Scientists unveil tools for rewriting the code of life MIT and Harvard researchers have developed technologies that could be used to rewrite the genetic code of a living cell, allowing them to make large-scale edits to the cell’s genome. Such technology could enable scientists to design cells that build proteins not found in nature, or engineer bacteria that are resistant to any type of viral infection. The technology, described in the July 15 issue of Science, can overwrite specific DNA sequences throughout the genome, similar to the find-and-replace function in word-processing programs. Using this approach, the researchers can make hundreds of targeted edits to the genome of E. coli, apparently without disrupting the cells’ function. “We did get some skepticism from biologists early on,” says Peter Carr, senior research staff at MIT’s Lincoln Laboratory (and formerly of the MIT Media Lab), who is one of the paper’s lead authors. DNA consists of long strings of “letters” that code for specific amino acids. ‘Plug and play’
276 QUESTIONS TO ASK BEFORE YOU MARRY 1. Are you working on your chosen field? 2. How many hours a week do you work? 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22 Do you believe in prenuptial agreements? 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 36. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 48. 50. 51. 52. 53. 54. 55. 56. 57. 58. 58. 60. 61. 62. 63. 64. 65. 66. 67. 68. P.. 70. 71. 72. 73. 74. 75. 76. 77. 78. 70. 80. 81. 82. 83. 84. 85. 86. 87. 88. 88. 90. 91. 92. 93. 94. 95. 96. 97. 96. 97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 106. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 122. 123. 124. 125. 126. 127. 128. 128. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. 140. 141. 142. 143. 144. 145. 146. 147. 148. 149. 150. 151. 152. 153. 154. 156. 156. 157. 158. 159. 100. 161. 162. 163. 164. 185. 166. 167. 168. 169. 170. 171. 172. 173. 174. 175. 176. 177. 178. 179. 180. 181. 182. 183. 184. 185. 186. 187. 168. 189. 190. 191. 192. 193. 194. 195. 196. 197.
Everyday Objects Under Electron Microscope <div style="display:none"><img src=" ID>&oid=<Offer ID>" /></div> EgoTV 25 Everyday Objects Under an Electron Microscope digg March 13, 2012 at 5:24 am You come into contact with millions of different objects every day. Most Popular Today WTF Photo of the Day More Photos What’s Trending Now! Friends TruTV Maxim Magazine Uproxx © Hutch Media.
Male Chromosomes Are Not Dying Soon, Study Finds : News Update Date: Jan 11, 2014 05:31 PM EST A new study has challenged the notion that Y chromosomes are largely unimportant and will no longer exist in the next 5 million years. (Photo : Image Editor/Flickr) A new study has challenged the notion that Y chromosomes are largely unimportant and will no longer exist in the next 5 million years. The study has based its findings on a comparison of Y chromosomes in eight African and eight European men. “The Y chromosome has lost 90 percent of the genes it once shared with the X chromosome, and some scientists have speculated that the Y chromosome will disappear in less than 5 million years,” said evolutionary biologist Melissa A. The study also acknowledged that few mammals have completely lost their Y chromosome. “Our study demonstrates that the genes that have been maintained, and those that migrated from the X to the Y, are important, and the human Y is going to stick around for a long while,” Sayres added. “Melissa’s results are quite stunning.
Nucleus Medical Media: Medical Video, Animation & Illustration Share Book Recommendations With Your Friends, Join Book Clubs, Answer Trivia 50 Things to Grill in Foil : Recipes and Cooking How to make a foil packet: 1. Lay a large sheet of heavy-duty foil or a double layer of regular foil on a flat surface. (Use nonstick foil where noted.) 2. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Rediscovering Biology - Case Studies: The Genetics of Resistance to HIV Infection This case uses the example of HIV, to explore the relationships between viruses, cells and the immune system, and the role of genes in disease resistance. An animation explains PCR (polymerase chain reaction) and electrophoresis and their practical use as a genetic test. We will see how mutations in an HIV receptor confer relative reslstance to infection. We will find out how often this mutation occurs in the general population, and see data about additional mechanisms of HIV resistance. Before beginning this case study, you may want to review these related materials: • HIV and AIDS Video • HIV and AIDS Online Text • Human Evolution Online Text • Genomics Video • Genomics Online Text
Mutated DNA Causes No-Fingerprint Disease Almost every person is born with fingerprints, and everyone's are unique. But people with a rare disease known as adermatoglyphia do not have fingerprints from birth. Affecting only four known extended families worldwide, the condition is also called immigration-delay disease, since a lack of fingerprints makes it difficult for people to cross international borders. In an effort to find the cause of the disease, dermatologist Eli Sprecher sequenced the DNA of 16 members of one family with adermatoglyphia in Switzerland . Seven had normal fingerprints, and the other nine did not. After investigating a number of genes to find evidence of mutation, the researchers came up empty-handed—until a grad student finally found the culprit, a smaller version of a gene called SMARCAD1. ( Get a genetics overview. ) The larger SMARCAD1 is expressed throughout the body, but the smaller form acts only on the skin . (See skin pictures .) American Journal of Human Genetics.
CheapCooking.com: Cheap Quick Easy Recipes for your Family, Cheap Healthy Recipes, Grocery List on a Budget Evolution in an RNA world. [Cold Spring Harb Symp Quant Biol. 2009] - PubMed result