CircuitsDB. A database of MicroRNA / Transcription Factor Regulatory Circuits in Human and Mouse Welcome to Circuits DB, a resource devoted to the identification and analysis of mixed MicroRNA / Transcription Factor Regulatory Circuits in the Human and Mouse genomes. Promoters and 3'-UTRs are thought to control the expression of coding genes mainly in response to transcription factors (TF) and microRNAs. In particular, several methods exist to elucidate TF-related and microRNA-related regulatory networks, but comparable information is lacking to explicitly connect them. Micro RNA measuring with UPL based technique.
The aim of technology Gene expression and translational regulation via micro RNA became well-known in the past few years.
Micro RNA was called by this name in a publication in 2002. Their significance was stressed, since the regulation opened a completely new research area when Andrew Fire and Craig Mello described the fundamental phenomenon in 1998. More methods are available to implement our research. MiRNASNP. MicroRNAs (miRNAs) are endogenous ~22 nt non-coding RNAs which play important regulatory roles in animals and plants by targeting mRNAs for cleavage or translational repression.
Some SNPs in pre-microRNAs, flanking regions or target sites have been demonstrated to affect certain physiological processes or related with diseases. The aim of miRNA related SNP database is to provide a resource of the miRNA-related SNPs, which included SNPs in human pre-miRNAs and miRNA flanks, SNPs in other species's miRNAs, and target gain and loss by SNPs in miRNA seed regions or 3'UTR of target mRNAs. Thus, Five major modules are provided in this database and users can browse or search it in different levels.
Latest miRNASNP blog: miRNASNP 2.0 is released.
Computationally predicted mRNA targets. Enabling RNA therapy. YM500.