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Requirements for an accurate null model An optimal null model preserves all the features of the original data with the exception of the signal under question that needs to be removed efficiently. In our case, the data are multiple alignments of homologous sequences and the signal of interest is an evolved RNA secondary structure.
Abstract
“Recognizing a Stem-Loop Structure: Metazoan histone messenger RNAs (mRNAs) have a conserved stem-loop... # science #AAAS”