.[4][12]

Methadone Methadone (also known as Symoron, Dolophine, Amidone, Methadose, Physeptone, Heptadon and many other names) is a synthetic opioid. It is used medically as an analgesic and a maintenance anti-addictive and reductive preparation for use by patients with opioid dependency. It was developed in Germany in 1937, mainly because Germany required a reliable internal source of opiates. Because it is an acyclic analog of morphine or heroin, methadone acts on the same opioid receptors as these drugs, and thus has many of the same effects. Methadone is also used in managing severe chronic pain, owing to its long duration of action, extremely powerful effects, and very low cost. Methadone was introduced into the United States in 1947 by Eli Lilly and Company.

Phenethylamine Occurrence[edit] Phenethylamine is widely distributed throughout the plant kingdom.[5] Chemistry[edit] Synthesis[edit] One method for preparing β-phenethylamine, set forth in J. Methamphetamine - Shooting It Is the Devil - 63759 Citation: LLamarama. "Shooting It Is the Devil: An Experience with Methamphetamine (ID 63759)". Erowid.org.

Cathinone Cathinone /ˈkæθɨnoʊn/, benzoylethanamine, or β-ketone-amphetamine also known as hagigat (Hebrew: חגיגת‎) in Israel,[2] is a monoamine alkaloid found in the shrub Catha edulis (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines. Cathinone induces the release of dopamine from striatal preparations that are prelabelled either with dopamine or its precursors.[3] It is probably the main contributor to the stimulant effect of Catha edulis. Cathinone differs from many other amphetamines in that it has a ketone functional group. Other amphetamines that share this structure include the antidepressant bupropion and the stimulant methcathinone, among others. Internationally, cathinone is a Schedule I drug under the Convention on Psychotropic Substances.[4] Circa 1993, the DEA added cathinone to the Controlled Substances Act's Schedule I. Chemistry[edit]

Cerebral palsy Cerebral palsy (CP) is a general term for a group of permanent, non-progressive movement disorders that cause physical disability,[1] mainly in the areas of body movement.[2] There may also be problems with sensation, depth perception, and communication ability. Difficulty with cognition and epilepsy is found in about one-third of cases. There are a number of subtypes including a type characterized by spasticity, a type characterized by poor co-ordination, and types which feature both symptoms or neither. Cerebral palsy is caused by damage to the motor control centers of the developing brain and can occur during pregnancy, during childbirth, or after birth up to about age three.[3][4] About 2% of all cerebral palsy cases are believed to be due to a genetic cause.[5] Cerebral palsy is not an infectious disease and is not contagious. Most cases are diagnosed at a young age rather than during adolescence or adulthood.

Crack - Crack cocaine Crack cocaine ‘rocks’. Appearance and characteristics In purer forms, crack rocks appear as off-white nuggets with jagged edges,[3] with a slightly higher density than candle wax. Purer forms of crack resemble a hard brittle plastic, in crystalline form[3] (snaps when broken). A crack rock acts as a local anesthetic (see: cocaine), numbing the tongue or mouth only where directly placed. Purer forms of crack will sink in water or melt at the edges when near a flame (crack vaporizes at 90 °C, 194 °F).[2]

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