Interesting molecules
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An entheogen ("generating the divine within") [ 4 ] is a psychoactive substance used in a religious , shamanic , or spiritual context. [ 5 ] With the advent of organic chemistry , there now exist many synthetic substances with similar psychoactive properties, many derived from these plants. Entheogens can supplement many diverse practices for healing, transcendence , and revelation , including: meditation , psychonautics , art projects, and psychedelic therapy . Entheogens have been used in a ritualized context for thousands of years; their religious significance is well established in anthropological and modern evidences.
Psilocybin [ nb 1 ] ( / ˌ s ɪ l ə ˈ s aɪ b ɪ n / SIL -ə- SY -bin ) is a naturally occurring psychedelic compound produced by more than 200 species of mushrooms , collectively known as psilocybin mushrooms . The most potent are members of the genus Psilocybe , such as P. azurescens , P. semilanceata , and P. cyanescens , but psilocybin has also been isolated from about a dozen other genera . As a prodrug , psilocybin is quickly converted by the body to psilocin , which has mind-altering effects similar to those of LSD and mescaline . The effects generally include euphoria , visual and mental hallucinations , changes in perception , a distorted sense of time , and spiritual experiences, and can include possible adverse reactions such as nausea and panic attacks . Imagery found on prehistoric murals and rock paintings of modern-day Spain and Algeria suggest that human usage of psilocybin mushrooms dates back thousands of years.
Psilocin ( 4-HO-DMT ), an aromatic compound, sometimes also (mis)spelled psilocine , psilocyn , or psilotsin , is a psychedelic mushroom alkaloid . It is found in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin . Psilocin is a Schedule I drug under the Convention on Psychotropic Substances . [ 1 ] The mind-altering effects of psilocin are highly variable and subjective, but resemble those caused by LSD and mescaline .
Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors . These include the endocannabinoids (produced naturally in the body by humans and animals), [ 1 ] the phytocannabinoids (produced by various plants), and synthetic cannabinoids (produced chemically by man). The most notable cannabinoid is the phytocannabinoid ∆ 9 - tetrahydrocannabinol (THC), the primary psychoactive compound of cannabis. [ 2 ] [ 3 ] However, there are known to exist numerous other cannabinoids with varied effects. Synthetic cannabinoids encompass a variety of distinct chemical classes: the classical cannabinoids structurally related to THC, the nonclassical cannabinoids (cannabimimetics) including the aminoalkylindoles , 1,5-diarylpyrazoles , quinolines , and arylsulphonamides , as well as eicosanoids related to the endocannabinoids. [ 2 ] [ edit ] Cannabinoid receptors
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32 mg·kg −1 (Maus i.v. ) [3] Soweit möglich und gebräuchlich, werden SI-Einheiten verwendet. Wenn nicht anders vermerkt, gelten die angegebenen Daten bei Standardbedingungen .