UCDAVIS 27/08/20 Amazon and Congo Basin Focus of New Emerging Infectious Disease Research Center - $8M to UC Davis to Investigate Viral Emergence and Spillover in Vulnerable Forest Regions. OUVRAGE EN LIGNE - 2020 - Emerging and reemerging viral pathogens. GLOBAL ECOLOGY ANE BIOGEOGRAPHY 19/12/19 Distinct spread of DNA and RNA viruses among mammals amid prominent role of domestic species. Pathogen spillover and cross‐species transmission between animals and humans is a major source of infectious diseases and a considerable global public health burden (Jones et al., 2008; Karesh et al., 2012). Understanding the factors that enable or facilitate these processes is a crucial step for such events to be predicted. Host shifting, that is the colonization of a new host species by a pathogen, requires a certain level of overlap in species traits (“ecological fitting”) in order to overcome barriers of cross‐species transmission and for survival and reproduction within novel host species (Agosta, Janz, & Brooks, 2010; Parrish et al., 2008; Woolhouse, Haydon, & Antia, 2005).
Nevertheless, despite important advances in virus discovery and analytical approaches, our understanding of virus sharing and their spread through entire networks of mammalian host species remains limited. 2.1 Virus–host data 2.2 Mammalian host phylogeny and ecological trait data 2.3 Statistical analysis. ELIFE 09/06/16 Evidence of human infection by a new mammarenavirus endemic to Southeastern Asia. BIORXIV 10/05/20 Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses. GLOBALIZATION AND HEALTH 08/02/17 Global research trends of World Health Organization’s top eight emerging pathogens. OPEN FORUM INFECTIDOUS DISEASES 22/04/20 Bioaerosol Sampling at a Live Animal Market in Kunshan (China): A Noninvasive Approach for Detecting Emergent Viruses. THE ROYAL SOCIETY 08/04/20 Global shifts in mammalian population trends reveal key predictors of virus spillover risk. 1. Introduction Infectious diseases that originate from animals and infect people comprise the majority of recurrent and emerging infectious disease threats and are widely considered to be one of the greatest challenges facing public health [1–3].
Characterization of pathogen transmission events from wildlife to humans remains an important scientific challenge hampered by pathogen detection limitations in wild species. Disease spillover is probably vastly under-reported, particularly in remote regions where people have limited access to healthcare. Zoonotic disease spillover events are also difficult to detect, especially if the disease spectrum includes mild or non-specific symptoms, or if there is limited to no human-to-human transmission. The synthesis of epidemiological and ecological profiles of viruses and their hosts has enabled the detection of intrinsic virus and host features linked to species propensity to share viruses with humans [5,8]. 2. (b) Statistical analysis 3. 5. WIKIPEDIA - List of biosafety level 4 organisms.
List of organisms that require handling with the most severe protocol Biosafety level 4 laboratories are used for diagnostic work and research on easily transmitted pathogens which can cause fatal disease. What follows is a list of organisms that require handling with the most severe protocol. Organisms include those harmful to human health, to animal health, or to plant health. The Plant Protection and Quarantine programs (PPQ) of the Animal and Plant Health Inspection Service (APHIS) are listed in 7 CFR Part 331. The Department of Health and Human Services (HHS) lists are located at 42 CFR Part 73.3 and 42 CFR Part 73.4. The USDA animal safety list is located at 9 CFR Subchapter B. Select agents HHS human threats: select agents and toxins HHS human or animal threats: select agents and toxins USDA select agents and toxins PPQ select agents and toxins References
WIKIPEDIA - Emergent virus. Virus that has recently displayed increased pathogenicity or contagion, or has appeared in a new host species left no distinct epidemiological cluescould not be isolated or propagated in culture Zoonosis Zoonosis – i.e. the spread of infectious disease from animals to humans – is estimated to account for 6 out of 10 infectious diseases in humans.
Viruses (and prions) play a disproportionately large role, and account for approximately 43% of emerging (and re-emerging) human pathogens. As there is little to no occurrence of spontaneous new virus species development, the ability of a virus to ‘jump’ from its natural host is crucial during the establishment of emergent viral diseases. In order to overcome host-range restrictions and to sustain efficient human-human transmission, viruses originating from an animal reservoir frequently undergo mutation and genetic recombination. Why do viruses emerge? Environmental changes Other factors Virulence of emerging viruses VIRUSES 12/10/19 Nosocomial Transmission of Emerging Viruses via Aerosol-Generating Medical Procedures. Received: 5 September 2019 / Revised: 1 October 2019 / Accepted: 3 October 2019 / Published: 12 October 2019 Round 1 Reviewer 1 Report This review deals with a subject interesting and still topical: the risk of nosocomial transmission of viral infections through aerosol-generating medical procedures (AGMPs) in particular to healthcare workers (HCWs) attending infected patients.
The main aim of this review is to investigate which AGMPs and which viruses are most at risk. As for viruses, the authors focus on emerging viruses highly pathogenic, for which there are limited prophylactic or therapeutic countermeasures. The results reported are based on some, limited, bibliographic citations. As previously stated, the literature citations in support of the content of this review are scarce either in the section of the manuscript concerning the emerging viruses and their transmissibility by aerosol and in the last part in the section 4 concerning designing experiments and assessing risk.
Aron J. VIRUSES - MARS 2020 - Special Issue "Emerging Viruses: Surveillance, Prevention, Evolution and Control"- Deadline for manuscript submissions: 15 September 2020. Dear Colleagues, Emerging viruses represent a major concern for public health offices. Climate changes, the international migration of people and products, deforestation, and other anthropogenic activities (and their consequences) seem to be closely related to the emerging of new viruses, triggering an increasing number of notified outbreaks, epidemics, and pandemics. In this Special Issue, we encourage colleagues to submit manuscripts related to the surveillance, detection, and evolution of emerging viruses, describing from local outbreaks to worldwide viral pandemics.
We also welcome manuscripts describing new methods and technologies adapted or created for the study, prevention, and control of emerging viruses. Prof. Manuscript Submission Information Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Please visit the Instructions for Authors page before submitting a manuscript. Neurological Research and Practice 11/06/19 Emerging and re-emerging viruses affecting the nervous system.
The increased trade, travel habits, urbanization and climate change are some of the factors, which favour evolution and spread of new pathogens. Infectious diseases are emerging or re-emerging every year. Neuroinfectious diseases may occur as outbreaks in small localized regions or may spread rapidly over large geographical areas. An epidemic occurs when an infectious disease spreads rapidly to many people like the Zika Virus outbreak.
A pandemic is a global disease outbreak as seen e.g. in HIV/AIDS. Recent outbreaks caused by Chikungunya-virus, West – Nile-virus, Enterovirus infection and Ebolavirus have caused severe neurological manifestations and spread rapidly across continents. Endemic diseases are constantly present, usually in low numbers. Neurotropic viruses can access the brain via retrograde axonal transport, haematogenous spread crossing the blood-brain-barrier (BBB) or through spread of infected leukocytes across the BBB into the brain parenchyma. Epidemiology Diagnosis. MICROORGANISMS - Special Issue "Recent Advances in Antivirals for Emerging Viruses" - Deadline for manuscript submissions: 31 October 2020.
Special Issue Editors Dr. Keivan ZandiWebsiteGuest Editor Emory University, USAInterests: Antiviral Research (Intracellular and molecular mechanism study) Arbovirology Molecular virology Natural Products for Drug Discovery Infectious Disease Molecular Epidemiology Cancer Research (Intracellular and molecular mechanism study) Dr. Emory University School of Medicine, Atlanta, United States Special Issue Information Dear Colleagues, The emergence of Covid-19 is a reminder that new transmissible viruses have a potential global social, health, and economic impact. 1) direct acting antivirals; 2) modifiers of immune activation; 3) inhibitors of specific cell activation pathways. Dr. Manuscript Submission Information Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers).
Keywords. JOURNAL OF MEDICAL VIROLOGY 21/01/20 Global health concerns stirred by emerging viral infections. FRONT. VET. SCI. 24/03/20 Editorial: Emerging Swine Viruses. Over the last 30 years, diseases caused by emerging swine viruses (ESV) have acquired great relevance, more than in other species. Diseases caused by porcine reproductive and respiratory syndrome virus (PRRSv), high pathogenicity porcine epidemic diarrhea virus (PEDv), porcine circovirus type 2 (PCV-2), and influenza virus H1N1pdm09 had great economic impact. Others, however, such as porcine enteroviruses, porcine toroviruses (PToV), porcine sapelovirus (PSV), porcine bocavirus (PBoV), porcine kobuvirus (PKBV), and porcine Torque teno sus virus (TTSuV) are mostly subclinical in swine herds. Furthermore, novel emerging viruses, such as SENECA virus, atypical porcine pestivirus (APPV), PCV-3, SADS-CoV, influenza D, and others with regional or worldwide distribution constitute a new challenge for researchers and practicing veterinarians.
Emerging viruses should be considered to occur when there are changes in the relationship between the agent, the host and the enviroment. Review Articles. BIORXIV 20/03/20 Scientometric Trends for Coronaviruses and Other Emerging Viral Infections. VIRUSES - MARS 2020 - Special Issue "Emerging Viruses: Surveillance, Prevention, Evolution and Control" Health Sciences: An Open Access Peer Reviewed E-Journal. 2012 PRIORITIES AND FUTURE OF DIAGNOSIS OF EMERGING VIRAL DISEASES. INTECH - JANV 2020 - The Emerging Challenges in Transmission and Detection of Filovirus Infections in Developing Countries. 1. Introduction The filovirus infections are emerging new infections, which pose serious public health threats of global dimensions. This filovirus family comprises mainly of the Ebola virus and the Marburg virus. Some five species of Ebola have been confirmed and includes the Zaire Ebola virus (EBOV), the Sudan subtype (SUDV), the Bundibugyo virus (BDBV), the Tai Forest virus (TAFV), and the Reston virus (RESTV) [1, 2].
Most of the outbreaks have been caused by EBOV and SUDV infections. The TAFV has caused single causality. RESTV is associated with asymptomatic infection among nonhuman primates and pigs . The Marburg virus was first isolated in 1967 when laboratory workers in Marburg, Germany and Yugoslavia were infected when exposed to imported green monkeys from Uganda [4, 5]. The Ebola virus was first identified in 1976 in a major outbreak in 1976. 2. The natural history of filoviruses remains rudimentary and largely not well understood. 3. 4. 5. 6. RESPIROLOGY 15/04/19 Emerging respiratory infections threatening public health in the Asia‐Pacific region: A position paper of the Asian Pacific Society of Respirology.
Emerging infectious diseases such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), pandemic influenza A(H1N1) 2009 (influenza A(H1N1)pdm09) and avian influenza (AI) pose a threat to global health. Bird and swine influenza viruses continuously obtain new gene segments through reassortment with human strains. Moreover, infections by multidrug‐resistant Gram‐negative bacteria are also increasing worldwide. Hence, action is needed to curtail the dissemination of these organisms. For this position paper, members of the Asian Pacific Society of Respirology (APSR) Respiratory Infections Assembly selected respiratory pathogens that are most likely to pose significant threats to humans, particularly in the Asia‐Pacific region. The members reviewed epidemiological features of the pathogens and put together a consensus opinion.
Summary and Recommendations A(H7N9) virus A human case of A(H7N9) infection was first reported in March 2013 in China. A(H5N1) virus CoV. THE JOURNAL OF TRANSLATIONAL IMMUNOLOGY 16/04/19 Vaccines for emerging pathogens: from research to the clinic. Historically, vaccines have had enormous impact on human health, eradicating smallpox, polio and many other childhood and adult infections of public health concern. Worldwide, attention is now turning to the task of vaccines for these emerging and re‐emerging pathogens, with renewed interest and support from international governments, the World Health Organization (WHO) and organizations such as the Coalition for Epidemic Preparedness Innovations (CEPI), the Global Alliance for Vaccines and Immunization (GAVI) and philanthropic organizations such as the Gates Foundation.
This review series sets out to survey the progress to date. In their article, Afrough, Dowall and Hewson 1 review a range of emerging viruses and make the case for applying molecular techniques to understand viral pathogenesis. Understanding the interaction of the host with a viral pathogen to expedite vaccine development is a theme taken up in the review contributed by Sharpe et al. 2. CLINICAL & EXPERIMENTAL IMMUNOLOGY 16/04/19 Emerging viruses and current strategies for vaccine intervention. Tiho-hannover_de - 2018 - Thèse en ligne : Emerging and Re-emerging Viruses in Animals : Evolutionary Inferences and Molecular Characterization. NATURE 05/10/18 Generation of therapeutic antisera for emerging viral infections. Cells and viruses Vero E6 cells (ATCC CRL-1586), MDCK cells (ATCC CCL-34) and HEK-293 cells (ATCC CRL-1573) were maintained at 37 °C and 5% CO2 in Dulbecco’s modified Eagle’s medium (DMEM, Sigma-Aldrich) supplemented with 5% (v/v) fetal bovine serum (FBS, Invitrogen) and 200 mM l-glutamine (Sigma-Aldrich).
The recombinant vesicular stomatitis expressing the GP derived from Zaire EBOV isolate Kikwit in place of the original VSV GP (VSVΔG/EBOV-GP)34 as well as the Zaire EBOV strains Makona and Mayinga, and the NiV strain Malaysia were grown on Vero E6 cells. The viral titers of the Zaire EBOV and NiV strains were determined by limited dilution, using cytopathic effect (CPE) as read out. VSVΔG/EBOV-GP was concentrated by centrifugation for 1 h at 100,000 × g and 4 °C through a 20% (w/v) sucrose cushion and resuspended in DMEM or in phosphate-buffered saline (PBS) for immunizations.
Viral titers were determined by plaque assay using Avicel RC-591 overlay (FMC Corporation). BioMed Research International Volume 2014, Epidemiology, Phylogeny, and Evolution of Emerging Enteric Picobirnaviruses of Animal Origin and Their Relationship to Human Strains. Int. J. Mol. Sci. 2018, 19(2), Molecular Research on Emerging Viruses: Evolution, Diagnostics, Pathogenesis, and Therapeutics. BIOXIV 20/02/18 Whole-genome sequencing of parvoviruses from wild and domestic animals in Brazil provides new insights into parvovirus distribution and diversity.
UNIVERSITAT AUTONOMA DE BARCELONA - 2013 - Poster : Emerging viruses of the United States. Pesq. Vet. Bras. vol.33 no.10 Rio de Janeiro Oct. 2013 Emerging animal viruses: real threats or simple bystanders? Emerging animal viruses: real threats or simple bystanders? Vírus emergentes de animais: verdadeiras ameaças ou meros espectadores? Eduardo Furtado FloresI,*; Rudi WeiblenI; Juliana Felipetto CargneluttiI; Fernando Viçosa BauermannII; Fernando Rosado SpilkiIII; Enio MoriIV; Ana Cláudia FrancoV ISetor de Virologia, Departamento de Medicina Veterinária Preventiva (DMVP), Centro de Ciências Rurais, Universidade Federal de Santa Maria (UFSM), Av. Roraima 1000, Camobi, Santa Maria, RS 97105-900, Brazil IIRuminant Diseases and Immunology Research Unit, National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture (USDA), Ames, IA, USA IIILaboratório de Microbiologia Molecular, Instituto de Ciências da Saúde, Universidade Feevale, Novo Hamburgo, RS 93352-000, Brazil IVInstituto Pasteur, Av.
The list of animal viruses has been frequently added of new members raising permanent concerns to virologists and veterinarians. Canine influenza virus (CIV) UNIVERSITAT AUTONOMA DE BARCELONA - 2013 - Poster : Emerging and Re-‐emerging Viruses & Climate Change. OFPP (CH) via ARAMIS - Programme de recherche 2011-2013 - Monitoring of new and re-emerging viruses in Switzerland. FORMATEX - 2013 - Emerging and re-emerging viral diseases: risks and controls. PLOS 01/05/14 PARV4: An Emerging Tetraparvovirus. Citation: Matthews PC, Malik A, Simmons R, Sharp C, Simmonds P, Klenerman P (2014) PARV4: An Emerging Tetraparvovirus.
PLoS Pathog 10(5): e1004036. Editor: Richard C. Condit, University of Florida, United States of America Published: May 1, 2014 Copyright: © 2014 Matthews et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: PCM is an NIHR research fellow and has received funding from the Oxford University Clinical Academic Graduate School. Competing interests: The authors have declared that no competing interests exist. What Is PARV4? PARV4 was first reported in 2005 in a hepatitis B virus–infected injecting drug user (IDU) . Figure 1. What Is the Origin of PARV4 in Humans? References. PLOS 25/06/14 The Microbial Detection Array for Detection of Emerging Viruses in Clinical Samples - A Useful Panmicrobial Diagnostic Tool.
ANNUAL REV VIROL - 2014 - forty years with emerging viruses. Vincent Racaniello VIA YOUTUBE 20/04/17 Virology Lectures 2017 #22: Emerging Viruses. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 30/12/16 Evolutionary ecology of virus emergence. NPR 07/02/17 MAP: Find Out What New Viruses Are Emerging In Your Backyard. JOURNAL OF TROPICAL DISEASES - 2015 - Some New Emerging Viral Diseases in South America and East Africa: The Four Viruses, Itaya, Iquitos, Ngari and Ilesha Virus.
VIROLOGICA SINICA - 2016 - Virus like particle-based vaccines against emerging infectious disease viruses. UNIVERSITY OF TENNESSEE - DEC 2014 - Thèse en ligne : Control of emerging foodborne viruses using cranberry extracts and chemical sanitizers. NATIONAL ACADEMIES - MARS 2015 - Emerging Viral Diseases: The One Health Connection: Workshop Summary (2015) Current Opinion in Virology Volume 3, Issue 2, April 2013, Animal models for highly pathogenic emerging viruses. Ann. Ist. Super. Sanità vol.48 n.4 Roma Oct./Dec. 2012 Emerging and potentially emerging viruses in water environments. SCIENCE MAG 06/12/13 From persistence to cross-species emergence of a viral zoonosis. ECOHEALTH 03/09/13 New Research Identifies a Possible Finite Number of New Viruses. Journal of Molecular Biochemistry (2013) 2, 80-84 An update on virology and emerging viral epidemics. Viruses 2012, 4, 236-257 Emerging Viruses in the Felidae: Shifting Paradigms. EMERGING MICROBES & INFECTIONS 26/12/12 Emerging virus diseases: can we ever expect the unexpected?
MBIO 14/06/11 An insect Nidovirus emerging from a primary tropical rainforest. ERCIYESTIPDERGISI - 2010 - Determinants Contributing to the Newly Emergent Viruses. CDC EID - MARS 2011 - Amplification of Emerging Viruses in a Bat Colony. CDC EID - DEC 2007 - Emerging Viruses in Human Populations. CLINICAL MICROBIOLOGY REVIEWS, July 2006, p. 531–545 Bats: Important Reservoir Hosts of Emerging Viruses. UNIVERSITE D OAKLAND - Présentation : EMERGING VIRUSES. UNIVERSITY OF NEW MEXICO - Présentation : PREDICTIVE UNDERSTANDING OF HUMAN RISK TO EMERGING VIRUSES. J. Biosci. 33(4), November 2008, 617–628, Rapid and real-time detection technologies for emerging viruses of biomedical importan.
Interdisciplinary Perspectives on Infectious Diseases Volume 2009 (2009), Effects of Climate Change on Ticks and Tick-Borne Dise. Health Sciences: An Open Access Peer Reviewed E-Journal. 2012 PRIORITIES AND FUTURE OF DIAGNOSIS OF EMERGING VIRAL DISEASES.