Vaccine Volume 38, Issue 45, 21 October 2020, Safety and efficacy of inactivated African horse sickness (AHS) vaccine formulated with different adjuvants. Theiler A.
African Horse sickness. Science bulletin 1921;19. Erasmus BJ. The pathogenesis of African Horsesickness. Proceedings of the 3rd Int Conf Equine Infectious Diseases. P.G. Onderstepoort J Vet Res, 29 (1962), pp. 139-149 B.M. Onderstepoort J Vet Res, 27 (1958), pp. 465-538 P.A. van RijnAfrican Horse Sickness Virus Reference Module in Life Sciences: Elsevier (2019) N.D. Vet Rec, 172 (2013), p. 152 R.A. Onderstepoort J Vet Science and Animal Industry, 19 (1944), pp. 7-16 G.J. Med Vet Entomol, 14 (2000), pp. 245-250 G.J. Arch. med. vet. vol.47 no.1 Valdivia 2015 Assessment of the risk for introduction of African horse sickness into South American southern cone countries via import of live animals. BMC VETERINARY RESEARCH 01/09/20 Immune response of horses to inactivated African horse sickness vaccines.
Cells Baby hamster kidney 21 (BHK-21) from ATCC, Catalogue No.
CCL-10™ passage number 53 were cultured in Minimum Essential Medium + Earle’s salts + L-Glutamine (MEM, Gibco, USA) supplemented with Fetal bovine serum (FBS, Gibco, Germany) while FBS was omitted for the cell virus replication. Cells were passaged twice per week in T75 flasks at a density of 4.5 × 105 cells/ml and incubated in a humidified incubator at 37 °C with 5.0% CO2. BHK-21 cells were used to generate viral suspensions required to prepare the vaccines which was propagated in T300 flasks. BMC VETERINARY RESEARCH - 2015 - A spatiotemporal model to assess the introduction risk of African horse sickness by import of animals and vectors in France.
Résumé traduit : Les résultats du modèle indiquent que le risque annuel d'introduction de la peste équine en France est très faible mais que des différences spatio-temporelles majeures existent. Pour les deux voies d'introduction, le risque est plus élevé de juillet à octobre et pics en juillet. En général, les régions avec des climats plus chauds sont plus à risque, tout comme les régions plus froides avec une plus grande population d'équidés; cependant, la variation régionale des schémas d'importation d'animaux (nombre et espèces) joue également un rôle majeur pour déterminer le risque. Malgré la faible probabilité de présence d'AHSV dans l'UE, le commerce intra-UE d'équidés contribue plus au risque de l'introduction de l'AHSV en France car elle implique un grand nombre de mouvements de chevaux. – guatemalt
OIE VIA YOUTUBE 14/05/20 6th Webinar on #AfricanHorseSickness: Impact on OIE official status & movement of competition horses. OIE VIA YOUTUBE 29/04/20 4th Webinar on #AfricanHorseSickness for Asia: AHS eradication strategies. OIE 16/04/20 2nd Webinar #AfricanHorseSickness: Diagnostic tests, support from OIE Reference Labs & regional labs. BMC VETERINARY RESEARCH 03/12/19 Plant-produced chimeric virus-like particles - a new generation vaccine against African horse sickness. 1.Coetzer JAW, Guthrie AJ.
African horse sickness. In: Coetzer JAW, Tustin RC, editors. Infectious Diseases of Livestock. 2nd ed. Oxford University Press Southern Africa: Cape Town; 2004. p. 1231–46. Google Scholar2.Mellor PS, Hamblin C. VIRUSES 18/07/19 Evidence of Intragenic Recombination in African Horse Sickness Virus. Intragenic recombination has been described in various RNA viruses as a mechanism to increase genetic diversity, resulting in increased virulence, expanded host range, or adaptability to a changing environment.
Orbiviruses are no exception to this, with intragenic recombination previously detected in the type species, bluetongue virus (BTV). African horse sickness virus (AHSV) is a double-stranded RNA virus belonging to the Oribivirus genus in the family Reoviridae. Genetic recombination through reassortment has been described in AHSV, but not through homologous intragenic recombination. The influence of the latter on the evolution of AHSV was investigated by analyzing the complete genomes of more than 100 viruses to identify evidence of recombination.
ZENODO - 1900 - South African Horse-Sickness: Its Pathology and Methods of Protective Inoculation. VETERINARY RESEARCH 11/10/18 Safety and immunogenicity of plant-produced African horse sickness virus-like particles in horses. African horse sickness (AHS) is a highly infectious, notifiable viral disease which poses a substantial challenge to horse owners in sub-Saharan Africa.
The aetiological agent, African horse sickness virus (AHSV), is an orbivirus of the family Reoviridae, and 9 different serotypes of the virus have been isolated [1, 2]. Immunization with live attenuated vaccines (LAVs)  has been the primary control strategy to date, but recent research has shown that vaccines of this nature carry the inherent risk of reverting to virulence, as well as the possibility of gene segment re-assortment between outbreak and vaccine strains . Moreover, besides the inability to differentiate between natural and vaccine-induced immunity (non-DIVA), the LAV is restricted to use within southern Africa and this has significant implications for both the horse export industry as well as the equestrian sporting arena. The horses were vaccinated according to the schedule described in Table 2. VETERINARY RECORD - 2018 - A possible role for domestic dogs in the spread of African horse sickness virus.
VETERINARIA ITALIANA - 2019 - Evaluating African horse sickness virus in horses and field-caught Culicoides biting midges on the East Rand, Gauteng Province, South Africa. Evaluating African horse sickness virus in horses and field-caught Culicoides biting midges on the East Rand, Gauteng Province, South Africa Anthony F Craig, Glenn C Packer, Alan J Guthrie, Estelle H Venter Abstract.
TRANSBOUNDARY AND EMERGING DISEASES 24/06/19 Establishing post‐outbreak freedom from African horse sickness virus in South Africa's surveillance zone. An African horse sickness (AHS) outbreak occurred in South Africa's AHS controlled area in autumn 2016.
A freedom from disease survey was performed to establish the likelihood of ongoing circulation of the associated virus during the same period the following year. A single‐stage surveillance strategy was employed with a population‐level design prevalence of 1% to establish a survey population sensitivity of 95% (probability that one or more positive horses would be detected if AHS was present at a prevalence greater than or equal to the design prevalence). In March 2017 a total of 262 randomly selected horses from 51 herds were sampled from the 2016 outbreak containment zone. Three within‐herd and herd‐level design prevalence scenarios were used in evaluating the post‐survey probability of freedom. This article is protected by copyright. TRANSBOUNDARY AND EMERGING DISEASES 18/11/18 A field investigation of an African horse sickness outbreak in the controlled area of South Africa in 2016. Transbound Emerg Dis. 2019 Jun 24. Establishing post-outbreak freedom from African horse sickness virus in South Africa's surveillance zone.
SUSTECH_EDU - JANV 2019 - Thèse en ligne : Seroprevalence of African horse sickness in Khartoum state , Sudan. Rhodes University - 2010 - A MODEL OF THE ECONOMIC IMPACT OF AFRICAN HORSE SICKNESS TO THE EQUINE BREEDING INDUSTRY IN SOUTH AFRICA. REVUE D ELEVAGE ET DE MEDECINE VETERINAIRE DES PAYS TROPICAUX - 2018 - Risque épidémiologique de la peste équine africaine chez les ânes au Burkina Faso. Risque épidémiologique de la peste équine africaine chez les ânes au Burkina Faso M.
Savadogo, A. Sow, L. D. Dahourou, A. Résumé Le virus de la peste équine africaine (PEA) provoque des épizooties sévères lorsqu’il est transmis aux chevaux par ses vecteurs, les culicoïdes. PARASITES & VECTORS 08/06/18 Spatial distribution modelling of Culicoides (Diptera: Ceratopogonidae) biting midges, potential vectors of African horse sickness and bluetongue viruses in Senegal. The identification of suitable areas for five targeted Culicoides species in Senegal was performed with three different modelling techniques: a spatial interpolation method, kriging and two statistical modelling methods using meteorological and environmental variables, GLM and RF models. Interpolation by kriging yielded incomplete prediction maps. To obtain complete maps, more intensive entomological survey would be necessary, especially for C. bolitinos and C. enderleini. Given the logistical efforts required to conduct such survey and identify Culicoides species, this option seems unrealistic.
MIDRANDREPORTER_CO_ZA 26/06/19 African Horse Sickness takes its toll. Cypriana survived her bout of African horse sickness, although treatment was expensive.
Photo: Supplied Across Gauteng, a total of 236 cases of African horse sickness (AHS) have been reported between 1 January and 18 June this year, according to the Gauteng Department of Agriculture and Rural Development – and the illness has also hit closer to home. The historic and internationally recognised horses of the South African Lipizzaners non-profit organisation (NPO), located in Kyalami, have been affected by the virus.
Med Vet Entomol. 2019 Jun 7. Culicoides species as potential vectors of African horse sickness virus in the southern regions of South Africa. African horse sickness (AHS), a disease of equids caused by the AHS virus, is of major concern in South Africa.
With mortality reaching up to 95% in susceptible horses and the apparent reoccurrence of cases in regions deemed non‐endemic, most particularly the Eastern Cape, epidemiological research into factors contributing to the increase in the range of this economically important virus became imperative. The vectors, Culicoides (Diptera: Ceratopogonidae), are considered unable to proliferate during the unfavourable climatic conditions experienced in winter in the province, although the annual occurrence of AHS suggests that the virus has become established and that vector activity continues throughout the year.
Surveillance of Culicoides within the province is sparse and little was known of the diversity of vector species or the abundance of known vectors, Culicoides imicola and Culicoides bolitinos. J Hyg (Lond). 1977 Oct; 79(2): 279–298. Possible spread of African horse sickness on the wind. Bulletin of Animal Health and Production in Africa - 2007 - Impact Economique de L’epizootie de Peste Equine de 2007 au Senegal. BMC 01/08/18 Sero-epidemioloical survey on African horse sickness virus among horses in Khartoum State, Central Sudan. Annals of Tropical Medicine & Parasitology - 1995 - The transmission and geographical spread of African horse sickness and bluetongue viruses. MAPA (Espagne) - MARS 2013 - MANUAL PRÁCTICO DE OPERACIONES EN LA LUCHA CONTRA LA PESTE EQUINA AFRICANA (PEA)
1 MINISTERIO DE AGRICULTURA, ALIMENTACIÓN Y MEDIO AMBIENTE SECRETARÍA GENERAL DE AGRICULTURA Y ALIMENTACIÓN DIRECCIÓN GENERAL DE SANIDAD DE LA PRODUCCIÓN AGRARIA SUBDIRECCIÓN GENERAL DE SANIDAD E HIGIENE ANIMAL Y TRAZABILIDAD MANUAL PRÁCTICO DE OPERACIONES EN LA LUCHA CONTRA LA PESTE EQUINA AFRICANA (PEA) Rev. Septiembre C/ Almagro, MADRID TEL: FAX: 2 El presente manual tiene por objeto servir como Guía de trabajo a los Servicios Veterinarios Oficiales en caso de Sospecha y de Confirmación de Foco de Peste Equina Africana (PEA), así como en su lucha contra los Vectores de enfermedad. Este manual deberá utilizarse junto con el Plan Coordinado Estatal de Alerta Sanitaria Veterinaria y la normativa vigente en materia de Sanidad y Bienestar Animal. 2 5 SECCION 1.
POLITICA DE CONTROL Las medidas de prevención y lucha contra la enfermedad adoptadas en España se enmarcan en la política de la Unión Europea (UE) en materia de sanidad animal. 7 SECCION 2. 11 SECCION 3. 16 SECCION 4. 19 SECCIÓN 5. Vet Ital. 2015 Jan-Mar;51(1):17-23. Orbivirus detection from Culicoides collected on African horse sickness outbreaks in Namibia. Journal of General Virology (2000), 81, 831-837. Identification and differentiation of the nine African horse sickness virus serotypes by RT–PCR amplification of the serotype-specific genome segment 2.
C. Sailleau 1; C. Hamblin 2; J. T. Paweska 3; S. Zientara 1 Agence Française de Sécurité Sanitaire des Aliments – Alfort, Laboratoire Central de Recherches Vétérinaires, 22 rue Pierre Curie, 94703 Maisons-Alfort, France 1 Institute for Animal Health, Pirbright Laboratory, Ash Road, Pirbright, Woking, Surrey GU24 0NF, UK 2 Onderstepoort Veterinary Institute, Private Bag X5, Onderstepoort 0110, Republic of South Africa 3.
GUIDE PRATIQUE DE DIAGNOSTIC ET DE GESTION DES EPIZOOTIES - Peste équine. MAAF/ANSES 15/05/12 Bulletin Epidémiologique de l'Anses / DGAL N°49 sur les équidés. Au sommaire: Le Laboratoire de référence de l'Union européenne pour les maladies équines autres que la peste équine. PARASITES & VECTORS 08/06/18 Spatial distribution modelling of Culicoides (Diptera: Ceratopogonidae) biting midges, potential vectors of African horse sickness and bluetongue viruses in Senegal. BMC 01/08/18 Sero-epidemioloical survey on African horse sickness virus among horses in Khartoum State, Central Sudan. FRONT. VET. SCI. 20/07/17 A Big Data Reassessment of Historical Outbreaks of Bluetongue and African Horse Sickness due to the Long-Distance Wind Dispersion of Culicoides Midges.
Introduction Bluetongue (BT) and African horse sickness (AHS) are major animal diseases affecting mostly sheep and horses, respectively (1, 2). Although the actual disease syndromes are distinct, they share much in common including a high mortality rate in susceptible animals and being transmitted by blood-feeding Culicoides spp. (family Ceratopogonidae). REV. SCI. TECH. OFF. INT. EPIZ. - 1989 - Observations on african horse sickness in donkeys in the Sudan. REV. SCI. TECH. OFF. INT. EPIZ. - 2017 - Molecular and serological surveillance of African horse sickness virus in Eastern and Central Saudi Arabia.
MEDICAL AND VETERINARY ENTOMOLOGY 27/07/17 First molecular identification of the vertebrate hosts of Culicoides imicola in Europe and a review of its blood‐feeding patterns worldwide: implications for the transmission of bluetongue disease and African ho. JOUE 19/03/18 RÈGLEMENT (UE) 2018/415 DE LA COMMISSION du 16 mars 2018 assignant des responsabilités et des tâches supplémentaires au laboratoire de référence de l'Union européenne pour la peste équine et modifiant l'annexe II de la directive 92/35/CEE du. Plant Biotechnol J. 2017 Jun 26. Immunogenicity of plant-produced African horse sickness virus-like particles: implications for a novel vaccine. J Vector Ecol. 2016 Jun;41(1):179-85. Detection of African horse sickness virus in Culicoides imicola pools using RT-qPCR.
African horse sickness (AHS) is an infectious, non-contagious arthropod-borne disease of equids, caused by the African horse sickness virus (AHSV), an orbivirus of the Reoviridae family. It is endemic in sub-Saharan Africa and thought to be the most lethal viral disease of horses. This study focused on detection of AHSV in Culicoides imicola (Diptera: Ceratopogonidae) pools by the application of a RT-qPCR. Midges were fed on AHSV-infected blood. A single blood-engorged female was allocated to pools of unfed nulliparous female midges. Pool sizes varied from 1 to 200. BMC Veterinary Research 09/09/17 The effect of alphacypermethrin-treated mesh protection against African horse sickness virus vectors on jet stall microclimate, clinical variables and faecal glucocorticoid metabolites of horses.
Alphacypermethrin-treated HDPE mesh applied to commercial jet stalls as a physical and chemical protection barrier against AHSV vectors did not compromise jet stall microclimate, clinical variables or indicators of physiological stress in horses housed under stationary stall, temperate climatic conditions. Closed top HMA-type jet stalls are commonly used to transport horses internationally. These stalls avoid potential fire alarm concerns associated with air conditioning units of climate-controlled stalls, however ventilation and microclimate could be affected by application of mesh around the stalls for protection against vectors. The outside temperatures in the present study were within or lower than a guideline range for transport of horses (10–21 °C), while the RH was higher than the recommended range (45–50%) , as expected for the overnight study conditions.
JOURNAL OF VETERINARY MEDICINE AND ANIMAL HEALTH - SEPT 2017 - A study on the sero epidemiology of African horse sickness in three woredas of Sidama Zone, Hawassa, Ethiopia. AGRICULTURE_GOV_IE - Statutory Instruments 2014 ; Au sommaire: SI 116 - African Horse Sickness Regulations 2014 (pdf 57Kb) PLOS 10/04/14 Real Time RT-PCR Assays for Detection and Typing of African Horse Sickness Virus. Abstract Although African horse sickness (AHS) can cause up to 95% mortality in horses, naïve animals can be protected by vaccination against the homologous AHSV serotype. Genome segment 2 (Seg-2) encodes outer capsid protein VP2, the most variable of the AHSV proteins.
VP2 is also a primary target for AHSV specific neutralising antibodies, and consequently determines the identity of the nine AHSV serotypes. In contrast VP1 (the viral polymerase) and VP3 (the sub-core shell protein), encoded by Seg-1 and Seg-3 respectively, are highly conserved, representing virus species/orbivirus-serogroup-specific antigens. Veterinary Research Vol. 40 No. 2 (2009) Adaptive strategies of African horse sickness virus to facilitate vector transmission.
JOURNAL OF THE SOUTH AFRICAN VETERINARY ASSOCIATION - 2013 - The 2011 outbreak of African horse sickness in the African horse sickness controlled area in South Africa. PARASITES & VECTORS - 2014 - Seasonal dynamics of Culicoides (Diptera: Ceratopogonidae) biting midges, potential vectors of African horse sickness and bluetongue viruses in the Niayes area of Senegal.
PLOS 12/11/14 Worldwide Niche and Future Potential Distribution of Culicoides imicola, a Major Vector of Bluetongue and African Horse Sickness Viruses. Vet Med Sci. 2017 Mar 6;3(2):82-90. Seroprevalence and risk factor analysis for exposure to equine encephalosis virus in Israel, Palestine and Jordan. CDC EID - DEC 2016 - Au sommaire: African Horse Sickness Caused by Genome Reassortment and Reversion to Virulence of Live, Attenuated Vaccine Viruses, South Africa, 2004–2014. Camilla T. Weyer, John D. Grewar, Phillippa Burger, Esthea Rossouw, Carina Lourens, Christopher Joone, Misha le Grange, Peter Coetzee, Estelle H. Venter, Darren P. Martin, N. James MacLachlan, and Alan J. . ( Author affiliations: University of Pretoria, Onderstepoort, South Africa (C.T. Suggested citation for this article Abstract. VIROLOGY JOURNAL 02/07/16 Requirements and comparative analysis of reverse genetics for bluetongue virus (BTV) and African horse sickness virus (AHSV)
Parasites & Vectors 25/11/15 Can insecticide-treated netting provide protection for Equids from Culicoides biting midges in the United Kingdom? RESPE via YOUTUBE 04/05/16 Journée iRESPE - Peste équine : Maladie de Schmallenberg et Fièvre catarrhale ovine. PLOS 12/11/14 Worldwide Niche and Future Potential Distribution of Culicoides imicola, a Major Vector of Bluetongue and African Horse Sickness Viruses. MERCK VETERINARY MANUAL - African Horse Sickness: Introduction. AFSCA 29/05/13 La Belgique obtient le statut «officiellement indemne de peste équine» Advances in Animal and Veterinary Sciences 1 (3): 84 – 87 2013 Seroprevalence of African Horse Sickness at Central Highland of E.
Advances in Animal and Veterinary Sciences 1 (3): 84 – 87 2013 Seroprevalence of African Horse Sickness at Central Highland of Ethiopia – guatemalt
PLOS 05/08/11 Transmission and Control of African Horse Sickness in The Netherlands: A Model Analysis. Veterinary Research - Vol. 41, No. 6 (November–December 2010) - Emerging and re-emerging animal viruses. Journal of General Virology (2000), 81, 831-837. Identification and differentiation of the nine African horse sickness virus ser. CIDRAP - Animal Diseases - African Horse Sickness J. FAO EMPRES - Bibliographies FAO. African Horse Sickness Trust. ANSES 2005 Rapport sur l’évaluation du risque d’apparition et de développement de maladies animales compte tenu d’un éventuel réchauffement climatique. Course: Ensemble des polycopiés de maladies contagieuses.