background preloader

Pharmaceutical Lab

Facebook Twitter

Sterilizer. Mass Spectrometry. Mass Spectrometry 1.

Mass Spectrometry

The Mass Spectrometer In order to measure the characteristics of individual molecules, a mass spectrometer converts them to ions so that they can be moved about and manipulated by external electric and magnetic fields. The three essential functions of a mass spectrometer, and the associated components, are: Because ions are very reactive and short-lived, their formation and manipulation must be conducted in a vacuum. Atmospheric pressure is around 760 torr (mm of mercury). When a high energy electron collides with a molecule it often ionizes it by knocking away one of the molecular electrons (either bonding or non-bonding). 2. Since a molecule of carbon dioxide is composed of only three atoms, its mass spectrum is very simple.

Most stable organic compounds have an even number of total electrons, reflecting the fact that electrons occupy atomic and molecular orbitals in pairs. This distinction is illustrated nicely by the following two examples. 3. 4. 5. Pharmaceutical Lab Equipment Key Terms: Guide: Business.com. There are many different types of pharmaceutical lab equipment.

Pharmaceutical Lab Equipment Key Terms: Guide: Business.com

After all, laboratories develop and manufacture the medications on the market today. In order to comply with regulations, they must use items such as sterilization equipment and in order to handle the chemistry behind developing and mixing today’s drugs, scientists must have access to tools such as microscopes and centrifuges. Understanding some of the key terms related to pharmaceutical lab equipment will give people a better understanding of what types of things used to develop and manufacture today’s medications.

Capsule sealing Filling and sealing equipment fills those medications that come in capsule form. Sterilizer Sterilizers clean and decontaminate laboratory equipment and utensils. Microscopes Microscopes are pieces of pharmaceutical lab equipment used to magnify objects you can't see with the naked eye. Capsule Band Sealing Equipment. The benefits of capsule band-sealing A dosage delivery system is only as strong as its seal.

Capsule Band Sealing Equipment

In addition to isolating contents inside the capsule, capsule banding has several end benefits: Assures the user that their dosage has been free of tamperingHelps reduce the likelihood of the product being counterfeitedEasy to visually inspectAdds mechanical strength to the capsuleColored seals create brand differentiationMeets the requirements for tamper evidence for OTC productsEffectively prevents leakage in liquid-filled capsulesImproves stabilityA significant reduction in oxygen diffusion S-15/40/100: HICAPSEAL Capsule Sealing Machine The HICAPSEAL Machines are fully automated and effectively seal capsules filled with liquids of varying viscosities.

S-1: Bench-Top Capsule Band-Sealer. CFS 1200 Brochure 1. CFS Liquid filling & Sealing Machines. The Capsugel CFS capsule liquid filling and sealing system is specifically designed to allow formulation scientists to better exploit the potential of lipid-based formulations for poorly soluble compounds, helping accelerate the development timeline and achieve ‘faster time to first in human’.

CFS Liquid filling & Sealing Machines

Options to Meet Your Needs The Capsugel CFS 1200™ system is a bench-top cGMP-compliant machine that fills up to 1,200 capsules per hour with liquid or semi-solid formulations using Capsugel’s proprietary Liquid Encapsulation Microspray Sealing (LEMS®) technology and eliminating the need for banding. “It (Capsugel CFS 1200) has more than paid for itself in terms of saving the cost of contract development work and clinical manufacturing”.- Pharmaceutical Company To read more customer testimonials, click here.

Capsugel CFS 1200 Liquid Filling and Sealing Machine The Capsugel CFS 1200 automated filler and sealer comes with a complete installation package, including a comprehensive validation package. The mass spectrometer - how it works. Assuming 1+ ions, stream A has the lightest ions, stream B the next lightest and stream C the heaviest.

the mass spectrometer - how it works

Lighter ions are going to be more deflected than heavy ones. Detection Only ion stream B makes it right through the machine to the ion detector. The other ions collide with the walls where they will pick up electrons and be neutralised. Eventually, they get removed from the mass spectrometer by the vacuum pump. When an ion hits the metal box, its charge is neutralised by an electron jumping from the metal on to the ion (right hand diagram).

A flow of electrons in the wire is detected as an electric current which can be amplified and recorded. Detecting the other ions How might the other ions be detected - those in streams A and C which have been lost in the machine? Mass spectrometer.