WIREsRNA: Be sure to browse our site,... WIREsRNA : Fascinating take on how isolation... Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures. WIREsRNA : RNA Structural Motifs @eLi... WIREsRNA : Advanced Review: The Bin3... WIREsRNA : Protein–RNA footprinting... WIREsRNA : RT @WiSciBlog: Lariats: Ho... WIREsRNA : Potential pitfalls in micr... WIREsRNA: Protein–RNA footprinting... WIREsRNA : RNA in the classroom: beyo... WIREsRNA : RT @IAmBiotech: A-ma-zing:... WIREsRNA: RT @IAmBiotech: A-ma-zing:...
WIREsRNA: Antibiotics that target pr... WIREsRNA: RNA biology in a test tube... RNA biology in a test tube—an overview of in vitro systems/assays. Advanced Review Xavier Roca, Fedor V. Karginov Published Online: Mar 22 2012 DOI: 10.1002/wrna.1115 <h3>Abstract</h3> In vitro systems have provided a wealth of information in the field of RNA biology, as they constitute a superior and sometimes the unique approach to address many important questions. Such cell‐free methods can be sorted by the degree of complexity of the preparation of enzymatic and/or regulatory activity. <h3 class="article-tab-heading">Images</h3> Figure 1. Types of in vitro systems by degree of complexity.
. [ Normal View | Magnified View ] Figure 2. Pre‐mRNA processing. . [ Normal View | Magnified View ] Figure 3. Pre‐mRNA capping/decapping. . [ Normal View | Magnified View ] Figure 4. Pre‐mRNA editing. . [ Normal View | Magnified View ] Figure 5. Standard in vitro pre‐mRNA splicing assays. . [ Normal View | Magnified View ] Figure 6. Basic assays on in vitro pre‐mRNA 3′‐end formation. . [ Normal View | Magnified View ] Figure 7. An overview of eukaryotic small RNA pathways. Figure 8. WIREs RNA: MicroRNA degradation and t... WIREs RNA: G-quadruplexes in RNA biol... Twitter. Synthetic Nucleic Acids: Beyond DNA and RNA | Bio 2.0 | Learn Science at Scitable. Synthetic biology is such a wide-ranging and multi-disciplinary field that it seems like every new paper sends me into a new area of science that I hadn't considered before. The latest issue of Science features a paper1 on synthetic nucleic acids, completely new molecules capable of information storage just like DNA and RNA, dubbed xeno-nucleic acids, or XNAs.
There are lots of reasons to understand the limits of biological-or chemical-information storage. It is truly wondrous that the phenomenon exists at all; our genome is quite an awe-inspiring 46-molecule collection (for each chromosome is, at heart, an enormously long but unbroken molecule of DNA). All life, at least as we know it, uses DNA or RNA for storing and retrieving genetic information. We know for certain that DNA was not the first information storage molecule, since DNA is completely reliant on a protein copying mechanism that is far too complicated to have been present at the origin of life.
A Tangent References: Twitter. Evidence of altered RNA stirs debate. WIREs RNA: RNA decay: a novel therape... Fabrice Leclerc: RNA-Seq reveals complexity... WIREs RNA: Roles of tRNA in cell wall... WIREs Dev Bio: "The microRNA regulation o... Twitter. Twitter. WIREs RNA: The structures of nonprote... WIREs RNA: Identification of RNA–prot... Twitter. WIREs RNA: Diversity of animal small... Fabrice Leclerc: RT @SciReports: Cdc14b reg... Newscientist: DARPA wants to use small i... WIREs RNA: mRNA export and cancer ht... WIREs RNA: RNAi screening: new approa... WIREs RNA: Aging—RNA in development a... WIREs RNA: The role of RNA in mammali...
WIREsRNA: Diversity of animal small... Twitter. NatureRevGenet: AOP Highlight on a new reg... WIREsRNA: Updates on RNAi screening... Twitter. Biology Magazine: Comparative Analysis of 16... Ken Yaw Agyeman-Badu: RNA interference based res... Fabrice Leclerc: Combined #RNA Interference... WIREsRNA: RNA‐binding proteins in ne... Twitter.
PLoS ONE: Very Few RNA an. Fabrice Leclerc: Novel technique uses #RNA... WIREs RNA: Aging—RNA in development a... Fabrice Leclerc: #RNA helicases and remodel... Cell DNA: New Stanford technique giv... Plant biology: PLoS ONE 'AGO6 Functions i... WIREs RNA: RNAi screening: new approa... WIREs RNA: RNA dynamics: perspectives... Fabrice Leclerc: Top story: Competition bet... Genome Biology: Ana Conesa: Seq depth affe... EuPathDB: Nice review "Gene expressi... WIREs RNA: Small RNA and transcriptio... WIREs RNA: Transfer RNA‐derived fragm... Fabrice Leclerc: The different epidemiologi... WIREs RNA: Transfer #RNA‐derived frag... WIREs RNA: Small RNA and transcriptio... Bio-Network: Optimization of RNA isolat... WIREs RNA: Small RNA and transcriptio... Erika Check Hayden: T Yomo constructing self-r... Fabrice Leclerc: GenoSplice on Jun 20, 2011... Eureka Biology: Cooperative RNP assembly:... Eureka Biology: RNA silencing pathways of... Bot of The Cell: Editing by RNA Synthetases...
Bot of The Cell: RNA Splicing Is Performed... Fabrice Leclerc: Transient DNA/#RNA-protein... Justin H. Johnson: Full-length transcriptome... WIREs RNA: Delivery of RNAi mediators... WIREs RNA: Small RNA and transcriptio... Early View. WIREs RNA: Cryptic genetic variation... WIREs RNA: Small RNA and transcriptio... Fabrice Leclerc: plant biology on May 03, 2...
WIREs RNA: RITS—connecting transcript...