Category:Devices to alter consciousness. Category:Mind control theorists. Insulin Therapy for Schizophrenia. Feedback about this article? Reliable statistics are mostly in favour of the value of the treatment. In a series of over 400 patients treated in Swiss hospitals before 1937, when the technique was still new, 59 per cent. of persons treated within the first six months after onset reached either a complete or social remission. In the New York State hospitals of over a thousand schizo- phrenics treated with insulin 11.1 per cent. recovered, 26.5 per cent. made great improvement, and 26 per cent. some improvement; the corresponding figures in over a thousand control patients were 3.5 per cent., 11.2 per cent. and 7.4 per cent. A comparable number of patients treated with cardiazol convulsion therapy did not do even as well as the control patients. Furthermore, the treatment greatly shortens the duration of the illness.
The results are much more favourable when treatment is given early. The risks of treatment are in general less than the risks of waiting for spontaneous remission to occur. AIM25 text-only browsing: Wellcome Library: Sargant, William Walters (1907-1988) Graphical version Sargant, William Walters (1907-1988) Reference code(s): GB 0120 PP/WWS Held at: Wellcome Library Title: Sargant, William Walters (1907-1988) Date(s): c1920s-1987 Level of description: Collection (fonds) Extent: 21 boxes Name of creator(s): Sargant | William Walters | 1907-1988 | psychiatrist Administrative/Biographical history: Scope and content/abstract: Sargant was an outspoken supporter and practitioner of what he termed the 'practical rather than philosophical approaches' to the treatment of mental illness, pioneering and publicising various physical treatments and vociferously opposing the use of psychoanalytic techniques.
Language/scripts of material: English System of arrangement: By section as follows: A. Dr Dally reported that the material was in considerable disarray on arrival at her home and she subsequently grouped the majority of the papers into categories by subject, most of these representing either medical conditions or methods of treatment. Finding aids: Accruals: Pentylenetetrazol. Pentylenetetrazol (INN), also known as pentylenetetrazole, metrazol, pentetrazol, pentamethylenetetrazol, Cardiazol or PTZ, was a drug used as a circulatory and respiratory stimulant. High doses cause convulsions, as discovered by the Hungarian-American neurologist and psychiatrist Ladislas J.
Meduna in 1934. It has been used in convulsive therapy, but was never considered to be effective, and side-effects such as seizures were difficult to avoid. Its approval by the FDA was revoked in 1982.[1] Mechanism[edit] The mechanism of pentylenetetrazol is not well understood, and it may have multiple mechanisms of action. In 1984, Squires et al. published a report analyzing pentylenetetrazol and several structurally related convulsant drugs. Several studies have focused on the way pentylenetetrazol influences neuronal ion channels. Uses[edit] Pentylenetetrazol has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.