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Athérosclérose sur Wikipedia.

Athérosclérose sur Wikipedia.
Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a specific form of arteriosclerosis in which an artery wall thickens as a result of the accumulation of calcium and fatty materials such as cholesterol and triglyceride. It reduces the elasticity of the artery walls and therefore allows less blood to travel through. This also increases blood pressure. It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, caused largely by the accumulation of macrophages and white blood cells and promoted by low-density lipoproteins (LDL, plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high-density lipoproteins (HDL) (see apoA-1 Milano). It is commonly referred to as a hardening or furring of the arteries. These complications of advanced atherosclerosis are chronic, slowly progressive and cumulative. Signs and symptoms[edit]

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C a r d i o V a x The Medical Need The death rate from cardiovascular disease has declined by one third in the period of 1994–2004. This decline is the result of new pharmaceuticals, surgical practices, and medical devices being introduced. In spite of these medical advances, cardiovascular disease still remains the number 1 killer, not only of Americans, but of people worldwide.

Balloon angioplasty - short segment ©Copyright 2014 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Key to heart failure, new therapies on horizon Public release date: 5-Mar-2013 [ Print | E-mail Share ] [ Close Window ] Contact: Jeremy 215-707-7882Temple University Health System (Philadelphia, PA) – Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step underlying the condition that could aid the development of new drugs to treat and possibly prevent it.

Stressed VWF Proteins Can Cause Blood Clots Rice University researchers in the lab of Ching-Hwa Kiang use the bobbing needle from an atomic force microscope to grab and pull individual protein molecules. By stretching the proteins, Kiang’s team can measure the precise physical forces that shape them. Credit: C. New Injectable Gel Repairs Muscle Damage After a Heart Attack A new injectable hydrogel capable of repairing heart tissue after a heart attack has been deemed safe by bioengineers at the University of California, San Diego (UCSD) and is ready for clinical testing in humans this year, according to a recent study published in Science Translational Medicine. In the United States, an estimated 785,000 heart attacks occur each year, according to a UCSD press release. While a growing number of people survive heart attacks, many patients later develop heart failure due to cardiac tissue damage, “for which the five-year survival rate is only 50 percent,” researchers wrote. "Our data show that this hydrogel can increase cardiac muscle and reduce scar tissue in the region damaged by the heart attack, which prevents heart failure,” said lead researcher Karen Christman, a UCSD professor in the Department of Bioengineering.

Mummies reveal that clogged arteries plagued the ancient world Clogged arteries are seen as the quintessential symptom of an unhealthy modern lifestyle. But the condition was common across the ancient world, even among active hunter–gatherers with no access to junk food, a study of mummies has found. “There’s a belief that if we go back in time, everything’s going to be OK,” says cardiologist Greg Thomas of the University of California, Irvine, a senior member of the study team. “But these mummies still have coronary artery disease.” The paper is published in the current issue of The Lancet1. A modified virus as a pacemaker That's why it's really important to pick your viral vectors carefully. Some vectors are prone to inserting into areas of active chromatin, which is where they can integrate in a way to turn off tumor suppressors or activate oncogenes. But there are viral vectors out there that are more prone to integration into non-active chromatin. And different vectors infect different cell types, so restricting the cell type is often just as important. Lentiviruses are an option.

Flu Shot Prevents Heart Attacks If you’re tempted to skip your flu shot, consider this: Getting vaccinated cuts risk for a heart attack or stroke by up to 50 percent, according to two studies presented at the Canadian Cardiovascular Congress. Scientists from TIMU Study Group and Network for Innovation in Clinical Research analyzed published clinical trials involving a total of 3,227 patients, half of whom had been diagnosed with heart disease. Participants, whose average age was 60, were randomly assigned to either receive flu vaccine or a placebo shot, then their health was tracked for 12 months. Those who got the flu shot were 50 percent less likely to suffer major cardiac events (such as heart attacks or strokes) and 40 percent less likely to die of cardiac causes. Similar trends were found in patients with and without previous heart disease. The findings suggest “that flu vaccine is a heart vaccine,” lead study author Jacob Udell told Fox News.

First drug to improve heart failure mortality in over a decade Lisbon, 25 May 2013: Coenzyme Q10 decreases all cause mortality by half, according to the results of a multicentre randomised double blind trial presented today at Heart Failure 2013 congress. It is the first drug to improve heart failure mortality in over a decade and should be added to standard treatment, according to lead author Professor Svend Aage Mortensen (Copenhagen, Denmark). Heart Failure 2013 is being held from 25-28 May in Lisbon, Portugal. It is the main annual meeting of the Heart Failure Association of the European Society of Cardiology (1). Coenzyme Q10 (CoQ10) occurs naturally in the body and is essential to survival.