CDC EID - AOUT 2020 - Visceral Leishmaniasis Caused by Leishmania donovani Zymodeme MON-37, Western Ghats, India. Disclaimer: Early release articles are not considered as final versions.
You can change your cookie settings at any time. <a href=" Find out more</a> Skip to Main Content Sign In Register. JOURNAL OF ARTHROPOD-BORNE DISEASES 05/05/16 Measures to Control Phlebotomus argentipes and Visceral Leishmaniasis in India. Addy M, Nandy A (1992) Ten years of kala- azar in West Bengal, part I: did post- kala-azar dermal leishmaniasis initiate the outbreak in 24-Parganas?
Bull World Health Org. 70(3): 341–346. Alvar J, Yactayo S, Bern C (2006) Leish- maniasis and poverty. Trends Parasi- tol. 22(12): 552–557. Alvar J, Vélez ID, Bern C, Herrero M, Desjeux P, Cano J, Jannin J, den Boer M, WHO Leishmaniasis Control Team (2012) Leishmaniasis worldwide and global estimates of its incidence. PLoS One. 7(5): e35671. Beard J (2006) DDT and human health. Journal of Scientometric Res. 2018; 7(1):38-44 India’s Contribution and Research Impact in Leishmaniasis Research: A Bibliometric Analysis. Parasit Vectors. 2018; 11: 220. Trends in spatio-temporal dynamics of visceral leishmaniasis cases in a highly-endemic focus of Bihar, India: an investigation based on GIS tools. PLOS 27/09/18 Atypical leishmaniasis: A global perspective with emphasis on the Indian subcontinent. Abstract Background.
PLOS 12/10/17 Towards elimination of visceral leishmaniasis in the Indian subcontinent—Translating research to practice to public health. Citation: Hirve S, Kroeger A, Matlashewski G, Mondal D, Banjara MR, Das P, et al. (2017) Towards elimination of visceral leishmaniasis in the Indian subcontinent—Translating research to practice to public health.
Alvar, I.D. Vélez, C. Bern, M. PLOS 04/08/16 Transmission Dynamics of Visceral Leishmaniasis in the Indian Subcontinent – A Systematic Literature Review. Abstract Background As Bangladesh, India and Nepal progress towards visceral leishmaniasis (VL) elimination, it is important to understand the role of asymptomatic Leishmania infection (ALI), VL treatment relapse and post kala-azar dermal leishmaniasis (PKDL) in transmission.
Methodology/ Principal Finding We reviewed evidence systematically on ALI, relapse and PKDL. PLoS Negl Trop Dis. 2017 Feb Asymptomatic leishmaniasis in kala-azar endemic areas of Malda district, West Bengal, India. Abstract Asymptomatic leishmaniasis may drive the epidemic and an important challenge to reach the goal of joint Visceral Leishmaniasis (VL) elimination initiative taken by three Asian countries.
The role of these asymptomatic carriers in disease transmission, prognosis at individual level and rate of transformation to symptomatic VL/Post Kala-azar Dermal Leishmaniasis (PKDL) needs to be evaluated. Asymptomatic cases were diagnosed by active mass survey in eight tribal villages by detecting antileishmanial antibody using rK39 based rapid diagnostic kits and followed up for three years to observe the pattern of sero-conversion and disease transformation. Out of 2890 total population, 2603 were screened.
Antileishmanial antibody was detected in 185 individuals of them 96 had a history of VL/PKDL and 89 without such history. Author summary. PLOS 17/08/16 Efficacy, Safety and Cost of Insecticide Treated Wall Lining, Insecticide Treated Bed Nets and Indoor Wall Wash with Lime for Visceral Leishmaniasis Vector Control in the Indian Sub-continent: A Multi-country Cluster Randomized Controlled Tr. Abstract Background We investigated the efficacy, safety and cost of lime wash of household walls plus treatment of sand fly breeding places with bleach (i.e. environmental management or EM), insecticide impregnated durable wall lining (DWL), and bed net impregnation with slow release insecticide (ITN) for sand fly control in the Indian sub-continent.
Methods This multi-country cluster randomized controlled trial had 24 clusters in each three sites with eight clusters per high, medium or low sand fly density stratum. Every cluster included 45–50 households. Findings Sand fly mortality [mean and 95%CI] ranged from 84% (81%-87%) at one month to 74% (71%-78%) at 12 months for DWL, 75% (71%-79%) at one month to 49% (43%-55%) at twelve months for ITN, and 44% (34%-53%) at one month to 22% (14%-29%) at twelve months for EM. Interpretation DWL is the most effective, durable and acceptable control method followed by ITN. Author Summary Copyright: © 2016 Mondal et al. Introduction Methods Control arm. Indian J Med Res 136, July 2012, pp 22-31 Vector control interventions for visceral leishmaniasis elimination initiative in South Asia, 2005-2010.
MSF India via YOUTUBE 30/10/15 Kala Azar: Road to Elimination. THE LANCET - DEC 2016 - Elimination of visceral leishmaniasis on the Indian subcontinent. THEWIRE 19/05/17 Three-Nation Effort, Including India, to Beat Kala Azar Faced With New Challenge. In 2005, India, Nepal and Bangladesh launched a joint kala azar elimination initiative to bring down the incidence to less than 1 case per 10,000 people by 2015. That goal has not been reached. Leishmania donovani. Credit: Wikimedia Commons A South Asian drive to eliminate kala azar, a form of the disease called leishmaniasis, is already two years past its original deadline. And it could be tougher than initially thought as people who carry the parasite but do not show symptoms for up to (and sometimes beyond) three years serve as hidden reservoirs.
Leishmaniasis is caused by the parasite Leishmania donovani and spreads by the bites of certain types of sandflies. When the infection strikes the skin, it’s called cutaneous leishmaniasis; mucosal when it strikes the mucous lining (mainly of the nose and mouth); visceral when it strikes the abdomen. Treatment often relies on drugs such as miltefosine and amphotericine. Infections without symptoms Drug resistance and other challenges. PLOS 26/01/17 Investments in Research and Surveillance Are Needed to Go Beyond Elimination and Stop Transmission of Leishmania in the Indian Subcontinent. Citation: Olliaro PL, Shamsuzzaman TAKM, Marasini B, Dhariwal AC, Be-Nazir A, Mondal D, et al. (2017) Investments in Research and Surveillance Are Needed to Go Beyond Elimination and Stop Transmission of Leishmania in the Indian Subcontinent. PLoS Negl Trop Dis 11(1): e0005190. doi:10.1371/journal.pntd.0005190 Editor: Diana N.
J. PLOS 02/03/15 Arsenic Exposure and Outcomes of Antimonial Treatment in Visceral Leishmaniasis Patients in Bihar, India: A Retrospective Cohort Study. Abstract Background In the late twentieth century, emergence of high rates of treatment failure with antimonial compounds (SSG) for visceral leishmaniasis (VL) caused a public health crisis in Bihar, India. We hypothesize that exposure to arsenic through drinking contaminated groundwater may be associated with SSG treatment failure due to the development of antimony-resistant parasites.
Methods A retrospective cohort design was employed, as antimony treatment is no longer in routine use. Results. Tropical Medicine & International Health Volume 15, Issue 1, pages 60–67, January 2010 Determinants of bednet ownership and use in visceral leishmaniasis-endemic areas of the Indian subcontinent. Summary Objective To document ownership and use of bednets with its determinants in the visceral leishmaniasis (VL)-endemic region where mainly non-insecticide impregnated nets are available through commercial channels, and bednets are being considered as a leishmaniasis vector control measure. Methods In August–September 2006, semi-structured household (HH) questionnaires and observation guides were used in a random sample of 1330 HHs in VL-endemic districts of India and Nepal to collect data on VL knowledge, HH socio-economic status, bednet ownership and use patterns.
An asset index was constructed to allow wealth ranking of the HH. A binary logistic response General Estimating Equations model was fitted to evaluate the determinants of bednet ownership and use. Results The proportion of HHs with at least one bednet purchased on the commercial market was 81.5% in India and 70.2% in Nepal. Introduction Results Figure 1. Download figure to PowerPoint. Tropical Medicine & International Health Volume 15, Issue Supplement s2, pages 29–35, July 2010 Risk factors for visceral leishmaniasis in India: further evidence on the role of domestic animals. PLOS 29/11/11 Visceral Leishmaniasis in the Indian Subcontinent: Modelling Epidemiology and Control. Abstract Background In the Indian subcontinent, about 200 million people are at risk of developing visceral leishmaniasis (VL).
In 2005, the governments of India, Nepal and Bangladesh started the first regional VL elimination program with the aim to reduce the annual incidence to less than 1 per 10,000 by 2015. A mathematical model was developed to support this elimination program with basic quantifications of transmission, disease and intervention parameters. This model was used to predict the effects of different intervention strategies. Methods and Findings Parameters on the natural history of Leishmania infection were estimated based on a literature review and expert opinion or drawn from a community intervention trial (the KALANET project). Conclusions Treatment of Kala-azar is necessary on the level of the individual patient but may have little effect on transmission of parasites. Author Summary Figures Editor: Alison P. Copyright: © 2011 Stauch et al. Introduction Disease. Journal of Tropical Medicine Volume 2011 (2011), Toolkit for Monitoring and Evaluation of Indoor Residual Spraying for Visceral Leishmaniasis Control in the Indian Subcontinent: Application and Results.
CDC EID – OCT 2012 – Visceral Leishmaniasis in Rural Bihar, India. Tropical Medicine & International Health Volume 15, Issue Supplement s2, pages 50–54, July 2010 Household cost-of-illness of visceral leishmaniasis in Bihar, India. Rajendra Memorial Research Institute of Medical Sciences (ICMR) - 2012 - The burden of visceral leishmaniasis in India: Challenges in using remote sensing and GIS to understand and control.