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NATURE 15/01/20 Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment. Characteristics of the surveillance Plague-surveillance work in the Guertu region began in 1964.

Résumé traduit : Nos résultats soutiennent la notion que la bactérie s'adapte constamment - grâce à des changements étendus de phénotype dans les puces - en réponse aux changements climatiques de la niche. – guatemalt

Routine surveillance, including the type and distribution of host/vector, host animal density, flea index, and bacteria isolation was performed each year, and the first Y. pestis strain in Guertu was isolated in 1967.

NATURE 15/01/20 Evolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment.

The sentinel site in Guertu was established in 1983. Plague-surveillance staff lived and worked at the sentinel site from May to October each year, when Spermophilus undulatus and Marmota baibacina, the hosts of Y. pestis, emerge from hibernation. Once the sentinel site was established, seropositivity rate was also measured. Biosafety and Health Volume 1, Issue 2, September 2019, Yersinia pestis, a problem of the past and a re-emerging threat. R.C.

Résumé traduit : Cet article discute de la menace de Yersinia pestis dans le monde moderne en considérant sa prévalence et la gravité des maladies qu'il provoque, sa transmission, sa résistance aux antibiotiques et son potentiel comme arme biologique. – guatemalt

Ngeleja, L.S.

Biosafety and Health Volume 1, Issue 2, September 2019, Yersinia pestis, a problem of the past and a re-emerging threat.

Luboobi, Y. Nkansah-GyekyeThe effect of seasonal weather variation on the dynamics of the plague disease M. PARASITES & VECTORS 06/11/19 First detection of the kdr mutation (L1014F) in the plague vector Xenopsylla cheopis (Siphonaptera: Pulicidae) Detection of kdr mutations Sequencing of each amplicon resulted in a clear 369-bp sequence, encompassing two full short introns, a full exon and two partial exons (Fig. 1).

PARASITES & VECTORS 06/11/19 First detection of the kdr mutation (L1014F) in the plague vector Xenopsylla cheopis (Siphonaptera: Pulicidae)

Eight nucleotide polymorphisms in the 369-bp fragments were observed from a total of 111 individuals. No nucleotide variation was observed in the first and last partial exons. One non-synonymous mutation, leading to a deduced amino acid substitution of L (CTT) to F (TTT) at the position corresponding to the amino acid residue 1014 of VGSC of the housefly was detected in the second exon, while other three nucleotide polymorphisms in this exon were synonymous. Four polymorphic sites were found in the two introns in total, without length polymorphism being observed (Fig. 1). Schematic representation of the region of Xenopsylla cheopis VGSC gene analyzed in this study. SPRINGER 09/10/16 Bacteriophages of Yersinia pestis. Rev. Soc. Bras. Med. Trop. vol.50 no.6 Uberaba Nov./Dec. 2017 Seroprevalence and spatial distribution dynamics of Yersinia pestis antibodies in dogs and cats from plague foci in the State of Ceará, Northeastern Brazil.

PLOS - OCT 2012 - Dynamics of Yersinia pestis and Its Antibody Response in Great Gerbils (Rhombomys opimus) by Subcutaneous Infection. Abstract Background.

PLOS - OCT 2012 - Dynamics of Yersinia pestis and Its Antibody Response in Great Gerbils (Rhombomys opimus) by Subcutaneous Infection

Braz. J. Microbiol. vol.49 no.1 São Paulo Jan./Mar. 2018 Yersinia pestis detection by loop-mediated isothermal amplification combined with magnetic bead capture of DNA. References.

Braz. J. Microbiol. vol.49 no.1 São Paulo Jan./Mar. 2018 Yersinia pestis detection by loop-mediated isothermal amplification combined with magnetic bead capture of DNA

PLOS 16/08/18 Human plague associated with Tibetan sheep originates in marmots. Abstract The Qinghai-Tibet plateau is a natural plague focus and is the largest such focus in China.

PLOS 16/08/18 Human plague associated with Tibetan sheep originates in marmots

In this area, while Marmota himalayana is the primary host, a total of 18 human plague outbreaks associated with Tibetan sheep (78 cases with 47 deaths) have been reported on the Qinghai-Tibet plateau since 1956. All of the index infectious cases had an exposure history of slaughtering or skinning diseased or dead Tibetan sheep. CDC EID - FEV 2018 - Yersinia pestis Survival and Replication in Potential Ameba Reservoir. Author affiliations: Colorado State University, Fort Collins, Colorado, USA (D.W.

CDC EID - FEV 2018 - Yersinia pestis Survival and Replication in Potential Ameba Reservoir

Markman, M.F. Antolin, R.A. Bowen, W.H. CDC EID - FEV 2018 - Ecologic Features of Plague Outbreak Areas, Democratic Republic of the Congo, 2004–2014. Aaron Aruna Abedi ( , Jean-Christophe Shako, Jean Gaudart, Bertrand Sudre, Benoit Kebela Ilunga, Stomy Karhemere Bi Shamamba, Georges Diatta, Bernard Davoust, Jean-Jacques Muyembe Tamfum, Renaud Piarroux, and Martine Piarroux Author affiliations: Ministry of Health, Kinshasa, Democratic Republic of the Congo (A.A.

CDC EID - FEV 2018 - Ecologic Features of Plague Outbreak Areas, Democratic Republic of the Congo, 2004–2014

Abedi, B.K. CDC EID - JANV 2018 - Dangers of Noncritical Use of Historical Plague Data. Author affiliations: Utrecht University, Utrecht, the Netherlands (J.

CDC EID - JANV 2018 - Dangers of Noncritical Use of Historical Plague Data

Roosen); Leiden University, Leiden, the Netherlands (D.R. Recording Archaeology VIA YOUTUBE 30/01/17 From Mild to Murderous: How Yersinia pestis Evolved to Cause Pneumonic Plague. ONTARIO VETERINARY COLLEGE via CLINICIANSBRIEF - AVRIL 2017 - Plague in Domestic Cats. ECDC - SEPT 2016 - Annual epidemiological report - Plague. No cases of plague were reported in EU/EEA countries in 2014. ASTMH - SEPT 2017 - Identification of Risk Factors Associated with Transmission of Plague Disease in Eastern Zambia.

ASTMH - SEPT 2016 - Reannotation of Yersinia pestis Strain 91001 Based on Omics Data. Adv Exp Med Biol. 09/10/16 Pathology and Pathogenesis of Yersinia pestis. BUSINESSINSIDER 14/08/17 Fleas carrying the bubonic plague have been found in Arizona. CDC 14/09/15 Frequently Asked Questions. What is plague?

CDC 14/09/15 Frequently Asked Questions

Plague is an infectious disease that affects rodents, certain other animals, and humans. It is caused by the Yersinia pestis bacteria. These bacteria are found in many areas of the world, including the United States. How do people become infected with plague? People most commonly acquire plague when they are bitten by a flea that is infected with the plague bacteria. CLINICAL MICROBIOLOGY REVIEWS, Apr. 2004, p. 434–464 Intraspecific Diversity of Yersinia pestis. + Author Affiliations Increased interest in the pathogenic potential of Yersinia pestis has emerged because of the potential threats from bioterrorism. Pathogenic potential is based on genetic factors present in a population of microbes, yet most studies evaluating the role of specific genes in virulence have used a limited number of strains.

For Y. pestis this issue is complicated by the fact that most strains available for study in the Americas are clonally derived and thus genetically restricted, emanating from a strain of Y. pestis introduced into the United States in 1902 via marine shipping and subsequent spread of this strain throughout North and South America. In countries from the former Soviet Union (FSU), Mongolia, and China there are large areas of enzootic foci of Y. pestis infection containing genetically diverse strains that have been intensely studied by scientists in these countries. ↵*Corresponding author. American Society for Microbiology. CDC EID - Volume 23, Number 9—September 2017. Au sommaire notamment: Patterns of Human Plague in Uganda, 2008–2016. Joseph D. Forrester, Titus Apangu, Kevin Griffith, Sarah Acayo, Brook Yockey, John Kaggwa, Kiersten J. Kugeler, Martin Schriefer, Christopher Sexton, C. Ben Beard, Gordian Candini, Janet Abaru, Bosco Candia, Jimmy Felix Okoth, Harriet Apio, Lawrence Nolex, Geoffrey Ezama, Robert Okello, Linda Atiku, Joseph Mpanga, and Paul S.

Mead. TRANSBOUNDARY AND EMERGING DISEASES 24/01/17 Wildlife Plague Surveillance Near the China–Kazakhstan Border: 2012–2015. IDAHO DEPARTMENT OF HEALTH & WELFARE - 2015 - FREQUENTLY ASKED QUESTIONS ABOUT PLAGUE. CELL - OCT 2015 - Early Divergent Strains of Yersinia pestis in Eurasia 5,000 Years Ago. INDEPENDENT 15/07/16 Russian boy catches the bubonic plague while hunting in Siberian mountains. A 10-year-old boy caught bubonic plague while hunting with his grandfather in Siberian mountains. The Russian is believed to have caught the potentially deadly disease when he cut himself with a knife while skinning a marmot. Marmots are large rodents which are known to be susceptible to carrying the disease. Marmot hunting is banned in the area due to the risk of catching bubonic plague but the ban is widely ignored.

Bubonic plague caused the Black Death epidemic in the 13th century, killing an estimated 30 per cent of the European population. The unnamed child is in a "serious but stable condition" according to doctors, Mirror reports. CDC EID - Volume 21, Number 2—February 2015 Au sommaire : Murine Typhus, Reunion, France, 2011–2013. Elsa Balleydier1. Journal of microbiological methods. 06/2015; Monitoring biothreat agents (Francisella tularensis, Bacillus anthracis and Yersinia pestis) with a portable real-time PCR instrument. The PikoReal technology presents a strong candidate for further development to support more common public health diagnostic needs, such as respiratory disease-causing agents in primary health care settings. This lightweight and compact system allows rapid and. BELOIT DAILY NEWS 16/09/16 Forget about the Bubonic plague: Professor presents on emerging diseases. BELOIT — Don’t kiss a pig. That message and many other fun knowledge nuggets were part of Beloit College professor Rachel Bergstrom’s presentation on emerging public health threats such as Ebola and Zika.

She spoke at a Society for Learning Unlimited (SLU) presentation at First Congregational Church on Thursday morning. Bergstrom explained how microbial adaptation, human susceptibility to infection and changing ecosystems are some of many growing factors in the outbreak of disease in a time when antibiotic production is not keeping up with demand. CDC EID - JUNE 2008 - Persistence of Yersinia pestis in Soil Under Natural Conditions.

CDC EID - JUILLET 2011 - Yersinia pestis in Small Rodents, Mongolia. Suggested citation for this article To the Editor: Plague is known to be endemic in several areas of Mongolia, but transmission to humans seems to play only a minor role because the number of recognized cases is relatively low (Figure) (1). The first human cases in Mongolia were reported to the World Health Organization in 1980, and <20 human cases have occurred each year since then (2). CDC EID - FEV 2013 - Au sommaire: Yersinia pestis Plasminogen Activator Gene Homolog in Rat Tissues. PLOS 11/02/16 Two Distinct Yersinia pestis Populations Causing Plague among Humans in the West Nile Region of Uganda.

Abstract. PLOS 27/03/14 New Insights into How Yersinia pestis Adapts to Its Mammalian Host during Bubonic Plague. Abstract. RT 29/01/14 Scientists find DNA of first-ever bubonic plague, warn of new outbreaks. Trakia Journal of Sciences - 2014 - YERSINIA PESTIS - OLD AND NEW CHALLENGES IN HUMANS AND IN ANIMALS. ESCIENCECENTRAL 20/06/13 Could the ‘Black Death’ Become a Re-Emerging Infectious Disease? Rev. Soc. Bras. Med. Trop. vol.46 no.4 Uberaba July/Aug. 2013 Seroprevalence of hantavirus and Yersinia pestis antibodies in professionals from the Plague Control Program. Short Communications Seroprevalence of hantavirus and Yersinia pestis antibodies in professionals from the Plague Control Program Érika de Cássia Vieira da Costa[1] [2] , Gerlane Tavares de Souza Chioratto[1] [2] , Paulo Thiago Melo Guaraná[2] [3] , Marise Sobreira[2] , Ivoneida Aragão[4] †, Robervaldo Silva[5] , Sheila Sotelino Rocha[6] , Celso Tavares[7] , Alzira Maria Paiva de Almeida[2]

MMN 22/08/14 Bubonic plague found in Colorado fleas. Colorado health officials have issued a warning to Boulder County residents after bubonic plague was found in fleas taken from a prairie dog. Flea samples were taken from a Boulder property when a homeowner notified officials of several dead prairie dogs on the property. The neighborhood has been posted with signs warning residents to protect themselves and their pets.

The plague has been active in the area every year since 2005, according to Heather Swanson, a wildlife ecologist for Boulder Open Space and Mountain Parks, but this is the first confirmed case in the county since 2011, when a pet cat and a dead squirrel tested positive for it. Journal of Wildlife Diseases, 44(3), 2008, pp. 731-736 Prevalence of Yersinia pestis in Rodents and Fleas Associated with Black-tailed Prairie Dogs (Cynomys ludovicianus) at Thunder Basin National Grassland, Wyoming. PNAS 26/12/12 Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis. Journal of Pathogens Volume 2012 (2012) Rapid Detection and Identification of Yersinia pestis from Food Using Immunomagnetic Sep.

IOWA STATE UNIVERSITY - 2012 - Thèse en ligne : New tools for studying mal gene regulation in Yersinia pestis. Abstract Y. pestis, the etiologic agent of plague, is a significant human pathogen because of its historic role as the cause of three major pandemics and its current role as a potential bioterrorism agent. Gene regulation in this organism is complex and multiple microarray studies have shown that the expression of several genes is affected by quorum sensing as well as temperature. Maltose utilization genes are of particular interest because they are regulated by both of these systems. In order to perform genetic studies on mal genes, and to better understand gene expression in general in Y. pestis, we developed a number of new tools that comprise the majority of the work in this thesis. To take advantage of recombineering as a useful system for constructing new mutants, we improved the protocol to promote a higher efficiency of survival and recombination in electroporated Y. pestis cells.

Recommended Citation. INDIAN ACADEMY OF SCIENCES 25/05/12 Thèse en ligne: The 1994 plague epidemic of India: molecular diagnosis and characterization. PLOS 28/11/12 Yersinia pestis: New Evidence for an Old Infection. The successful reconstruction of an ancient bacterial genome from archaeological material presents an important methodological advancement for infectious disease research.

The reliability of evolutionary histories inferred by the incorporation of ancient data, however, are highly contingent upon the level of genetic diversity represented in modern genomic sequences that are publicly accessible, and the paucity of available complete genomes restricts the level of phylogenetic resolution that can be obtained. Here we add to our original analysis of the Yersinia pestis strain implicated in the Black Death by consolidating our dataset for 18 modern genomes with single nucleotide polymorphism (SNP) data for an additional 289 strains at over 600 positions. Figures. CURRENT SCIENCE, VOL. 88, NO. 5, 10 MARCH 2005 Is Yersinia pestis a distinct species? PLOS 15/09/11 Plague and Climate: Scales Matter. Parasites & Vectors 2011, 4:191 Effects of temperature on the transmission of Yersinia Pestis by the flea, Xenopsylla Cheopis, i. BBC 12/10/11 Black Death genetic code 'built' Nature. 2011 Oct 12;478(7370):506-10. A draft genome of Yersinia pestis from victims of the Black Death.

PNAS 31/01/12 Pulmonary infection by Yersinia pestis rapidly establishes a permissive environment for microbial proliferation. Yersinia pestis. OREGON - Yersinia pestis as a Bioterrorist Agent.