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Benaroya Research Institute at Virginia Mason (BRI) received a $7 million contract from the National Institutes of Health (NIH) to study cell responses and efficacy of vaccines for several well-known and exotic viruses, including influenza (seasonal and H1N1 "swine flu"), West Nile, Dengue fever, Japanese encephalitis (JEV) and yellow fever. West Nile, Dengue, JEV and yellow fever, also known as flaviviruses, are among the leading causes of mortality and morbidity worldwide. The five-year study will use BRI's tetramer technology to identify virus components that are targeted by T-cells following infection and vaccination. "The goal here is to identify and ensure the most effective vaccines are being produced, and ultimately lead to new vaccines for viruses such as Dengue and West Nile," said William Kwok, PhD, principal investigator for the contract and BRI faculty member.

