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A new study points to a conceptually novel therapeutic strategy for treating depression. Instead of dampening neuron firing found with stress-induced depression, researchers demonstrated for the first time that further activating these neurons opens a new avenue to mimic and promote natural resilience. The findings were so surprising that the research team thinks it may lead to novel targets for naturally acting antidepressants. Boosting depression-causing mechanisms in brain increases resilience, surprisingly | Boosting depression-causing mechanisms in brain increases resilience, surprisingly |
Just 1 Rock Concert or Football Game May Cause Permanent Hearing Damage | Talking back A single exposure to loud but not deafening noise may be enough to precipitate irreparable harm to nerves in the auditory system. This is the take-home from a new line of research that may help explain why many people, particularly as they age, have difficulty in picking out a conversation from the wall of background noise that is a requisite accompaniment to any football game or meal at a family-style restaurant. Studies over the past five years in animals—with some evidence now coming from human research—are starting to overturn conventional wisdom about hearing loss. It was previously thought that the downside of exposure to the raucous sounds of an afternoon sporting event might do nothing more than leave you with the sensation that your ears were filled with cotton for a while, but then hearing would more or less return to normal. Just 1 Rock Concert or Football Game May Cause Permanent Hearing Damage | Talking back
Trauma can be inherited from parents
Breakthrough therapy allows four paraplegic men to voluntarily move their legs Breakthrough therapy allows four paraplegic men to voluntarily move their legs Four young men who have been paralyzed for years achieved groundbreaking progress—moving their legs—as a result of epidural electrical stimulation of the spinal cord, an international team of life scientists reports today in the medical journal Brain. The study, conducted by researchers from the University of Louisville, UCLA and the Pavlov Institute of Physiology, was funded in part by the Christopher and Dana Reeve Foundation and the National Institutes of Health. All four participants were classified as suffering from chronic, motor complete spinal cord injuries and were unable to move their lower extremities prior to the implantation of an epidural stimulator.
STAP cells, glowing green, have been integrated into the mouse fetus’s body tissues. Credit: Haruko Obokata Researchers have observed that plants, when stressed, can reprogram their cells into stem cells, capable of differentiating into many different cell types. Now, it appears mammals can perform the same trick. New Method of Creating Stem Cells is a "Game Changer" - D-brief | New Method of Creating Stem Cells is a "Game Changer" - D-brief |
Does Evolution Evolve Under Pressure? - Wired Science In 1996, Susan Rosenberg, then a young professor at the University of Alberta, undertook a risky and laborious experiment. Her team painstakingly screened hundreds of thousands of bacterial colonies grown under different conditions, filling the halls outside her lab with tens of thousands of plates of bacteria. “It stank,” Rosenberg recalled with a laugh. “My colleagues hated me.” The biologist, now at Baylor College of Medicine in Houston, hoped to resolve a major debate that had rocked biology in different incarnations for more than 100 years. Were organisms capable of altering themselves to meet the needs of their environment, as Jean Baptiste Lamarck had proposed in the early 1800s? Does Evolution Evolve Under Pressure? - Wired Science
Malcolm Gladwell: Do Genetic Advantages Make Sports Unfair? Malcolm Gladwell: Do Genetic Advantages Make Sports Unfair? Toward the end of “The Sports Gene” (Penguin/Current), David Epstein makes his way to a remote corner of Finland to visit a man named Eero Mäntyranta. Mäntyranta lives in a small house next to a lake, among the pine and spruce trees north of the Arctic Circle. He is in his seventies. There is a statue of him in the nearby village. “Everything about him has a certain width to it,” Epstein writes. “The bulbous nose in the middle of a softly rounded face.
Longevity Gene: Discovery opens the door to a potential 'molecular fountain of youth' Longevity Gene: Discovery opens the door to a potential 'molecular fountain of youth' A new study led by researchers at the University of California, Berkeley, represents a major advance in the understanding of the molecular mechanisms behind aging while providing new hope for the development of targeted treatments for age-related degenerative diseases. Older and fitter? New findings from a UC Berkeley-led study could have implications for the development of treatments for age-related degenerative diseases.
Photo: Bukowsky18 (CC) [disinfo ed.'s note: this original essay was first published by disinformation on May 14, 2001. Some links and contact information may have changed.] A worldwide epidemic is raging. The cause is a poisonous chemical sweetener, aspartame (marketed as NutraSweet, Equal, Spoonful), the most controversial food additive ever approved. The Aspartame Epidemic The Aspartame Epidemic
MIT and Hong Kong University researchers have shown that some simple biodegradable liquids can stop bleeding in wounded rodents within seconds, a development that could significantly impact medicine. When the liquid, composed of protein fragments called peptides, is applied to open wounds, the peptides self-assemble into a nanoscale protective barrier gel that seals the wound and halts bleeding. Once the injury heals, the nontoxic gel is broken down into molecules that cells can use as building blocks for tissue repair. material stops bleeding in seconds material stops bleeding in seconds
Profits over your dead body Imagine living in a world where visiting the doctor was an experience fraught with danger. Where the drugs you were prescribed may or may not be effective—and may or may not be safe. Imagine having a medical procedure recommended that wasn't known to work. Up until the beginning of the 20th century, that was the case. Profits over your dead body
Drug research: Toxic medicine
Penn Medicine News: One Shot of Gene Therapy and Children with Congenital Blindness Can Now See PHILADELPHIA – Born with a retinal disease that made him legally blind, and would eventually leave him totally sightless, the nine-year-old boy used to sit in the back of the classroom, relying on the large print on an electronic screen and assisted by teacher aides. Now, after a single injection of genes that produce light-sensitive pigments in the back of his eye, he sits in front with classmates and participates in class without extra help. In the playground, he joins his classmates in playing his first game of softball. His treatment represents the next step toward medical science’s goal of using gene therapy to cure disease. Extending a preliminary study published last year on three young adults, the full study reports successful, sustained results that showed notable improvement in children with congenital blindness.
Athletes and arthritics rejoice: Wake Forest researchers have combined low-cost cell printing and electrospinning to create implantable cartilage. Photo courtesy IOP Publishing. Scientists at the Wake Forest Institute of Regenerative Medicine have pioneered an approach to replace damaged cartilage, combining two low-cost techniques. That’s right. We have the ability to 3-D print human cartilage. Hybrid 3-D Printer Used to Create Cartilage Implants | Wired Design
11.19.2007 - New technique captures chemical reactions in a single living cell for the first time UC Berkeley Press Release New technique captures chemical reactions in a single living cell for the first time By Sarah Yang, Media Relations | 19 November 2007 BERKELEY – Bioengineers at the University of California, Berkeley, have discovered a technique that for the first time enables the detection of biomolecules' dynamic reactions in a single living cell.
BioFuel Cell Uses Glucose in the Body to Produce Electricity for Cyborgs Biofuel cells turned glucose into electricity in rats. Researchers at Joseph Fourier University in France have created a new biofuel cell that harnesses oxygen and glucose from the body to produce electricity. Glucose biofuel cells (GBFCs) were placed inside the bodies of rats, and displayed peak energy densities of 24.4 microwatts per milliliter – better than many pacemaker batteries. Glucose and oxygen flow into the fuel cell, and waste products flow out, but the enzymes and metals inside don’t contiminate the body. The work was detailed in a paper published in PLoS. The JFU team hopes that a new generation of GBFCs will be able to power all kinds of implants in humans.
Does The Family Really Need Lipitor and Aspirin? - | Some things won’t change this year. I’ll still be a bald, tattoo sporting chemist who sings rap music too loud while driving. My kids will still know more about the benefits of individualism over collectivism than most adults. And many people will blindly think that they need to lower their cholesterol with Lipitor (or any other cholesterol-lowering alternative) to save them from heart attack and stroke. The myth is so prevalent that The American Academy of Pediatrics and The American Heart Association issued new guidelines set out to put children as young as 8 years old on cholesterol-lowering drugs (statins).
Tricks Foods Play
Tough gel stretches to 21 times its length, recoils, and heals itself: Biocompatible material much tougher than cartilage
researchers' cooling glove 'better than steroids'
Dr. Karl Jansen
UC Davis News & Information :: Chemical widely used in antibacterial hand soaps may impair muscle function
Common parasite may trigger suicide attempts: Inflammation from T. gondii produces brain-damaging metabolites
Scientists can now block heroin, morphine addiction
Roid Age: the paradox of pharmacological puritanism | Neuroanthropology
Injecting life-saving oxygen into a vein
Early gut bacteria regulate happiness
MIT Develops a Magnetic Hypospray for Needleless Shots
The Beating Heart Donors | Health & Medicine
The Gruesome History of Eating Corpses as Medicine | History & Archaeology
Cancer 'cure' in mice to be tested in humans
Nathan Wolfe's jungle search for viruses
New View of Depression: An Ailment of the Entire Body
Data mining opens the door to predictive neuroscience
Genetic 'Light Switches' Control Muscle Movement
Alana B. Elias Kornfeld: TEDMED 2009: Using Sleep As A Gateway Into The Brain
Tyrone Hayes + Penelope Jagessar Chaffer: The toxic baby?
Bill Doyle: Treating cancer with electric fields
Why do cells age? Discovery of extremely long-lived proteins may provide insight into cell aging and neurodegenerative diseases
Babies with three parents possible within three years
Cold Plasma Kills Bacteria Better Than Antibiotics
New bandage spurs, guides blood vessel growth
Deep-Brain Stimulation Found to Fix Depression Long-Term
New 'smart' material could help tap medical potential of tissue-penetrating light
Cynthia Kenyon: Experiments that hint of longer lives
How Your Brain Could Fix Your Diabetes
10 High-Tech Health Breakthroughs Coming Soon to Your Body