EUROPE 10/02/99 Opinion on the safety of boric acid in medicinal products adopted on 10 February 1999 Question The Committee is asked the following three questions: Does the safety profile of boric acid support its use in parenteral medications intended for neonates ? Should the current contraindication for boric acid in the guideline on the excipients in the label and package leaflet of medicinal products for human use remain in its current form ? Does the safety profile and clinical experience of boric acid support the establishment of threshold dose levels below which the contraindication should not be labelled ? Context of the question The question is asked in the frame of a "Guideline on the excipients in the label and package leaflet of medicinal products for human use" approved by the Pharmaceutical Committee which became applicable from 1st September 1997.
Cyclospora cayetanensis Cyclospora cayetanensis is a protozoan that causes disease in humans, and perhaps primates. It has been linked in the United States to fecally contaminated imported raspberries and was virtually unknown before about 1990, but has been on the rise since. The health risk associated with the disease is usually confined to adult foreigners visiting regions where the species is endemic and acquiring the infection, which is why C. cayetanensis has been labeled as causing "traveler's diarrhea."
Stowage of Fish in Chilled Sea Water Contents Index Accompanying NotesTable of Contents TORRY ADVISORY NOTE No. 73 PRO LIGNO - DEC 2007 - EVALUATION OF BORIC ACID/VEGETABLE OIL COMBINATIONS FOR WOOD BIOLOGICAL RESISTANCE AND REDUCTION OF BORON Florent LYON PhD student-Laboratory of mechanics and civil engineering-University of Montpellier II Adress: CC 048 Place Eugene Bataillon, 34095 Montpellier Cedex 5, France. Tel : 0033 (0) 467149344. Fax : 0033 (0) 467144792. OMS - Boron in drinking-water Effects on experimental animals and in vitro test systems Acute exposure The oral LD50 values for boric acid or borax in mice and rats are in the range of about 400–700 mg of boron per kg of body weight (Pfeiffer et al., 1945; Weir & Fisher, 1972). Oral LD50 values in the range of 250–350 mg of boron per kg of body weight for boric acid or borax exposure have been reported for guinea-pigs, dogs, rabbits, and cats (Pfeiffer et al., 1945; Verbitskaya, 1975). Signs of acute toxicity for both borax and boric acid in animals given single large doses orally include depression, ataxia, convulsions, and death; kidney degeneration and testicular atrophy are also observed (Larsen, 1988). Short-term exposure
CDC EID – OCT 2011 - Prevalence and Molecular Characterization of Cyclospora cayetanensis, Henan, China. Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options CDC Home CDC 24/7: Saving Lives. Protecting People PARLEMENT EUROPEEN 01/10/10 Question en attente de réponse : E-6945/2010 The issue of the use of sea water for human consumption The issue of the use of sea water for human consumption was discussed during the Standing Committee of Food Chain and Animal health on 16 February 2010 at the request of a Member State. It emerged that sea water for human consumption was only authorised in the Netherlands, but the authorisation had been withdrawn. In that Committee it was agreed that:
J. Antimicrob. Chemother. (2009) Antifungal mechanisms supporting boric acid therapy of Candida vaginitis + Author Affiliations *Corresponding author. Tel: +1-515-271-1559; Fax: +1-515-271-1644; E-mail: firstname.lastname@example.org Received June 13, 2008. Revision requested August 4, 2008. Revision received September 24, 2008.