FAS Center: The Scriptome - Protocols for Manipulating Biological Data. Broad Institute Cancer Program Publications. Providing insights into NCBI resources and the science behind them. ExpEdit. Welcome to ExpEdit RNA editing is a widespread post-transcriptional molecular phenomenon that can increase proteomic diversity, by modifying the sequence of completely or partially non-functional primary transcripts, through a variety of mechanistically and evolutionarily unrelated pathways [1] . Editing by base substitution has been investigated in animals, plants and viruses [2] .
In human, the A-to-I substitution is the most frequent editing event, carried out by members of ADAR (adenosine deaminases acting on RNA) family [3] . Such alterations can be predicted by computational analyses based on the alignment of mRNA/EST sequences onto the genome of origin [4] . Recent high-throughput sequence technologies offer the unique opportunity to study entire transcriptomes in a variety of experimental conditions.
Services - Browse All Services. Ondex - data integration and visualisation. Bioinformatics, Databases and Software for Medicine. STAR - About STAR. Reactome. Home. GenePattern: Home. Science Olympiad Protein Modeling Event - The Molecular Story of XIAP. BioModels Database. MicroArray Quality Control (MAQC) MAQC-IMAQC-IIMAQC-III (also known as SEQC)Contact Information Microarrays and next-generation sequencing represent core technologies in pharmacogenomics and toxicogenomics; however, before these technologies can successfully and reliably be used in clinical practice and regulatory decision-making, standards and quality measures need to be developed.
The MAQC project is helping improve the microarray and next-generation sequencing technologies and foster their proper applications in discovery, development and review of FDA regulated products. Everyone is invited to participate in the MAQC project. Nature Biotechnology: September 2006 Issue. MyGrid » Home. Omics - Omics.org.