background preloader

Personalised Medicine

Facebook Twitter

European Society of Human Genetics: News. For immediate release: Thursday 16 March 2017 A Bill that would allow companies to require employees to undergo genetic testing and disclose the results to their employers, or risk having to make health insurance payments of thousands of dollars extra, was recently approved by the US House of Representatives Committee on Education and the Workforce, with all 22 Republicans supporting it and all 17 Democrats opposing.

European Society of Human Genetics: News

Genetic tests can predict health risks. In the US, where companies cover significant parts of the health insurance of their employees they may, understandably, want to minimise these risks. In the past, however, decisions on whether or not to undergo genetic testing have been the voluntary choices of individuals. GC-CANCRSC Graduate Certificate in Cancer Sciences - 2017. The Centre for Genetics Education — Centre for Genetics Education. GetSharedSiteSession?rc=4&redirect= To view the full text, please login as a subscribed user or purchase a subscription.


Click here to view the full text on ScienceDirect. Fig. 1 Schematic overview of the INFORM workflow and timelines. Tartu Ülikooli Eesti geenivaramu. Theconversation. Our Test. You are unique, your medication should be too Your unique genetic profile determines how your body processes certain medications.

Our Test

Some people process certain medications too quickly and receive little or no benefit. Others process some medications too quickly and are at and increased risk of dangerous side effects. Up to 1 in 3 people may process certain types of medications too quickly which can increase the risk of treatment failure 1 Up to 1 in 10 people may process certain types of medications too slowly which can increase the risk of side effects 2 Why take the test The myDNA Medication test can help your doctor personalise your treatment by selecting the medications and doses that may work with you. Chemmart agrees to improve its promotion of “myDNA” tests. The Australian Competition and Consumer Commission has accepted an administrative undertaking on behalf of Chemmart in relation to representations regarding the effectiveness of a myDNA genetic test in identifying an individual’s response to certain drugs.

Chemmart agrees to improve its promotion of “myDNA” tests

The ACCC was concerned that statements in Chemmart’s catalogues, television infomercials, in-store brochures and other promotional materials about the myDNA test risked conveying a false or misleading impression regarding the usefulness of the genetic test, and the consumers for whom it may be appropriate. A person’s genetic profile is just one of a wide range of factors that may be considered by a medical practitioner in determining the type and dose of drug that is suitable for an individual.

“Consumers place a high level of trust in pharmacists and the information they provide. Chemmart withdrew all of the promotional materials containing the statements of concern to the ACCC following contact by the ACCC. Background. The National Academies Press. 'Customized Care' MyDNA. Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies. Abstract Background.

Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies

Precision Medicine Is A Needed Goal That Will Benefit Cancer Patients. Since last month’s post on precision medicine in oncology, Americans continue to worry about prescription drug costs, a poll confirmed.

Precision Medicine Is A Needed Goal That Will Benefit Cancer Patients

Most cancer meds approved by the FDA in recent years don’t extend life but do cost more, a JAMA study found. These indicators – along with news that “miracle” drugs remain unlikely to be truly miraculous – take us back to the question of whether precision medicine is a valid goal. Today an oncologist-policy-maker-and-medical-ethicist reminds us that, in effect, we’re all paying for the sky-high price of new drugs. Which begs the question, if patients – or society – can’t afford the cancer treatments we’ve already got, why search for new ones? My bottom line: Precision medicine will help cancer patients.

Take it to another level: Precision Medicine (PM) will emerge as a positive industry encompassing science, informatics and health care delivery. No doubt, progress is imperfect. Database Access - UNSW Library. NUS Engineering team develops novel technology to “print” customised tablets for personalised medicine. A team of researchers from the National University of Singapore (NUS) have found a way to make personalised medicine cheaper and easier.

NUS Engineering team develops novel technology to “print” customised tablets for personalised medicine

Imagine if you could combine the myriad of pills you need to take for your ailment in just one tablet; or if you need only to take the medication once a day and the drug will be slowly released throughout the day at different rates to treat your illness; or if doctors could easily make tablets on the spot that are tailored to each patient’s needs. All these could become a reality with a new method of tablet fabrication designed by Assistant Professor Soh Siow Ling and PhD student Ms.

Sun Yajuan from the Department of Chemical and Biomolecular Engineering at the NUS Faculty of Engineering. The novel system can make customisable pills that release drugs with any desired release profiles. Customised tablets for optimal therapeutic results Releasing drugs in a timely manner is important for optimal therapeutic effect in the human body. Untitled. As we find out more about our genes and how we react differently to diseases and to treatment, personalised medicine becomes increasingly important.


Genomic medicine is the use of genomic information in clinical decision-making and patient care. This type of personalised medicine can be used to support more accurate diagnosis and prognosis, to identify patients at a greater risk of disease or complications, to select and prioritise therapy and in the prevention and control of outbreaks of infections. Murdoch Childrens has always been at the forefront of genetics and, using in-house genetic technologies, our researchers have been able to discover many new disease genes.

Gene discovery is the first step towards developing effective treatments. However, whilst this technology is being used in a research laboratory setting, these dramatic advances in genomic research are not yet routinely available in the clinical setting. AGRF. Genomics: National Insights of Australians. Database Access - UNSW Library. Pharmacogenetics and Stratified Medicine MSc. The Dr. John T. Macdonald Foundation Department of Human Genetics at Miller School of Medicine. Overview Congratulations to the 2015 MD/MS Genomic Medicine students Be a part of the future of genomic and personalized medicine!

The Dr. John T. Macdonald Foundation Department of Human Genetics at Miller School of Medicine

This 4-year concurrent master’s degree in Genomic Medicine will provide you with the background, knowledge, and understanding to integrate the ever expanding field of genomics into your practice. No matter which medical specialty you choose, genomic medicine is increasingly becoming an integral part of patient care with the use of predictive clinical sequencing, pharmacogenetics, and whole genome analysis. Educational Mission of the MD/MS Program in Genomic Medicine The educational mission of the program is to graduate clinicians with the ability to integrate genomic knowledge into their clinical practice. The MD/MS degree program in Genomic Medicine will provide: UCSF Steps Forward to Lead Advances in Precision Medicine. UC San Francisco convened 170 of the world’s foremost thinkers, creators and innovators last month at the OME Precision Medicine Summit to identify new approaches and spur action to make medicine more predictive, preventive and precise.

UCSF Steps Forward to Lead Advances in Precision Medicine

Now, the ideas generated at the summit in May are moving ahead across the University and the nation as part of many focused efforts to make precision medicine a reality. The promise of precision medicine – the next revolution in health – is described by leaders, including Francis Collins, MD, PhD, director of the National Institutes of Health, in a newly released four-minute video highlighting the urgent need to fundamentally transform the practice of medicine to improve health and save lives. The name OME comes from the suffix -ome, which in biology is used to connote a totality of precise elements and their interrelationships. Thus the entirety of a person’s genes forms a genome, proteins form the proteome, microbes form the microbiome. Pharmacogenomics and Personalised Health Care (PHAR4201) / Course / The University of Newcastle, Australia. This course uses the cognitive and technical skills in molecular medicine and pharmacogenomincs learnt over the program to discuss advanced molecular basis of altered health states and drug response.

TEDMED - Home. Theconversation. Drink red wine to prevent cancer. But don’t drink too much! Get some exercise. But don’t overdo it. Targeted Agent & Profiling Utilization Registry Study (TAPUR) NCI-Molecular Analysis for Therapy Choice Program (NCI-MATCH) The Trial NCI-Molecular Analysis for Therapy Choice (NCI-MATCH) is a clinical trial that will analyze patients’ tumors to determine whether they contain genetic abnormalities for which a targeted drug exists (that is, “actionable mutations”) and assign treatment based on the abnormality. NCI-MATCH seeks to determine whether treating cancers according to their molecular abnormalities will show evidence of effectiveness. NCI-MATCH can add new treatments or drop treatments over time.

Each treatment will be used in a unique arm, or substudy, of the trial. Mayo Clinic to Study 10,000 Patients for Drug-Gene Safety. Posted by Jeff Briggs (@jeffbriggs) · 2 day(s) ago Mayo Clinic to Study 10,000 Patients for Drug-Gene Safety Today, we have exciting news from the Center for Individualized Medicine. We suspected something was up when we heard Dr. Weinshilboum walking through the halls humming the Bob Dylan folk anthem “The Times They Are a Changin’.”

If you care about precision medicine and the role pharmacogenomics plays in the future of health care, they are changing indeed. The following story was announced this week. “Why Do We Have to Learn This Stuff?”—A New Genetics for 21st Century Students. Citation: Redfield RJ (2012) “Why Do We Have to Learn This Stuff?” —A New Genetics for 21st Century Students. PLoS Biol 10(7): e1001356. doi:10.1371/journal.pbio.1001356 Series Editor: Cheryl A. Mayo Clinic to Study 10,000 Patients for Drug-Gene Safety. NYU CENTER FOR HEALTH INFORMATICS AND BIOINFORMATICS. Editorial Virtual Special Issue: Health Behavior Change. DCCPS: Health Behavior Constructs: Theory, Measurement, & Research. Integrated Theory of Health Behavior Change. Collins and Varmus Outline Potential of Precision Medicine Initiative in NEJM Perspective. Clinical Pharmacology & Therapeutics - Volume 95 Supply Chain Management & Personalized Medicine - February 2014.

Clinical Pharmacology & Therapeutics - Volume 94 Genomic Medicine - August 2013. Hepatitis C (chronic) - sofosbuvir [ID654] Hepatitis C (chronic) - sofosbuvir [ID654] NICE consults on further draft guidance on the drug sofosbuvir (Sovaldi) for treating hepatitis C. Hepatitis C is a virus that infects the liver. It is spread by contact with infected blood, for instance by using contaminated needles for injecting drugs or sharing razors or toothbrushes. The virus can cause inflammation of, and damage to the liver, preventing it from working properly. Although 15 to 20% of people infected with the hepatitis C virus naturally clear their infections within 6 months, the remainder develop chronic hepatitis which can be life-long.

Figures from 2012 suggest that around 160,000 people are chronically infected with the hepatitis C virus in England. More than half of people with chronic hepatitis C do not know they are infected because they only have mild symptoms or no symptoms at all for a long period of time. About 1 in 3 people infected with the hepatitis C virus will eventually develop liver cirrhosis, where normal liver tissue is replaced by scar tissue. A small percentage of people with chronic hepatitis C and cirrhosis also develop liver cancer. Ends 13. Pharmacogenetics, Pharmacogenomics, and Individualized Medicine. David R. VEGF and EGFR pathways in detail: Target for new therapies against cancer. Epidermal growth factor receptor EGFR Tyrosine kinase. Higher Education. Marks-Clerk-Life-Sciences-Report-2014.pdf. Social Media Push to Get Experimental Drugs on the Rise. <br/><a href=" more news videos</a> | <a href=" from the US</a>

Bowing to public outrage, pharma company to give dying boy experimental drug. Josh Hardy Going Home After Getting Chimerix Anti-Viral Drug. Genes and inheritance. Learn Genetics. Resources, Animations, Interviews, + Tools. We are enhancing our most popular resources by building collections around them. First up: Polymerase Chain Reaction! The DNA Learning Center has been developing multimedia animation programs since 1990. These popular programs feature some of the most common molecular processes such as PCR, sequencing, and DNA restriction. View online or download for play from your computer. Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests: Workshop Summary.

Genomics > Table of Pharmacogenomic Biomarkers in Drug Labeling. Personalized Medicine. Genetics Home Reference - Your guide to understanding genetic conditions. Walter and Eliza Hall Institute of Medical Research. DNA sequencing is becoming faster and more sophisticated, making it easier to determine the best treatment based on genetics of the disease and the individual. Personalized Medicine and You - The Jackson Laboratory.

Genomic testing paves way for personalised medicine. Becky Harvey is diagnosed with Syndrome Without a Name. Source: News Limited. Ucm372421.pdf. Personalized Medicine Coalition.