Bioinformatics Software for Sequence alignment, sequence analysis, BLAST, Mr Bayes, ClustalW
DNAWorks (v3.2.2) The availability of sequences of entire genomes has dramatically increased the number of protein targets, many of which will need to be overexpressed in cells other than the original source of DNA. Gene synthesis often provides a fast and economically efficient approach. The synthetic gene can be optimized for expression and constructed for easy mutational manipulation without regard to the parent genome. Yet design and construction of synthetic genes, especially those coding for large proteins, can be a slow, difficult and confusing process. DNAWorks automates the design of oligonucleotides for gene synthesis by PCR-based methods. DNAWorks at Helix Systems DNAWorks at Helix Systems
Tools
Sci-Ed Software - Products Sci-Ed Software - Products Clone Manager Basic acts as an expert system to help with cloning simulation, enzyme operations and graphic map drawing. You can also use Clone Manager as a quick and easy way to view or edit sequence files, find open reading frames, translate genes, or find genes or text in files. Use Enzymes, Simulate Cloning Find enzyme sites, view enzyme info Do restriction enzyme analysis Updated enzyme list display Cut, ligate DNA, modify molecule ends Plan Cloning, Gateway, Topo Cloning Wizards Draw Graphic Maps Prepare high-resolution graphic maps Print, copy to clipboard, export to file Enhanced Views of graphic map
The DNA design tool for today’s molecular biologists Capture your entire gene design process in one efficient application, using a range of design tools purposely built for the task: Intelligent, fast, and easy-to-use algorithms for in silico cloning, codon optimization, back translation and primer design. Gene Designer Software and Demos - DNA2.0 Gene Designer Software and Demos - DNA2.0