PLOS 19/05/17 Measuring changes in transmission of neglected tropical diseases, malaria, and enteric pathogens from quantitative antibody levels. Abstract Background Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance.
Most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. Analysis methods have predominantly maintained a single disease focus, yet integrated surveillance platforms would benefit from methodologies that work across diverse pathogens included in multiplex assays. Methods/Principal findings We developed an approach to measure changes in transmission from quantitative antibody levels that can be applied to diverse pathogens of global importance. Conclusions/Significance Author summary Editor: Mathieu Picardeau, Institut Pasteur, FRANCE Introduction.
PLOS 23/02/17 Global urbanization and the neglected tropical diseases. Citation: Hotez PJ (2017) Global urbanization and the neglected tropical diseases.
PLoS Negl Trop Dis 11(2): e0005308. doi:10.1371/journal.pntd.0005308 Editor: Peter Steinmann, Swiss Tropical and Public Health Institute, SWITZERLAND Published: February 23, 2017 Copyright: © 2017 Peter J. Hotez. Funding: The author received no specific funding for this work. PLOS 20/04/17 How to determine if a model is right for neglected tropical disease decision making. Abstract Mathematical and computational modeling can transform decision making for neglected tropical diseases (NTDs) if the right model is used for the right question.
Modeling can help better understand and address the complex systems involved in making decisions for NTD prevention and control. However, all models, modelers, and modeling are not the same. Thus, decision makers need to better understand if a particular model actually fits their needs. Here are a series of questions that a decision maker can ask when determining whether a model is right for him or her. Citation: Lee BY, Bartsch SM (2017) How to determine if a model is right for neglected tropical disease decision making. Editor: Serap Aksoy, Yale School of Public Health, UNITED STATES. TRENDS IN PARASITOLOGY - OCT 2007 - Neglected tropical diseases in Uganda: the prospect and challenge of integrated control. Acta Tropica Volume 165, January 2017, Microbiological laboratory diagnostics of neglected zoonotic diseases (NZDs)
Volume 165, January 2017, Pages 40–65.
PLOS 15/09/16 The Role of Nurses and Community Health Workers in Confronting Neglected Tropical Diseases in Sub-Saharan Africa: A Systematic Review. Abstract Introduction Neglected tropical diseases produce an enormous burden on many of the poorest and most disenfranchised populations in sub-Saharan Africa.
Similar to other developing areas throughout the world, this region’s dearth of skilled health providers renders Western-style primary care efforts to address such diseases unrealistic. Consequently, many countries rely on their corps of nurses and community health workers to engage with underserved and hard-to-reach populations in order provide interventions against these maladies. Parasite Epidemiology and Control Volume 1, Issue 2, (June 2016) Trends and spatial patterns of mortality related to neglected tropical diseases in Brazil.
Abstract We analysed nationwide trends and spatial distribution of NTD-related mortality in Brazil.
We included all death certificates in Brazil from 2000 to 2011, in which NTDs were recorded as any causes of death. A total of 100,814/12,491,280 (0.81%) death certificates were identified, which mentioned at least one NTD. Age-adjusted NTD-related mortality rates showed a significant decrease over time (annual percent change [APC]: − 2.1%; 95% CI: − 2.8 to − 1.3), with decreasing mortality rates in the Southeast, South, and Central-West regions, stability in the Northeast region, and increase in the North region.
We identified spatial and spatiotemporal high-risk clusters for NTD-related mortality in all regions, with a major cluster covering a wide geographic range in central Brazil. Keywords. Evol Appl. 2016 Feb; 9(2): 313–333. One health – an ecological and evolutionary framework for tackling Neglected Zoonotic Diseases. PATH 11/04/16 Fighting disease, fear, and fatigue - Game-changing new tools address two of the nastiest neglected tropical diseases. Parasite Epidemiology and Control Volume 1, Issue 2, June 2016, Trends and spatial patterns of mortality related to neglected tropical diseases in Brazil. DEFRA 17/03/16 Contingency plan for exotic notifiable diseases of animals 2016.
PARLEMENT EUROPEEN - Réponse à question E-000836-16 Combating the growing incidence of tropical diseases in Europe. LIVERPOOL SCHOOL OF TROPICAL MEDICINE - Centre for Neglected Tropical Diseases. Bol Med Hosp Infant Mex 2011;68(2):86-90 The global burden of neglected tropical diseases. Artículo The global burden of neglected tropical diseases Jessica S.
Herrera,1 Carlos Franco–Paredes,2 and José Ignacio Santos–Preciado3 1 University of Washington School of Medicine, Seattle, Washington, USA 2 Hospital Infantil de México Federico Gómez, México, D.F., México; Rollins School of Public Health, Emory University, Atlanta, Georgia, USA 3 Unidad de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, México, D.F., México Correspondence: Carlos Franco Paredes, MD, PhD Rollins School of Public Health, Emory University Atlanta, Georgia E–mail: email@example.com. BMJ 21/07/14 US incentive scheme for neglected diseases: a good idea gone wrong? The US priority review voucher scheme was intended to encourage drug companies to invest in treatments for neglected diseases.
But nearly seven years on, as Peter Doshi reports, there is little demonstrated innovation and evidence that the benefits are not going where they were intended Bill Gates believes—or at least believed—that government led market incentives could solve the fundamental conundrum in developing drugs for neglected diseases. For-profit companies see little economic justification to invest in treating diseases that affect the poor, but “creative capitalism,” as Gates put it, could lure companies into solving some of the world’s most pressing problems by bringing to market new treatments for endemic tropical diseases.
Gates was not the only one to be excited about the idea. But more than six years later, has this promising concept flopped? THE LANCET - OCT 2014 - Neglected tropical diseases: no longer someone else's problem. Neglected tropical diseases were once thought to be restricted to developing countries, largely because climate and inadequate health infrastructures allow the organisms and their vectors to thrive.
However, at the beginning of September, Japan reported its first outbreak of dengue since 1945. And over the past year, autochthonous chikungunya has been spreading through the Caribbean reaching mainland USA in July. These worrying developments show that it might be time to reassess the old ideas about the distribution of these diseases. The incursion of chikungunya into the USA might have been thought an unfortunate but isolated development were it not for the host of other neglected tropical diseases, including dengue, now endemic in the country. MURDOCH UNIVERSITY - 2013 - Epidemiology of zoonotic and neglected tropical diseases in the Lao People’s Democratic Republic. Conlan, James (2013) Epidemiology of zoonotic and neglected tropical diseases in the Lao People’s Democratic Republic.
PhD thesis, Murdoch University. Laos is one of the poorest and least developed countries in Southeast Asia and living conditions, livestock production and cultural practices place large proportions of the population at risk of exposure to a range of parasitic and viral zoonoses. OMS - FEV 2015 - Investing to overcome the global impact of neglected tropical diseases - Third WHO report on neglected tropical diseases.
BMC 11/06/15 Challenges and opportunities associated with neglected tropical disease and water, sanitation and hygiene intersectoral integration programs. All 24 interviews explored possible barriers or challenges to intersectoral collaboration of NTD and WASH programs. Participants also identified and discussed several needs or ideal conditions for future integration efforts.
Both the barriers and the ideal conditions discussed in this section were the most commonly stated themes among interview participants, regardless of sector of work or type of organization. The principal barriers and ideal conditions are characterized below. Barriers The interview participants revealed several important insights regarding the barriers that their organizations face when trying to implement NTD and WASH integration programs. Table 5. Differing programmatic objectives Differing programmatic objectives was the barrier most commonly mentioned by interview participants. Participant 23: That is a challenge, the WASH organizations have their own objectives, they have their own donor goals. LIVERPOOL SCHOOL OF TROPICAL MEDICINE 01/06/15 The best buy in global public health One of the world's top experts on tropical disease explains why action on poverty-related illnesses is a must – and simpler than we might think. David Molyneux is Director of the Lymphatic Filariasis Support Centre at the Liverpool School of Tropical Medicine since 2000.
He is also Executive Secretary of the Executive Group of the Global Alliance to Eliminate Lymphatic Filariasis. Professor Molyneux was Director of the Liverpool School of Tropical Medicine from 1991 to 2000, and is currently Professor of Tropical Health Sciences at the University of Liverpool. Some are transmitted by mosquitoes, some are caused by worms and as a diverse group micro-organisms; others by snakebites. They affect the lives and the economic prospects of roughly every fourth person on the planet – usually the poorest. PARLEMENT EUROPEEN - Réponse à question E-002248-15 Neglected tropical diseases. BLOG BIOMED 30/03/15 News of Neglected Tropical Diseases. Participants at the ISNTD Bites meeting, 2015 What are neglected tropical diseases (NTDs)? Mathew Baylis gives his definition at the annual ISNTD Bites meeting held in London this month.
“I see it as meaning a disease that is understudied relative to its impact”. DEFRA 11/03/15 United Kingdom contingency plan for exotic notifiable diseases of animals (màj) OMS via YOUTUBE – FEV 2015 – Emission vidéo d'1H30 consacrée au même sujet. OMS - FEV 2015 - Investing to overcome the global impact of neglected tropical diseases - Third WHO report on neglected tropical diseases. CDC 10/07/14 Neglected Parasitic Infections (NPIs) in the United States. Parasitic infections are typically associated with poor and often marginalized communities in low-income countries. However, these infections are also present in the United States.
The neglected parasitic infections (NPIs) are a group of five parasitic diseases that have been targeted by the CDC as priorities for public health action based on the. Strengthening Neglected Tropical Disease Research through Enhancing Research-Site Capacity: An Evaluation of a Novel Web Application to Facilitate Research Collaborations. Figures Citation: Furtado T, Franzen S, van Loggerenberg F, Carn G, Grahek S, et al. (2014) Strengthening Neglected Tropical Disease Research through Enhancing Research-Site Capacity: An Evaluation of a Novel Web Application to Facilitate Research Collaborations. PLoS Negl Trop Dis 8(11): e3225. doi:10.1371/journal.pntd.0003225 Editor: Alejandro Javier Krolewiecki, Instituto de Investigaciones en Enfrmedades Tropicales. Universidad Nacional de Salta, Argentina Published: November 13, 2014 Copyright: © 2014 Furtado et al. Funding: This report is based on research funded in part by the Bill & Melinda Gates Foundation. Competing interests: The authors have declared that no competing interests exist.
ADVANZ - Advocacy for neglected zoonotic diseases. INFECTION ECOLOGY & EPIDEMIOLOGY - 2012 - Threats from emerging and re-emerging neglected tropical diseases (NTDs) INTERDISCIPLINARY PERSPECTIVES ON INFECTIOUS DISEASES - 2012 - Neglected Infectious Diseases: Mechanism of Pathogenesis, Diagnos. Swiss Med Wkly. 2012;142:w13727 Neglected tropical diseases: diagnosis, clinical management, treatment and control. FDA - AOUT 2011 - DRAFT Guidance for Industry Neglected Tropical Diseases of the Developing World: Developing Drugs for Treatmen. 2010 - CDC’s Neglected Tropical Diseases Program. Louisiana State University - 2011 - Dissertation en ligne : MAPPING AND MODELING OF NEGLECTED TROPICAL DISEASES IN BRAZIL AND BO.
A Peer-Reviewed Open-Access Journal. BBSRC - 2014 - Zoonoses and Emerging Livestock Systems (ZELS) Reducing the risk to livestock and people Research Programme 2014.