AVIAN PATHOLOGY - 2001 - The use of serotype 1- and serotype 3-specific polymerase chain reaction for the detection of Marek's disease virus in chickens. WebImagesPlus… Connexion Recherche avancée Scholar Recherche avancée Articles contenant ex. : "P Flajolet" ou J Fauvet ex. : Journal de la Société de biologie ou Revue Romane ex. : 1996 Scholar [PDF] tandfonline.com.
THE PIRBRIGHT INSTITUTE 26/10/16 Promising results in search for a more efficient and effective vaccine against Marek’s disease. Scientists at The Pirbright Institute have been encouraged by the results from a potential new vaccine candidate against Marek’s disease (MD).
Using a recombinant (new combinations of genetic material) adenovirus which carries a single gene from a virulent strain of Marek’s disease virus, they are hopeful that further research and trials could lead to the production of an effective MD vaccine that is cheaper and easier to produce - and crucially has no possibility of reverting to a virulent strain. Marek’s disease virus (MDV), is a highly contagious airborne pathogen that infects poultry, costing the industry around £1 billion a year. MD is currently controlled through vaccination and over 20 billion vaccine doses are administered annually worldwide. Phoenix Biomolecular Engineering Foundation USA via YOUTUBE 11/02/16 Vaccines 2015.
VETERINARY WORLD - JUNE 2016 - Diversity of Meq gene from clinical Marek’s disease virus infection in Saudi Arabia. Indian Vet. J., September 2015, 92 (9) : 78 - 80 Co-Occurrence of Marek’s Disease and Inclusion Body Hepatitis in a Broiler Parent Stock. INDIAN VET. J. - MAY 2015 - Marek’s Disease in an Amazon Parrot (Amazona sp.) POULTRYSITE 13/06/16 Successful Marek’s Disease Vaccination: The Devil is in the Details. Poultry News Successful Marek’s Disease Vaccination: The Devil is in the Details 13 June 2016 US - Marek’s disease (MD) is a worldwide problem in broiler production, and it’s of increasing concern in poultry-dense areas where the disease challenge is high.
This is especially true for operations growing large broilers. Here on the Delmarva Peninsula, MD has been a persistent challenge since 1923, when the commercial broiler industry was founded. We’ve learned that successful MD control requires vigilance and a carefully planned and administered MD vaccination program. Before we discuss vaccination programs, however, let’s briefly review the disease’s etiology and its effect on poultry operations.Condemnations MD, caused by an oncogenic alphaherpesvirus, results in neuropathy and lymphomatous tumors of the skin and internal organs in older broilers.
In the Delmarva region, leukosis condemnations peak in May, when the last winter-started flock is processed. Roaster challenge. MERIAL via POULTRYSITE 09/08/16 Global Patterns of Marek’s Disease Spread and Vaccination. Featured Articles Global Patterns of Marek’s Disease Spread and Vaccination 09 August 2016 Marek's disease is an important affliction of poultry flocks worldwide, and can cause mortality rates of up to 100 per cent.
A speaker at Merial's Global Avian Forum, in Barcelona in April this year, discussed the prevalence and spread of the disease across the globe. POULTRY SITE 17/11/15 Marek’s Disease in Small Flocks. Featured Articles Marek’s Disease in Small Flocks 17 November 2015 Christine Heinrichs is a freelance agricultural journalist based the US.
She's the author of How to Raise Chickens and How to Raise Poultry, and a regular contributor to a variety of poultry publications. AVIAN PATHOLOGY 10/08/15 The epizootiology of Marek's disease 2. The effect of supply flock, rearing, house and production house on the incidence of Marek's disease. USDA - AOUT 2014 - Developing Tools To Fight Marek’s Disease. New testsand vaccines are making it easier to detect viruses in chickens and protect them from the cancer-like diseases some of them cause.
One of the latest tools developed by scientists at the Agricultural Research Service’s Avian Disease and Oncology Laboratory (ADOL) in East Lansing, Michigan, is a modified polymerase chain reaction (PCR) test to detect unique genetic sequences of both Marek’s disease and avian reticuloendotheliosis viruses in various tissues from chickens. Marek’s disease is caused by a highly contagious herpes virus that primarily affects young adult chickens. It causes severe production losses and usually death and is spread from bird to bird by contaminated dust and dander in chicken houses. Avian reticuloendotheliosis, a retrovirus, infects a broader host range—chickens, turkeys, ducks, geese, and quail.
It can also cause tumors, production losses, and death in affected birds. IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS) - AVRIL 2014 - Detection of Marek’s disease virus meq gene in Feather follicle by Loop-mediated Isothermal Amplification. Veterinary Microbiology Volume 177, Issues 1–2, 15 May 2015, Pathogenic characteristics of Marek's disease virus field strains prevalent in China and the effectiveness of existing vaccines against them. A Northeast Agricultural University, Harbin 150030, PR Chinab Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, PR China Received 6 May 2014, Revised 17 December 2014, Accepted 21 December 2014, Available online 2 January 2015 Choose an option to locate/access this article: Check if you have access through your login credentials or your institution Check access doi:10.1016/j.vetmic.2014.12.020 Get rights and content Highlights MDV strains were isolated from the feather pulps of Chinese vaccinated flocks.
The CVI988 vaccine provides good protection against the LCC and LLY strains. The CVI988 vaccine cannot effectively protect against the LTS strain. Abstract The virulence of Marek's disease virus (MDV) is continuously evolving, and more virulent MDV pathotypes are emerging, thereby reducing the effectiveness of the existing vaccines. Keywords. Vet Res. 2014; 45(1): 36. Marek’s disease virus and skin interactions. BMC 23/07/15 Outbreak of Marek’s disease in a vaccinated broiler breeding flock during its peak egg-laying period in China. Marek’s disease is one of the most significant infectious diseases in poultry.
In birds, it can result in tumours or immunosuppression, making the birds more sensitive to other pathogens. Although MD vaccines have been widely used in China for a long time, failures of MD vaccination occur frequently on some poultry farms. The improper selection of a vaccine could be the cause of vaccine failure . Birds are also more susceptible to MDV mutants that have emerged in regions with more-virulent strains than to previous MDV isolates. The pp38 gene encodes a phosphoprotein of approximately 38 kDa that is necessary for both cell transformation and viral reactivation in the latent period , .
The MEQ protein, which is considered to be the major factor responsible for the occurrence of tumours, contains 339 amino acids . The mutations and increasing virulence of MDV are thought to be responsible for the occurrence of MD on vaccinated farms. BMC 23/07/15 Outbreak of Marek’s disease in a vaccinated broiler breeding flock during its peak egg-laying period in China. UNIVERSITE de François Rabelais TOURS - Thèse 2000-2001 Expression et caractérisation de quatre protéines du virus de la maladie.
UNIVERSITE de François Rabelais TOURS - Thèse 2000-2001 Expression et caractérisation de quatre protéines du virus de la maladie de Marek homologues aux protéines majeures de tégument VP22, VP16, VP13/14 et VP11/12 du virus HSV-1. – guatemalt
OIE - Code sanitaire 2010 - Maladie de Marek. Avian Diseases 57(2s1):483-490. 2013 Current Status of Marek's Disease in the United States and Worldwide Based on a Questionnai. Revue Méd. Vét., 2013, 164, 3, 106-111 Etude lésionnelle de la maladie de Marek chez le poulet de chair et chez les reproducteur.
Revue Méd. Vét., 2013, 164, 3, 106-111 Etude lésionnelle de la maladie de Marek chez le poulet de chair et chez les reproducteurs dans l’Est algérien – guatemalt
POULTRYSITE 11/11/13 Progress on Control of Marek's Disease Discussed at US Veterinary Convention. Featured Articles Progress on Control of Marek's Disease Discussed at US Veterinary Convention 11 November 2013. Epidemics Volume 5, Issue 4, December 2013, Pages 208–217 The effectiveness of mass vaccination on Marek's disease virus (MDV) o. Open Access Highlights Mathematical model to predict the outcome of broiler chicken with and without vaccination after exposure to MDV.
Epidemics Volume 5, Issue 4, December 2013, Pages 208–217 The effectiveness of mass vaccination on Marek's disease virus (MDV) outbreaks and detection within a broiler barn: A modeling study – guatemalt
Chance of MDV outbreak within a barn increases with the virulence of an MDV strain.
Vaccination significantly reduces the chance of an MDV outbreak. Mortality due to MDV is an insufficient metric to assess the prevalence of MDV. Abstract.