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New Cancer Therapies

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Chemotherapy regimens. Chemotherapy drugs are natural, semisynthetic, or synthetic substances with selective inhibitory effects against biological pathogenic agents (microorganisms) of humans and animals and against atypical (cancerous) cells. The majority of chemotherapeutic drugs can be divided into antifungal agents, antiprotozoal, antimicrobial, antitubercular, antileprotic, antihelmintic, antiviral, cytostatic, and other agents.

A fundamental philosophy of oncological combination chemotherapy is that different chemotherapy drugs work through different cytotoxic mechanisms, and that the results of using multiple drugs will be synergistic to some extent. Because they have different dose-limiting adverse effects, they can be given together at full doses in chemotherapy regimens.[1] The term "induction regimen" refers to a chemotherapy regimen used for the initial treatment of a disease. Chemotherapy regimens are often identified by acronyms, identifying the agents used in the drug combination. See also[edit] Human medicines - Medicines under evaluation.

T Cells

Clinical trial raises hope for cancer treatment - latimes.com. A microscopic image shows two T cells binding to beads, depicted in yellow,… (Dr. Carl June / Penn Medicine ) In a potential breakthrough in cancer research, scientists at the University of Pennsylvania have genetically engineered patients' T cells — a type of white blood cell — to attack cancer cells in advanced cases of a common type of leukemia. Two of the three patients who received doses of the designer T cells in a clinical trial have remained cancer-free for more than a year, the researchers said.

Experts not connected with the trial said the feat was important because it suggested that T cells could be tweaked to kill a range of cancers, including ones of the blood, breast and colon. "This is a huge accomplishment — huge," said Dr. Lee M. Findings of the trial were reported Wednesday in two journals. To build the cancer-attacking cells, the researchers modified a virus to carry instructions for making a molecule that binds with leukemia cells and directs T cells to kill them.

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