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Genetic Engineering & Biotechnology News Birth and expression evolution of mammalian microRNA genes + Author Affiliations + Author Notes ↵Present addresses: 4GenoSplice technology, 75010 Paris, France; ↵5 Harvard Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts 02138, USA; ↵6 Broad Institute, Cambridge, Massachusetts 02142, USA. Abstract MicroRNAs (miRNAs) are major post-transcriptional regulators of gene expression, yet their origins and functional evolution in mammals remain little understood due to the lack of appropriate comparative data.
Systems Biology Markup Language Nature A personal subscription will give you access to the archive dating back to January 1997. Access via a site license includes a minimum of four years; institutions can add additional archived content to their license at any time. Recommend site license access to your institution. Alternatively, any of the above articles can be purchased individually via our document delivery service. For a taste of the Nature archive visit The History of the Journal Nature, with free highlights of the breakthrough research published in Nature in the form of timelines, videos, essays and a journal club. Nature New Biology and Nature Physical Sciences are currently being digitized and will be added in 2010.
Human Givens Institute: Holistic & Scientific Approach To Your Needs Nucleic Acids Research Popular press wildly overblows “gene for humanity” I’m about to describe one of the worst examples of science journalism I’ve seen in ages. It is a lesson on how the popular press overblows interesting scientific findings into world-shaking discoveries. miRNAs, or “microRNAs”, are small molecules of RNA, produced by the DNA, that have recently been discovered to play an important role in gene regulation, usually by binding to a “regulatory portion” of a gene and silencing that gene (i.e., preventing its expression). A new paper in Nature Communications by Hai Yang Hu and others (some of them from the University of Edinburgh) report a new miRNA that is specific to the human lineage: it’s not present in our closest relative, chimpanzees, or in 10 other species. And indeed they did find one, which is what their report is about. First, what did Hu et al. find? MicroRNA-mediated gene regulation is important in many physiological processes. True, but as the authors note, that “microdeleted region” contains a lot more genes than just miR-941:
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