BMC VETERINARY RESEARCH 31/03/21 Study on supplemental test to improve the detection of bovine tuberculosis in individual animals and herds. Bovine tuberculosis (bTB), is a worldwide disease caused by Mycobacterium bovis (M. bovis) and affects mainly cattle but also several other species; including humans causing the zoonotic tuberculosis (TB) [1,2,3,4].
The disease is difficult to control due to the lack of an effective vaccine, the presence of wildlife reservoirs, and the absence of a diagnostic assay with sufficient sensitivity (Se) and specificity (Sp) to detect sick animals at all stages of infection [4, 5]. The success of bTB eradication and control programs is based on early detection and the removal of reactors from a herd  thus routine testing and cull strategy have been applied globally . Therefore, screening-test accuracy is critical to eradication programs. Since the late nineteenth century, the Tuberculin Skin Test (TST) has been the primary antemortem test available to support bTB eradication campaigns [9, 10]. TRANSBOUNDARY AND EMERGING DISEASES 30/03/21 The impact of an African swine fever outbreak on endemic tuberculosis in wild boar populations: A model analysis. VACCINES 29/03/21 Vaccination as a Control Tool in Bovine Tuberculosis: Social Media Monitoring to Assess Public Response to Government Policy Development and Implementation.
FRONT. VET. SCI. 18/02/21 A Meta-Analysis of the Effect of Bacillus Calmette-Guérin Vaccination Against Bovine Tuberculosis: Is Perfect the Enemy of Good? Introduction Bovine tuberculosis (bTB) is a chronic infectious disease of cattle that is predominantly caused by Mycobacterium bovis, a zoonotic agent (1).
The disease remains endemic in most low- and middle-income countries (LMICs) where it negatively impacts livestock productivity and represents a significant threat to public health. A live attenuated strain of M. bovis, the “Bacille de Calmette et Guérin” (BCG), has been used for experimental vaccination of cattle against bTB since 1913, well before its first trials in humans (2). Following Calmette and Guérin's promising early reports demonstrating safety of BCG and BCG-induced protection of cattle against experimental challenge with M. bovis, several trials were carried out in different countries in the early 20th century to better define its efficacy (3). In the last decade, research in the field has focused on identifying antigens that are present in M. bovis and absent or not immunogenic in BCG. Results. MICROORGANISMS 12/12/19 Transmission Network of Deer-Borne Mycobacterium bovis Infection Revealed by a WGS Approach.
Bovine tuberculosis (TB) is a zoonotic disease, mainly caused by Mycobacterium bovis.
France was declared officially TB free in 2001, however, the disease persists in livestock and wildlife. Among wild animals, deer are particularly susceptible to bovine TB. Here, a whole genome sequence (WGS) analysis was performed on strains with the same genetic profile—spoligotype SB0121, Multiple Loci VNTR Analysis (MLVA) 6 4 5 3 11 2 5 7—isolated from different types of outbreaks, including from deer or cattle herds, or zoological or hunting parks where the presence of infected deer was a common trait in most of them.
The results of the phylogeny based on the SNP calling shows that two sub-clusters co-exist in France, one related to deer bred to be raised as livestock, and the other to hunting parks and zoos. PLOS 10/11/20 Bovine tuberculosis prevalence and risk factors in selected districts of Bangladesh. Abstract A cross-sectional survey was conducted in selected districts of Bangladesh to estimate the prevalence of bovine tuberculosis (bTB), and to identify the risk factors for bTB.
We included 1865 farmed cattle from 79 herds randomly selected from five districts. Herd and animal level data were collected using semi-structured interviews with cattle herd owners. The single intradermal comparative tuberculin test (SICTT) was used to estimate the prevalence of bTB. The risk factors were identified using mixed-effect multiple logistic regression analyses. SCIENTIFIC REPORTS 12/08/19 Genomic Polymorphism Associated with the Emergence of Virulent Isolates of Mycobacterium bovis in the Nile Delta. FRONT. MICROBIOL. 07/05/20 Global Distribution and Evolution of Mycobacterium bovis Lineages.
Introduction Tuberculosis (TB) is the leading infectious killer in the world and approximately 10 million new cases are reported annually.
Résumé traduit : Des études antérieures ont suggéré l'existence de groupes génétiques de souches de M. bovis basés sur des marqueurs ADN limités (alias complexes clonaux), et l'évolution et l'écologie de ce pathogène n'ont été que marginalement explorées au niveau mondial. Notre analyse de divergence des données concordait avec les études précédentes rapportant des données archéologiques indépendantes de l'ancien M. bovis (squelettes infectés du sud de la Sibérie à ∼2000 ans avant le présent) et indique que M. bovis existant est originaire entre 715 et 3556 ans BP, avec une émergence ultérieure Monde et Océanie, probablement influencés par les échanges entre les pays. – guatemalt
In 2017, 1.6 million people died of TB and over 95% of these deaths occurred in low and middle-income countries (World Health Organization [WHO], 2018).
The disease is strongly linked to poverty, with its prevalence following a socioeconomic gradient within and among countries (Lönnroth et al., 2009). In addition, there is a significant, and often neglected, contributor to the global disease burden, which is the zoonotic transmission of bovine TB to humans (Olea-Popelka et al., 2017).
The WHO (World Health Organization) estimated that 142,000 new cases and 12,500 deaths occurred due to zoonotic TB in 2017 (World Health Organization [WHO], 2018), numbers that are likely underestimated due to lack of routine surveillance data from most countries (Olea-Popelka et al., 2017). Veterinary Research Communications 24/06/20 Post-mortem surveillance of bovine tuberculosis in Ireland: herd-level variation in the probability of herds disclosed with lesions at routine slaughter to have skin test reactors at follow-up test. Abernethy DA, Upton P, Higgins IM, McGrath G, Goodchild AV, Rolfe SJ, Broughan JM, Downs SH, Clifton-Hadley R, Menzies FD, De la Rua-Domenech R (2013) Bovine tuberculosis trends in the UK and the Republic of Ireland 1995–2010 Vet Rec AR, Skuce RA, Byrne AW (2018) Bovine tuberculosis in Britain and Ireland–A perfect storm?
Résumé traduit : Nous évaluons comment la taille du troupeau, le type de troupeau et l'historique bTB affectent la probabilité de réacteurs supplémentaires au test de suivi à l'aide de modèles à effets aléatoires univariables et multivariables. – guatemalt
The confluence of potential ecological and epidemiological impediments to controlling a chronic infectious disease.
Front Vet Sci 5:109. Article PubMed PubMed Central Google Scholar Byrne AW, Graham J, Brown C, Donaghy A, Guelbenzu-Gonzalo M, McNair J, Skuce R, Allen A, McDowell S (2017) Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics trade movement and co-infection. BMC Vet Res 13:400. PubMed PubMed Central Google Scholar Clegg TA, Good M, More SJ (2016) Risk factors for cattle presenting with a confirmed bTB lesion at slaughter from herds with no evidence of within-herd transmission. One Health Volume 9 JUNE 2020 Bovine tuberculosis at the human–livestock–wildlife interface and its control through one health approach in the Ethiopian Somali Pastoralists: A review.
Résumé traduit : En raison de leur mode de vie mobile, les pasteurs sont presque complètement exclus des services de santé disponibles. Cet article de revue se concentre sur la tuberculose bovine chez le pasteur éthiopien somalien. Il décrit Mycobacterium bovis chez l'homme, le bétail et la faune et comment la maladie peut être contrôlée en utilisant l'approche One Health. Une approche One Health qui prend en compte le bien-être des éleveurs, la santé de leur bétail et de l'environnement est également nécessaire pour le contrôle de la BTB. – guatemalt
Front. Vet. Sci. 01/06/20 A defined antigen skin test that enables implementation of BCG vaccination for control of bovine Tuberculosis. Sreenidhi Srinivasan1, Saraswathi Subramanian2, Sai Shankar Balakrishnan2, Kathiravan Ramaiyan Selvaraju2, Vandana Manomohan2,
FRONT. VET. SCI. 27/05/20 Potential Diagnostic Value of the Peripheral Blood Mononuclear Cell Transcriptome From Cattle With Bovine Tuberculosis. Introduction Bovine tuberculosis (bTB) is a serious disease in cattle populations that is primarily caused by Mycobacterium bovis infection (1, 2).
M. bovis infects a wide range of hosts including wild animals and humans (3, 4) and is a slow-growing pathogen that causes progressive disease (5). Despite intensive worldwide efforts, bTB remains a huge burden and threat to livestock, with more than 50 million cattle infected worldwide resulting in ~3 billion dollars in economic loss annually (6). PEERJ 03/02/20 Bovine tuberculosis breakdown duration in cattle herds: an investigation of herd, host, pathogen and wildlife risk factors.
FRONT. VET. SCI. 01/04/20 Introduction and application of the interferon-γ assay in the national bovine tuberculosis control programme in South Korea. Yun-Ho Jang1, Tae-woon Kim1, Min Kyu Jeong1, Yoon Jeong Seo1, Soyoon Ryoo2, Chan Ho Park3, Sin seok Kang4, Young Ju Lee5, Soon-Seek Yoon1 and Jaemyung Kim1* 1Bacterial Disease Division, Animal and Plant Quarantine Agency (South Korea), South Korea 2Food and Mouth Disease Division, Animal and Plant Quarantine Agency (South Korea), South Korea 3Other, South Korea 4Other, South Korea 5College of Veterinary Medicine, Kyungpook National University, South Korea Bovine tuberculosis is a chronic disease impacting both public health and the livestock industry.
The interferon (IFN)-γ assay has been introduced as an ancillary test for diagnosing bovine tuberculosis to overcome limitations of the skin test. The objective of this study was to assess the IFN-γ assay in terms of diagnostics and as a nationwide surveillance program in South Korea. Keywords: bovine tuberculosis, Mycobacterium bovis, CFT, Cattle, IFN-γ Received: 05 Nov 2019; Accepted: 01 Apr 2020. bTB in the Marajo Island, Brazil, and M. bovis genotypic diversity The initial approach to investigate the clonality and population structure of M. bovis in this setting relied on the use of classical typing methods (spoligotyping and MIRU-VNTR) in the characterization of 22 M. bovis isolates from nine cattle and nine buffalos from October 2014 to December 2015. The genotypic characterization by spoligotyping yielded two distinct profiles (Table 1): the predominant spoligotype was SB0822/SIT997, detected in 21 isolates, which is characterized by the absence of spacers 3, 4, 9, 16, and 39 to 43; the remaining isolate corresponded to the spoligotype SB0885/SIT986, which lacks spacers 3, 4, 5, 6, 9, 16 and 39 to 43.
The most common MIRU-VNTR profile was shared by 14 isolates, the second and third most common MIRU-VNTR profiles were shared by two isolates and, two isolates exhibited unique profiles and were therefore classified as non-clustered strains (Table 1). VETERINARY WORLD 13/01/20 Evaluation of adenosine deaminase activity in serum of cattle and buffaloes in the diagnosis of bovine tuberculosis.
Research (Published online: 13-01-2020) 16. Evaluation of adenosine deaminase activity in serum of cattle and buffaloes in the diagnosis of bovine tuberculosis. ELIFESCIENCES 17/12/19 Combining genomics and epidemiology to analyse bi-directional transmission of Mycobacterium bovis in a multi-host system. Essential revisions:The major required revision is to place the work in the context of clear hypotheses, predictions of these hypotheses for the results of analyses, and interpretation of the analyses as they inform our judgment on those hypotheses.
As currently written, like many pathogen genomics papers, this paper presents analyses and results, but leaves the rationale for the analyses and the interpretation of the results in terms of scientific hypotheses unclear. While this is not atypical for papers in the field, it makes it very hard for an interested non-specialist in the subject matter (ecology of M. bovis) to appreciate the paper. For a general interest journal like eLife, it is problematic because the reader is left with an unclear sense of what has and has not been shown.It seems that the major hypotheses being tested revolve around the extent to which badgers are a reservoir for cattle M. bovis infection. Thank you for highlighting this critical issue. BMC VETERINARY RESEARCH 04/12/19 Reverse zoonotic tuberculosis transmission from an emerging Uganda I strain between pastoralists and cattle in South-Eastern Nigeria.
SCIENTIFIC REPORTS 28/11/19 Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis. FRONT. VET. SCI. 15/11/19 EPIDEMIOLOGICAL STUDY OF MYCOBACTERIUM BOVIS INFECTION IN BUFFALO AND CATTLE IN AMAZONAS, BRAZIL. Paulo A. Carneiro1, 2, 3, Haruo Takatani4, Taynara N. Pasquatti5, Christian B. KOCATEPE VETERINARY JOURNAL - 2019 - Detection of Mycoplasma bovis Infection in Cattle Mammary Tissue by Immunofluorescence and qRT-PCR Methods. FRONT. VET. SCI. 06/06/19 Editorial: Bovine tuberculosis – international perspectives on epidemiology and management. 1Agri-Food and Biosciences Institute (AFBI), United Kingdom 2Michigan Department of Natural Resources, United States 3Stellenbosch University, South Africa Editorial: Bovine tuberculosis – international perspectives on epidemiology and managementAndrew W. Byrne*^1, 2, Adrian R.
Allen*1, Daniel J. O’Brien*3, Michele A. Miller*41. Theme: Modeling as a tool for understanding bTBModeling approaches were used to gain insights and make inferences on a number of different problems in bTB management. CONCLUSIONThis Research Topic was contributed to by 149 authors, representing over 15 countries. Fig. 1: Frequency weighted “word cloud” using the abstracts from the Research Topic “Bovine tuberculosis – international perspectives on epidemiology and management” CDC EID - JULY 2019 - Mycobacterium bovis Infection in African Wild Dogs, Kruger National Park, South Africa. Disclaimer: Ahead of print articles are not considered as final versions.
Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: Stellenbosch University, Cape Town, South Africa (R.L. Higgitt, G.A. Hausler, P.D. van Helden, S.D.C. Parsons, M.A. The African wild dog (Lycaon pictus) is an endangered carnivore, occurring in fragmented, small populations (in South Africa, <500 animals). OIE - REV.SCI. TECH. OFF. INT. EPIZ. - 2018 - Antibacterial activity of silver nanoparticles against field and reference strains of Mycobacterium tuberculosis, Mycobacterium bovis and multiple-drug-resistant tuberculosis strains.
BMC PUBLIC HEALTH 13/03/19 Community, system and policy level drivers of bovine tuberculosis in smallholder periurban dairy farms in India: a qualitative enquiry. FRONT. VET. SCI. 04/03/19 Validation of a Real-Time PCR for the Detection of Mycobacterium tuberculosis Complex Members in Bovine Tissue Samples. Introduction. BMC 01/03/19 Specificity of serological test for detection of tuberculosis in cattle, goats, sheep and pigs under different epidemiological situations. In this study we have evaluated the Sp of the P22 ELISA for the detection of MTC-specific antibodies. We found that optimal Sp (100%) was observed in pigs, whilst in cattle and sheep the ELISA had high Sp values (≥98%) using a stringent cut-off (150).
FRONT. VET. SCI. 07/12/18 Can We Breed Cattle for Lower Bovine TB Infectivity? Introduction. FRONT. VET. SCI. 12/11/18 Persistent Spillback Of Bovine Tuberculosis From White-tailed Deer to Cattle in Michigan, USA: Status, Strategies and Needs. JOURNAL OF VETERINARY MEDICINE - MAI 2017 - Prevalence of bovine brucellosis, tuberculosis and dermatophilosis among cattle from Benin’s main dairy basins. UNIBAS_CH - 2018 - Thèse en ligne : Prevalence, Molecular Characterization, Transmission Dynamics and Cost Analysis of Bovine Tuberculosis in Morocco. FRONT. VET. SCI 30/10/18 Whole Genome Sequencing for Determining the Source of Mycobacterium bovis Infections in Livestock Herds and Wildlife in New Zealand. Introduction. FRONT. VET. SCI. 18/10/18 Review: Roll-back eradication of bovine tuberculosis (TB) from wildlife in New Zealand: Concepts, evolving approaches and progress.
1Landcare Research, New Zealand 2OSPRI New Zealand, New Zealand The New Zealand government and agricultural industries recently jointly adopted the goal of nationally eradicating bovine tuberculosis (TB) from livestock and wildlife reservoirs by 2055. Only Australia has eradicated TB from a wildlife maintenance host. FRONT. VET. SCI. 01/10/18 Impact of Genetic Selection for Increased Cattle Resistance to Bovine Tuberculosis on Disease Transmission Dynamics. FRONT. VET. SCI. 01/10/18 Efficacy and safety of BCG vaccine for control of tuberculosis in domestic livestock and wildlife. 1The Hopkirk Research Institute, AgResearch, New Zealand 2Animal and Plant Health Agency (United Kingdom), United Kingdom 3Department of Agriculture, Forestry and Fisheries (South Africa), South Africa Bovine tuberculosis (TB) continues to be an intractable problem in many countries, particularly where “test and slaughter” policies cannot be implemented or where wildlife reservoirs of Mycobacterium bovis infection serve as a recurrent source of infection for domestic livestock.
BMC VETERINARY RESEARCH 29/09/18 Detection of a streptomycin-resistant Mycobacterium bovis strain through antitubercular drug susceptibility testing of Tunisian Mycobacterium tuberculosis complex isolates from cattle. FRONT. VET. SCI. 24/09/18 Whole genome sequencing of Mycobacterium bovis isolated from livestock in the United States, 1989-2018. FRONT. VET. SCI. 14/09/18 Use of the human vaccine, Mycobacterium bovis bacillus Calmette Guérin in deer. FRONTIERS IN VETERINARY SCIENCE 10/09/18 Impact of genetic selection for increased cattle resistance to bovine tuberculosis on disease transmission dynamics. FRONT. VET. SCI. 06/09/18 Risk of introduction of bovine tuberculosis (TB) intoTB-free herds in southern Bahia, Brazil, associated with movement of live cattle.
VETERINARY WORLD 10/05/18 A retrospective study of bovine tuberculosis at the municipal abattoir of Bauchi State, Northeastern Nigeria. FRONTIERS IN VETERINARY SCIENCE 24/07/18 Development and evaluation of a serological assay for the diagnosis of tuberculosis in alpacas and llamas. FRONTIERS IN VETERINARY SCIENCE 25/07/18 Bovine Tuberculosis Management in Northwest Minnesota and Implications of the Risk Information Seeking and Processing (RISP) Model for Wildlife Disease Management. Ann Agric Environ Med 2016;23(1):97–102 ‘TB or not TB?’ Problems of differential diagnosis of cutaneous mycobacteriosis and tuberculosis – A Case Study and interdisciplinary discussion.
III Congreso Argentine de Zoonosis - JUNIO 2014 - A One Health approach for controlling tuberculosis in animals and humans. BMC Veterinary Research 29/12/17 Bovine tuberculosis visible lesions in cattle culled during herd breakdowns: the effects of individual characteristics, trade movement and co-infection. BMC VETERINARY RESEARCH 22/12/17 Genetic diversity assessment of Tunisian Mycobacterium bovis population isolated from cattle.
BMC Veterinary Research 10/10/17 Mycobacterium tuberculosis infection in cattle from the Eastern Cape Province of South Africa. HEREDITY - 2014 - Genome-wide association study identifies novel loci associated with resistance to bovine tuberculosis. PLOS 05/07/17 Assessment of BCG and inactivated Mycobacterium bovis vaccines in an experimental tuberculosis infection model in sheep (étude espagnole) BMC Veterinary Research 22/08/17 Relative abundance of Mycobacterium bovis molecular types in cattle: a simulation study of potential epidemiological drivers. BMC Veterinary Research 2017 13:252 Field evaluation of the efficacy of Mycobacterium bovis BCG vaccine against tuberculosis in goats. Rev. Inst. Med. trop. S. Paulo vol.59 São Paulo 2017 Epub June 05, 2017 Diagnosis of mycobacteria in bovine milk: an overview.
VETERINARY MEDICINE INTERNATIONAL 03/05/17 Factors Affecting Herd Status for Bovine Tuberculosis in Dairy Cattle in Northern Thailand. Journal of Tuberculosis Research, 2017,5,77-80 Pathology of Tuberculosis in Camels (Camelus dromedaries) in the Sudan. CDC EID - MARS 2017 - Au sommaire notamment: Mycobacterium bovis in a Free-Ranging Black Rhinoceros, Kruger National Park, South Africa, 2016. Transboundary and Emerging Diseases 17/02/15 Serological Follow-up of Tuberculosis in a Wild Boar Population in Contact with Infected Cattle. Brazilian Journal of Microbiology Volume 48, Issue 1, January–March 2017, Infection by Mycobacterium bovis in a dog from Brazil. BMC VETERINARY RESEARCH 15/08/14 Bovine tuberculosis slaughter surveillance in the United States 2001–2010: assessment of its traceback investigation function. NealsYardDairyFilms via YOUTUBE 21/11/14 Progress towards new testing methods for M bovis: Bovine TB: why is it such a problem to control?
JOURNAL OF WILDLIFE DISEASES - 2017 - LIMITED ANTIBODY EVIDENCE OF EXPOSURE TO MYCOBACTERIUM BOVIS IN FERAL SWINE (SUS SCROFA) IN THE USA. PLOS 10/01/17 Tuberculosis Detection in Paratuberculosis Vaccinated Calves: New Alternatives against Interference. FRONTIERS IN VETERINARY SCIENCE 11/11/15 Tuberculosis and One Health – What is in a Name? VETERINARY RESEARCH FORUM - WINTER 2015 - Concurrent atypical diffused tuberculosis and macrorhabdosis in a canary (Serinus canaria) International Journal of Mycobacteriology Volume 4, Supplement 1, March 2015, Bovine tuberculosis in Iran: The past, present and future of a national disease control program. Veterinary Research 2013, 44:97 (16 October 2013) Age-dependent patterns of bovine tuberculosis in cattle.
Turk J Vet Anim Sci (2013) 37: 153-159 Rapid and simultaneous detection of Mycobacterium bovis and Mycobacterium avium subsp. pa. CDC EID – JUIN 2013 – Au sommaire:Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee. CDC EID – JUIN 2013 – Au sommaire:Zoonotic Mycobacterium bovis–induced Tuberculosis in Humans. Utrecht University - 2013 - Thèse en ligne : Tuberculosis in African lions. CALIFORNIA DEPARTMENT OF FOOD & AGRICULTURE - JULY 2012 - The Future of the National Bovine Tuberculosis Program.
ACTA VET. BRNO, 54,1985: 217-222 TUBERCULOUS LESIONS IN SLAUGHTER PIGS FROM THE VIEWPOINT OF FOOD HYGIENE. Epidemiol. Infect. (2011), 139, 105–112. Bovine tuberculosis: making a case for effective surveillance. Comparison of histologic techniques for the diagnosis of bovine tuberculosis in the framework of eradication programs. The Veterinary Record 163:43-47 (2008) Patterns of lesions of bovine tuberculosis in wild red deer and wild boar. Int. J. Environ. Res. Public Health 2012, 9, 2045-2056; Molecular Detection and Drug Resistance of Mycobacterium tuberculosis Co. PLOS 13/08/12 Impact of Imperfect Test Sensitivity on Determining Risk Factors: The Case of Bovine Tuberculosis. Veterinary Medicine International Volume 2012 (2012), Tuberculosis in Humans and Cattle in Jigawa State, Nigeria: Risk Factors A.
Revue Méd. Vét., 2013, 164, 2, 60-66 Detection of Corynebacterium pseudotuberculosis from sheep lymph nodes by PCR.