Hypertension overview - NICE Pathways. Short Text Clinical management of primary hypertension in adults Introduction This pathway covers the clinical management of primary hypertension in adults.
Hypertension is one of the most important preventable causes of premature morbidity and mortality in the UK, and its management is one of the most common interventions in primary care. The MDU - the UK's leading Medical Defence Organisation. Pathophysiology of dyslipidaemia in the metabolic syndrome. + Author Affiliations Correspondence to: Dr G D Kolovou Onassis Cardiac Surgery Centre, 356 Sygrou Avenue 176 74 Athens, Greece; genkolovou@mail.gr Received 15 June 2004 Accepted 1 November 2004 Abstract The insulin resistance/metabolic syndrome is characterised by the variable coexistence of hyperinsulinaemia, obesity, dyslipidaemia, and hypertension.
The pathogenesis of the syndrome has multiple origins, but obesity and sedentary lifestyle coupled with diet and still largely unknown genetic factors clearly interact to produce the syndrome. Dyslipidaemia, the hallmark of the metabolic syndrome, includes increased flux of free fatty acids, raised triglycerides, apolipoprotein B, and small dense low density lipoprotein, and decreased high density lipoprotein cholesterol. BCSH - The British Committee for Standards in Haematology. National Institute for Health and Clinical Excellence.
Donadio JV, Grande JP articles: NEJM.org.
E&pH Balance. Insulin and Cardiovascular Disease: Paris Prospective Study.