& Bioscience. Oming: A biological information restructuring in the way we understand ourselves and relatives. National Resource for Network Biology. The genetic code is nearly optimal for allowing additional information within protein-coding sequences. + Author Affiliations Abstract DNA sequences that code for proteins need to convey, in addition to the protein-coding information, several different signals at the same time.
These “parallel codes” include binding sequences for regulatory and structural proteins, signals for splicing, and RNA secondary structure. Here, we show that the universal genetic code can efficiently carry arbitrary parallel codes much better than the vast majority of other possible genetic codes. This property is related to the identity of the stop codons. GeneticCode.pdf (application/pdf Object) Stephen Jay Gould. Stephen Jay Gould (/ɡuːld/; September 10, 1941 – May 20, 2002) was an American paleontologist, evolutionary biologist and historian of science.
He was also one of the most influential and widely read writers of popular science of his generation. Gould spent most of his career teaching at Harvard University and working at the American Museum of Natural History in New York. In the later years of his life, Gould also taught biology and evolution at New York University. Gould's most significant contribution to evolutionary biology was the theory of punctuated equilibrium, which he developed with Niles Eldredge in 1972. The theory proposes that most evolution is marked by long periods of evolutionary stability, which is punctuated by rare instances of branching evolution.
Kodon. Sequence alignment. A sequence alignment, produced by ClustalW, of two humanzinc finger proteins, identified on the left by GenBank accession number.
Key: Single letters: amino acids. Red: small, hydrophobic, aromatic, not Y. Blue: acidic. Magenta: basic. Green: hydroxyl, amine, amide, basic. European Bioinformatics Institute. FASTA format.