Epidemiologic Evidence of a Relationship between Tea, Coffee, or Caffeine Consumption and Cognitive Decline. Abstract A systematic literature review of human studies relating caffeine or caffeine-rich beverages to cognitive decline reveals only 6 studies that have collected and analyzed cognition data in a prospective fashion that enables study of decline across the spectrum of cognition. These 6 studies, in general, evaluate cognitive function using the Mini Mental State Exam and base their beverage data on FFQs. Studies included in our review differed in their source populations, duration of study, and most dramatically in how their analyses were done, disallowing direct quantitative comparisons of their effect estimates.
Only one of the studies reported on all 3 exposures, coffee, tea, and caffeine, making comparisons of findings across studies more difficult. However, in general, it can be stated that for all studies of tea and most studies of coffee and caffeine, the estimates of cognitive decline were lower among consumers, although there is a lack of a distinct dose response. Footnotes. Caffeine as a Protective Factor in Dementia and Alzheimer's Disease - Journal of Alzheimer's Disease - Volume 20, Supplement 1/ 2010. Authors Marjo H. Eskelinen1, Miia Kivipelto2 1University of Eastern Finland, School of Medicine, Institute of Clinical Medicine – Neurology, Kuopio, Finland2Aging Research Center (ARC), Karolinska Institutet, Stockholm, Sweden Caffeine has well-known short-term stimulating effects on central nervous system, but the long-term impacts on cognition have been less clear.
Dementia and Alzheimer's disease (AD) are rapidly increasing public health problems in ageing populations and at the moment curative treatment is lacking. Thus, the putative protective effects of caffeine against dementia/AD are of great interest. Keywords Alzheimer's disease, caffeine, coffee, dementia, epidemiology Fulltext Preview (Small, Large) Caffeine Intake and Dementia: Systematic Review and Meta-Analysis - Journal of Alzheimer's Disease - Volume 20, Supplement 1/ 2010. Progression of brain atrophy and cognitive decline... [Neurology. 2010. JAD111781.pdf. Caffeine as a protective factor in dementia... [J Alzheimers Dis. 2010. Midlife coffee and tea drinking and the ris... [J Alzheimers Dis. 2009.