EUROSURVEILLANCE 03/11/16 Weighing serological evidence of human exposure to animal influenza viruses − a literature review. ZOONOSES AND PUBLIC HEALTH - 2009 - The Role of Swine in the Generation of Novel Influenza Viruses. Journal of Swine Health and Production - 2005 - Defining swine influenza virus. BLOG ZOONOTICECOLOGY 16/06/16 Influenza A virus epidemiology – from individual disease histories to disease dynamics. Wildlife disease studies are challenging.
That’s a fact. If you want an easy science life you should choose another path with more instant results. However, challenging is also the opposite of boring, and the rewards of getting your results are even more exhilarating when lots of toil, sweat and tears have been invested. As readers of this blog are aware, wildlife disease studies are what we do, and I have repeatedly written about our ongoing work on influenza A virus ecology and epidemiology in wild migratory Mallards. This week another study from our study site was published, entitled Capturing individual-level parameters of influenza A virus dynamics in wild ducks using multistate models, which can be found on early view in the Journal of Applied Ecology.
We, however, sit on a huge collection of Mallard and flu data gathered at the same study site with similar methods over a period of close to 15 years. The conceptual framework in the multistate CMR model. Link to the paper: Like this: One Health Volume 1, December 2015, One health, multiple challenges: The inter-species transmission of influenza A virus. Abstract Influenza A viruses are amongst the most challenging viruses that threaten both human and animal health.
Influenza A viruses are unique in many ways. Firstly, they are unique in the diversity of host species that they infect. This includes waterfowl (the original reservoir), terrestrial and aquatic poultry, swine, humans, horses, dog, cats, whales, seals and several other mammalian species. Secondly, they are unique in their capacity to evolve and adapt, following crossing the species barrier, in order to replicate and spread to other individuals within the new species. Introduction. PLOS 11/02/16 Airborne Influenza A Is Detected in the Personal Breathing Zone of Swine Veterinarians. Abstract The 2009 H1N1 pandemic emphasized a need to evaluate zoonotic transmission of influenza A in swine production.
Airborne influenza A virus has been detected in swine facilities during an outbreak. However, the personal exposure of veterinarians treating infected swine has not been characterized. Two personal bioaerosol samplers, the NIOSH bioaerosol sampler and the personal high-flow inhalable sampler head (PHISH), were placed in the breathing zone of veterinarians treating swine infected with either H1N1 or H3N2 influenza A. A greater number of viral particles were recovered from the NIOSH bioaerosol sampler (2094 RNA copies/m3) compared to the PHISH sampler (545 RNA copies/m3). INFECTION ECOLOGY & EPIDEMIOLOGY - 2011 - Influenza A viruses: an ecology review. John Wahlgren PhD* Department for Preparedness, Swedish Institute for Infectious Disease Control, Solna, Sweden Abstract In humans, influenza A viruses cause yearly outbreaks with high morbidity and excess fatality rates as a direct effect.
Placed in its ecological niche, however – in dabbling ducks – avian influenza virus (AIV) induces quite a mild disease. It is when the virus crosses the species barrier that pathogenic traits are attributed to infection. VIROLOGY BLOG 20/06/14 Reconstruction of 1918-like avian influenza virus stirs concern over gain of function experiments. The gain of function experiments in which avian influenza H5N1 virus was provided the ability to transmit by aerosol among ferrets were met with substantial outrage from both the press and even some scientists; scenarios of lethal viruses escaping from the laboratory and killing millions proliferated (see examples here and here).
The recent publication of new influenza virus gain of function studies from the laboratories of Kawaoka and Perez have unleashed another barrage of criticism. What exactly was done and what does it mean? BIOMEDICAL JOURNAL 10/02/14 Avian influenza A virus infection in humans. Avian influenza A virus infection in humans Guang-Wu Chen1, Shin-Ru Shih2 1 Research Center for Emerging Viral Infections, College of Medicine; Department of Computer Science and Information Engineering, School of Electrical and Computer Engineering, College of Engineering, Chang Gung University, Taoyuan, Taiwan2 Research Center for Emerging Viral Infections; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan; Clinical Virology Laboratory, Department of Clinical Pathology, Chang Gung Memorial Hospital at Linkou, Taiwan Correspondence Address:Shin-Ru ShihResearch Center for Emerging Viral Infections, College of Medicine, Chang Gung University. 259 Wenhua 1st Rd., Gueishan, Taoyuan 333 Taiwan.
EFSA 22/05/14 Interview with Ron Fouchier: transmission of influenza viruses from animals to humans. Ron Fouchier Flu researcher from the Erasmus Medical Centre in the Netherlands Can influenza strains jump from animals to humans?
R.F.: Yes. Several strains circulating in poultry or pigs have infected humans (e.g. from subtypes H1N1, H3N2, H5N1, H6N1 H7N7, H7N9, H10N7). Luckily, this generally results in single human cases of infection, with no sustained transmission between humans. Why is this a concern? R.F.: Of course every human infection is one too many, especially if they lead to severe diseases or fatalities. Does this happen often? EFSA 22/05/14 Influenza viruses: EFSA looks at transmission from animals to humans. MBIO - MARS 2014 - Characterization of a Novel Influenza Virus in Cattle and Swine: Proposal for a New Genus in the Orthomyxoviridae Family. + Author Affiliations Address correspondence to Feng Li, firstname.lastname@example.org.
Editor Peter Palese, Icahn School of Medicine at Mount Sinai We have recently reported the isolation of a novel virus, provisionally designated C/swine/Oklahoma/1334/2011 (C/OK), with 50% overall homology to human influenza C viruses (ICV), from a pig in Oklahoma. Deep RNA sequencing of C/OK virus found a matrix 1 (M1) protein expression strategy that differed from that of ICV. INFECTION ECOLOGY & EPIDEMIOLOGY - 2011 - Influenza A viruses: an ecology review. JOURNAL OF VETERINARY RESEARCH - 2012 - Zoonotic diseases and human health: The human influenza example.
TOPLEY WILSON - Dossier de 65 pages : Orthomyxoviruses: influenza. A comprehensive reference to microorganisms and the resulting infectious diseases currently available.
Forming a unique online resource that provides a handy reference for medical microbiologists, immunologists, infectious disease specialists, pathologists and public health scientists. Provides extensive coverage of virology, bacteriology, medical mycology, parasitology and immunology. It includes the latest information on epidemiology, identification, classification and new and emerging infections, all supported by the basic science that underlie infectious disease. The content is topical with the current world issues on viral epidemics and biological warfare threats. Content is supported by over 1,400 full color photographs and 700 line drawings.
FAO-OIE-WHO Joint Technical Consultation - Verona, Italy, 7-9 October 2008. ESNIP 2 - The European surveillance Network for Influenza in Pigs. FLU LAB NET (le site semble uniquement accessible via identification) Site officiel : Influenza Report 2006 is a medical textbook that provides a comprehensive overview of epidemic and pandemic influenza. Access to.
PLOS OCT 2007 Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature. Abstract Using the guinea pig as a model host, we show that aerosol spread of influenza virus is dependent upon both ambient relative humidity and temperature.
Twenty experiments performed at relative humidities from 20% to 80% and 5 °C, 20 °C, or 30 °C indicated that both cold and dry conditions favor transmission. The relationship between transmission via aerosols and relative humidity at 20 °C is similar to that previously reported for the stability of influenza viruses (except at high relative humidity, 80%), implying that the effects of humidity act largely at the level of the virus particle.
For infected guinea pigs housed at 5 °C, the duration of peak shedding was approximately 40 h longer than that of animals housed at 20 °C; this increased shedding likely accounts for the enhanced transmission seen at 5 °C. To investigate the mechanism permitting prolonged viral growth, expression levels in the upper respiratory tract of several innate immune mediators were determined. Figures. AED - Avian and Pandemic Influenzas Resource Link. Rev Biomed 2006; 17:69-79. 1918 Influenza: The mother of all pandemics. Avian Influenza: The Virus & Its Spread. Rev Biomed 2006; 17:69-79. 1918 Influenza: The mother of all pandemics. Rev Biomed 1999; 10:57-61. Influenza: the history of a disease. Table of Contents — January 2010, 47 (1) VETERINARY PATHOLOGY JANV 2010 Emerging and Reemerging Influenza Virus Infections.
NATIONAL ACADEMIES - 2005 -,The Threat of Pandemic Influenza. USDA - Agriculture Research Service - Présentation : The Origins and Host Specificity of Type A Influenza Virus.