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May Affymetrix CEO, Kevin King, remarked about the role microarrays continue to play despite the advancement of new sequencing technologies, such as RNA-Seq, during their recent Q1 2011 earnings call. …a team led by Ron Davis at the Stanford Genome Technology Center, compared a custom Affy exon array to next-generation sequencing for understanding gene expression and Genome 1 identification of alternative splicing as well as infecting coding snips and non-coding transcripts.
Jun Recently, ultra high-throughput sequencing of RNA (RNA-Seq) has been developed as an approach for analysis of gene expression.
Jun Chickpea is an important food legume crop but lags in the availability of genomic resources. In this study, we have generated about two million high-quality sequences of average length of 372 bp using pyrosequencing technology.
Aug Researchers at UC Berkeley have shown that priming using random hexamers biases the nucleotide content of RNA-Seq reads and that this bias also affects the uniformity of the locations of the reads along expressed transcripts.
Sep Morphological characters are the result of developmental gene expression. The identity of a character is ultimately grounded in the gene regulatory network directing development and thus whole-genome gene expression data can provide evidence about character identity.
Sep RNA-Seq reveals plant microRNAs regulating expression in mammals
Sep Mosquito-borne infectious diseases pose a severe threat to public health in many areas of the world. Efficient approaches are required for screening wild mosquito populations to detect known and unknown pathogens.
Jun SeqGene is an open-source software for mining next-gen sequencing datasets, focusing on post-alignment quality control, SNP and indel identification and annotation, RNA expression quantification, allele specific expression, and expression-genotying association analysis.