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Informations générales et fiches toxicologiques

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TOXINS 03/06/21 Aflatoxins: History, Significant Milestones, Recent Data on their Toxicity and Ways to Mitigation. In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults died by hitherto unknown turkey “X” disease in England.

TOXINS 03/06/21 Aflatoxins: History, Significant Milestones, Recent Data on their Toxicity and Ways to Mitigation

The disease was associated with Brazilian groundnut meal affected by Aspergillus flavus. The toxin was named Aspergillus flavus toxin—aflatoxin. Rev. Saúde Pública vol.36 no.3 São Paulo June 2002 Aflatoxinas e ocratoxina A em alimentos e riscos para a saúde humana. Aflatoxinas e ocratoxina A em alimentos e riscos para a saúde humana Aflatoxins and ochratoxin A in food and the risks to human health Eloisa Dutra Caldasa, Saulo Cardoso Silvab e João Nascimento Oliveirab aFaculdade de Ciências da Saúde da Universidade de Brasília.

Rev. Saúde Pública vol.36 no.3 São Paulo June 2002 Aflatoxinas e ocratoxina A em alimentos e riscos para a saúde humana

Brasília, DF, Brasil. bLaboratório Central de Saúde Pública do Distrito Federal. DAILY MONITOR (UG) 22/03/21 The real threat of aflatoxins in your food. Although Kenya has lifted the ban on Ugandan maize, the concern that the maize contains aflatoxins, remains.

DAILY MONITOR (UG) 22/03/21 The real threat of aflatoxins in your food

The National Cancer Institute, USA, defines aflatoxins as a family of toxins produced by certain fungi that are found on agricultural crops such as maize (corn), peanuts, cottonseed, and tree nuts. These types of fungi are abundant in warm and humid regions of the world and can contaminate crops in the field, at harvest, and during storage. Consumption of food contaminated with these mycotoxins poses a serious health threat to humans and livestock. An estimated 25 per cent or more of the world’s food crops are destroyed annually in the fight against aflatoxins, according to the World Health Organisation (WHO).

Journal of Occupational Medicine and Toxicology 21/11/19 Global scientific trends on aflatoxin research during 1998–2017: a bibliometric and visualized study. EFSA 09/03/20 Risk assessment of aflatoxins in food. FRONT. MICROBIOL. 17/09/19 Aflatoxins in food and feed: An overview on prevalence, detection and control strategies. 1School of Exercise and Nutrition Sciences, Deakin University, Australia 2Department of Biotechnology, Yeungnam University, South Korea 3Department of Forestry, North Eastern Regional Institute of Science and Technology, India 4Independent researcher, India 5North Eastern Regional Institute of Science and Technology, India Aflatoxins produced by the Aspergillus species are highly toxic, carcinogenic, and cause severe contamination to the food sources leading to serious health consequences.

FRONT. MICROBIOL. 17/09/19 Aflatoxins in food and feed: An overview on prevalence, detection and control strategies

Contaminations by aflatoxins have been reported in food and feed such as groundnuts, millet, sesame seeds, maize, wheat, rice, fig, spices and cocoa because of fungal infection during pre- and post-harvest condition. Commercial products like peanut butter, cooking oil and cosmetics are also reported to be contaminated by aflatoxins besides the food products.

Even the low concentration of aflatoxins is hazardous for human and livestock. Received: 07 Jul 2019; Accepted: 17 Sep 2019. INTECH 05/10/11 Aflatoxins and Their Impact on Human and Animal Health: An Emerging Problem. NATIONAL AVIATION UNIVERSITY, KYIV - 2015 - AFLATOXINS AS NATURAL CONTAMINANTS OF IMPORTANT AGRICULTURAL COMMODITIES. CHEMISTRY via INTECH 30/08/17 Aflatoxin - Control, Analysis, Detection and Health Risks. AFLASAFE 19/10/17 Commercialisation catwalk: market-ready Aflasafe® hits ‘The Road out of Poverty’ on the world stage. Food Control Volume 76, June 2017, Innovative technologies to manage aflatoxins in foods and feeds and the profitability of application – A review. Aflatoxins are mainly produced by certain strains of Aspergillus flavus, which are found in diverse agricultural crops.

Food Control Volume 76, June 2017, Innovative technologies to manage aflatoxins in foods and feeds and the profitability of application – A review

In many lower-income countries, aflatoxins pose serious public health issues since the occurrence of these toxins can be considerably common and even extreme. Aflatoxins can negatively affect health of livestock and poultry due to contaminated feeds. Additionally, they significantly limit the development of international trade as a result of strict regulation in high-value markets. EFSA 30/06/09 Effects on public health of an increase of the levels for aflatoxin total from 4 µg/kg to 10 µg/kg for tree nuts other than almonds, hazelnuts and pistachios - Statement of the Panel on Contaminants in the Food Chain.

FRONTIERS IN MICROBIOLOGY 23/12/16 Aflatoxins: a global concern for food safety, human health and their management. FEMS Microbiol Rev. 2013 Jan;37(1):94-109. Aflatoxins, fumonisins, and trichothecenes: a convergence of knowledge. American Journal of Food and Nutrition, 2015, Vol. 3, No. 1, 12-20 Implication of Aflatoxin Contamination in Agricultural Products. BAÜ Fen Bil. Enst. Dergisi Cilt 17(2) 1-14 (2015) HACCP Sistemi Uygulaması ile Fındık Küspesindeki Aflatoksinin Kontrolü. JOURNAL OF TOXICOLOGY - 2004 - Cultural Methods for Aflatoxin Detection. CORNELL UNIVERSITY - AFLATOXINS : Occurrence and Health Risks. AFLATOXINS : Occurrence and Health Risks Aflatoxins are toxic metabolites produced by certain fungi in/on foods and feeds.

CORNELL UNIVERSITY - AFLATOXINS : Occurrence and Health Risks.

They are probably the best known and most intensively researched mycotoxins in the world. Agricultural Science - 2013 - The Analysis of a Feed Component Imported into South Africa for Aflatoxin in Relation to Fungal an. Life Science Journal 2013; 10(4) Aflatoxin and Ochratoxin A residues in some meat additives. KANSAS STATE UNIVERSITY - Présentation : Aflatoxin: What is it, and why worry? Indian J.Pharm.Biol.Res. 2013; 1(4):148-151 Aflatoxin Contamination in Agricultural Commodities. BFR 04/03/13 Transfer of aflatoxins to milk, eggs, meat and offal. INTECH 23/01/13 Aflatoxins - Recent Advances and Future Prospects. UNIVERSITE JOSEPH FOURIER - 1983 - Thèse en ligne : Contribution à l'étude des mycotoxines (aflatoxines, ochratoxines, zearaleno.

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCE AND HEALTH CARE - AVRIL 2012 - AFLATOXIN AND PUBLIC HEALTH – A POPULATION STUDY. INTECH - OCT 2011 - Aflatoxins: Their Measure and Analysis. STUDIES IN MYCOLOGY 30/06/11 Two new aflatoxin producing species, and an overview of Aspergillus section Flavi. Phylogenetic analysis We examined the genetic relatedness of section Flavi isolates using sequence analysis of the ITS region of the ribosomal RNA gene cluster, and parts of the calmodulin and β-tubulin genes.

STUDIES IN MYCOLOGY 30/06/11 Two new aflatoxin producing species, and an overview of Aspergillus section Flavi

During analysis of part of the β-tubulin gene, 561 characters were analysed, among which 223 were found to be phylogenetically informative. One of the 57 MP trees based on partial β-tubulin genes sequences is shown in Fig. 1 (tree length: 544 steps, consistency index: 0.7279, retention index: 0.9051). The calmodulin data set included 583 characters, with 221 parsimony informative characters. One of the 485 MP trees based on partial calmodulin gene sequences is shown in Fig. 2 (tree length: 557, consistency index: 0.7181, retention index: 0.9026). Phylogenetic analysis of ITS, calmodulin and β-tubulin sequence data indicated that the “A. caelatus” isolate CBS 117616 is closely related to, but phylogenetically distinct from A. caelatus (Figs 1, 2, 3).

Fig. 1. Fig. 2. Fig. 3. Fig. 4. Aflatoxin.info. Aflatoxine. Un article de Wikipédia, l'encyclopédie libre.

Aflatoxine

L'aflatoxine est une mycotoxine produite par des champignons proliférant sur des graines conservées en atmosphère chaude et humide. Elle est nuisible aussi bien chez l'homme que chez l'animal, et possède un pouvoir cancérigène élevé. Elle fut découverte en 1960 en Angleterre. Production des aflatoxines[modifier | modifier le code] Les aflatoxines constituent un groupe de 18 composés structurellement proches (un assemblage d'une coumarine et de 3 furannes).

Effets généraux des aflatoxines[modifier | modifier le code] Toxicologie[modifier | modifier le code] Aflatoxin. Aflatoxins are naturally occurring mycotoxins that are produced by Aspergillus flavus and Aspergillus parasiticus, species of fungi.

Aflatoxin

The name was created around 1960 after the discovery that the source of turkey X disease was Aspergillus flavus toxins.[1] Aflatoxins are toxic and among the most carcinogenic substances known.[2] After entering the body, aflatoxins may be metabolized by the liver to a reactive epoxide intermediate or hydroxylated to become the less harmful aflatoxin M1. Major types of aflatoxins and their metabolites[edit] At least 14 different types of aflatoxin are produced in nature.[3] Aflatoxin B1 is considered the most toxic and is produced by both Aspergillus flavus and Aspergillus parasiticus. Aflatoxin G1 and G2 are produced exclusively by A. parasiticus. While the presence of Aspergillus in food products does not always indicate harmful levels of aflatoxin are also present, it does imply a significant risk in consumption.

Contamination conditions[edit] Notes[edit] INVS 07/11/06 BEH Numéro thématique - Fièvres hémorragiques virales. 2003 - Manuel sur l'application du Système de l'analyse des risques - points critiques pour leur maîtrise (HACCP) pour la. AFSSA - Rapport final mycotoxines 2009.