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http://news.bbc.co.uk/2/hi/technology/6600965.stm Brain tissue presents a huge problem for simulation because of its complexity and the sheer number of potential interactions between the elements involved. The three researchers, James Frye, Rajagopal Ananthanarayanan, and Dharmendra S Modha, laid out how they went about it in a very short research note entitled "Towards Real-Time, Mouse-Scale Cortical Simulations". Half a real mouse brain is thought to have about eight million neurons each one of which can have up to 8,000 synapses, or connections, with other nerve fibres. Modelling such a system, the trio wrote, puts "tremendous constraints on computation, communication and memory capacity of any computing platform". The team, from the IBM Almaden Research Lab and the University of Nevada, ran the simulation on a BlueGene L supercomputer that had 4,096 processors, each one of which used 256MB of memory.

BBC NEWS | Technology | Mouse brain simulated on computer

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The breve Simulation Environment | breve

What is breve? breve is a free, open-source software package which makes it easy to build 3D simulations of multi-agent systems and artificial life. Using Python , or using a simple scripting language called steve , you can define the behaviors of agents in a 3D world and observe how they interact. breve includes physical simulation and collision detection so you can simulate realistic creatures, and an OpenGL display engine so you can visualize your simulated worlds .
Thinking Machine 4 explores the invisible, elusive nature of thought. Play chess against a transparent intelligence, its evolving thought process visible on the board before you. The artwork is an artificial intelligence program, ready to play chess with the viewer. If the viewer confronts the program, the computer's thought process is sketched on screen as it plays. A map is created from the traces of literally thousands of possible futures as the program tries to decide its best move. http://turbulence.org/spotlight/thinking/index.html

Thinking Machine 4