ALMA MATER STUDIORUM - UNIVERSITA'DI BOLOGNA - 2006 - Thèse en ligne :Effect of diet supplementation in insaturated fatty acids on meat keeping qualyties: study of selected fatty acids antimicrobial properties and inhibition mechnism on Staphyloccus aureu. RSC ADVANCES 27/07/20 Multi-omics based characterization of antibiotic response in clinical isogenic isolates of methicillin-susceptible/-resistant Staphylococcus aureus. 1.
Introduction Staphylococcus aureus, a Gram-positive bacterial species, is found asymptomatically colonizing approximately 20–30% of the healthy population in the nares, on the skin, and in the gastrointestinal tract.1 However, this species can cause very serious infection once these bacteria are able to penetrate internal tissues and/or blood vessels.2 Currently, especially, global spread of methicillin-resistant S. aureus (MRSA) is notorious for complicating the treatment of infection.1,3 Even, MRSA accounts for approximately 50% of S. aureus infection cases and becomes resistant to almost all antibiotics.1 Therefore, there is an urgent need to develop new antibiotic compounds and/or therapeutic strategies, and numerous studies are underway in an effort to control MRSA.3,4 2. Materials and methods 2.1 S. aureus strain, culture condition and oxacillin treatment.
J Glob Antimicrob Resist. 2019 Mar; Determinants of methicillin-resistant Staphylococcus aureus (MRSA) prevalence in the Asia-Pacific region: A systematic review and meta-analysis. NATURE 19/10/17 Staphylococcus aureus interaction with Pseudomonas aeruginosa biofilm enhances tobramycin resistance. Effect of S. aureus exoproducts on P. aeruginosa in a biofilm slide chamber model New onset P. aeruginosa isolates were collected from 46 patients with cystic fibrosis undergoing standardized Antibiotic Eradication Therapy with inhaled tobramycin.12,13 Thirty-three P. aeruginosa isolates were obtained from patients who underwent successful eradication therapy (eradicated isolates) and 13 isolates obtained from patients who failed eradication therapy (persistent isolates).
To assess the effect of S. aureus on P. aeruginosa, we exposed P. aeruginosa isolates to S. aureus filtrates (SaF) (bacteria-free supernatants of S. aureus). Staphylococcus aureus filtrates (SaF) do not affect initial attachment of Pseudomonas aeruginosa to borosilicate slide chambers. a Schematic representation of how SaF biofilm formation was assessed. P. aeruginosa was grown overnight in liquid culture prior to seeding in 8-well slide chambers. EUROSURVEILLANCE 24/10/13 Au sommaire: Molecular epidemiology of meticillin-resistant Staphylococcus aureus (MRSA): think regionally but use globally uniform typing languages. EUROSURVEILLANCE 24/10/13 Au sommaire: Letter to the editor: Seafarers: a new risk group for meticillin-resistant Staphylococcus aureus (MRSA)
PLOS - 2013 - The Use of Machine Learning Methodologies to Analyse Antibiotic and Biocide Susceptibility in Staphylococcus aureus. Eurosurveillance, Volume 19, Issue 29, 24 July 2014 Systematic literature analysis and review of targeted preventive measures to limit healthcare-associated infections by meticillin-resistant Staphylococcus aureus. BMC 31/03/14 Natural history of colonization with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE): a systematic review. ELIFESCIENCES 02/10/18 An essential Staphylococcus aureus cell division protein directly regulates FtsZ dynamics.
[Editors’ note: the author responses to the first round of peer review follow.]
Reviewer #1:In this manuscript, the authors analyze the function of the GpsB protein in S. aureus. GpsB and its paralog DivIVA are well-studied in Firmicutes and Actinobacteria. In these species, these two proteins have been shown to be involved in regulation of cell growth, regulation of cell division and/or in chromosome segregation. Here, it is reported that overproduction of GpsB from S. aureus in B. subtilis gives rise to filamentous cells; overproduction of GpsB in S. aureus gives rise to large spherical cells; depletion of GpsB in S. aureus results in inhibition of cell division; a gspB mutation is isolated that does not affect cell shape upon expression in B. subtilis; GpsB localization is determined and found to be dynamic over the cell cycle: and, that GpsB interacts with FtsZ in vitro.Previously, it has been reported that GpsB is essential in S. aureus.
Agreed. We agree! Agreed. Agreed. Agreed. MEDICALXPRESS 21/11/18 As antibiotic resistance grows, researchers find new targets for fighting deadly staph infections. A new look at the inner-workings of bacterial cells could help researchers overcome deadly antibiotic resistance and save the lives of tens-of-thousands of people every year.
The research, published in eLife, gives scientists a first-of-its-kind look at the essential protein molecule responsible for prompting cell division in Staphylococcus aureus, the bacterium that causes staph infections. Each year, approximately two million Americans are diagnosed with infections caused by antibiotic-resistant staph and other bacteria according to US Centers for Disease Control and Prevention.
J Clin Diagn Res. 2017 Aug; 11(8): Antimicrobial Activity of Honey with Special Reference to Methicillin Resistant Staphylococcus aureus (MRSA) and Methicillin Sensitive Staphylococcus aureus (MSSA) PLOS 15/03/18 SpdC, a novel virulence factor, controls histidine kinase activity in Staphylococcus aureus. Abstract The success of Staphylococcus aureus, as both a human and animal pathogen, stems from its ability to rapidly adapt to a wide spectrum of environmental conditions.
Two-component systems (TCSs) play a crucial role in this process. Here, we describe a novel staphylococcal virulence factor, SpdC, an Abi-domain protein, involved in signal sensing and/or transduction. We have uncovered a functional link between the WalKR essential TCS and the SpdC Abi membrane protein. Expression of spdC is positively regulated by the WalKR system and, in turn, SpdC negatively controls WalKR regulon genes, effectively constituting a negative feedback loop.
Author summary Staphylococcus aureus is a major human pathogen, and has become a significant worldwide health concern due to the rapid emergence of antibiotic resistant strains. MEDICAL PRESS 26/03/18 A new mechanism involved in Staphylococcus aureus virulence and antibiotic resistance. An Institut Pasteur-CNRS research team has characterized a Staphylococcus aureus gene involved in virulence, biofilm formation and resistance to certain antibiotics.
These results open up new avenues for understanding the control of S. aureus virulence mechanisms. This work was recently published in the journal PLoS Pathogens. Staphylococcus aureus is part of the natural skin flora, preferentially colonizing external mucosa in 30 to 50 percent of the population, healthy carriers who develop no symptoms. But it is also a major human pathogen, causing diseases ranging from skin lesions (boils, impetigo, etc.) to endocarditis, acute pneumonia, osteomyelitis or sepsis. CDC EID - FEV 2018 - Plasmid-Encoded Transferable mecB-Mediated Methicillin Resistance in Staphylococcus aureus. Author affiliations: University Hospital Münster, Münster, Germany (K.
Becker, S. van Alen, E.A. Idelevich, N. Schleimer, J. Seggewiß, A. Mellmann, U. Suggested citation for this article Abstract. Asian Journal of Plant Sciences, - 2006 - Antibacterial activity of certain Iranian medicinal plants against methicillin-resistant and sensitive Staphylococcus aureus. Dadgar, T. and Asmar, M. and Saifi, A. and Mazandarani, M. and Bayat, H. and Moradi, A. and Bazueri, M. and Ghaemi, E. (2006) Antibacterial activity of certain Iranian medicinal plants against methicillin-resistant and sensitive Staphylococcus aureus.
Asian Journal of Plant Sciences, 5 (5). pp. 861-866. Int. J. Environ. Res. Public Health 30/08/17 Antimicrobial Susceptibility of Staphylococcus aureus Isolated from Recreational Waters and Beach Sand in Eastern Cape Province of South Africa. REFLECTIONSIPC 06/06/17 LA-MRSA: On the definition of emergence. Some friends, called patriotic hackers, had secured a very interesting surveillance database and I tried to write a manuscript, when I was scooped (in CID) by friends that apparently had access to the same database.
That made my work redundant. So, for your eyes only, my take on that data. The database holds all S. aureus BSI (SAB) from Denmark from 2010 till 2016, with isolates categorized as MSSA, Live-stock Associated-MRSA (LA-MRSA) and other MRSA. International Journal of Medical Microbiology Available online 3 May 2017 Methicillin-resistant Staphylococcus aureus Screening PCR adapted to locally emerging variants—Evaluation of novel SCCmec primers. INRA 05/10/16 Staphylocoque doré : décryptage d’une stratégie de résistance à certains antimicrobiens. Le triclosan est un composé très largement utilisé dans les produits de beauté et d’hygiène (bains de bouche, dentifrices, crèmes hydratantes, gels douche) ou pour enduire les fils chirurgicaux.
Il appartient à une famille de composés antimicrobiens qui inhibent la voie de biosynthèse des acides gras (dénommée FASII pour Fatty Acid Synthesis), éléments vitaux pour les bactéries. Cette molécule étant soupçonnée d’être un perturbateur endocrinien, la Commission européenne a, en 2016, retiré le triclosan de la liste des composés approuvés comme additifs dans des produits de Type 1 (produits d’hygiène)2. Les autorités sanitaires américaines (Food and Drug administration) ont également limité son utilisation en 2016 dans la fabrication des savons antibactériens3. Cependant, ce type de molécules constitue toujours une piste privilégiée pour le développement de nouveaux antibactériens. FRONTIERS IN MICROBIOLOGY 18/10/16 Systematic Review on Global Epidemiology of Methicillin-Resistant Staphylococcus pseudintermedius: Inference of Population Structure from Multilocus Sequence Typing Data.
Introduction Staphylococcus pseudintermedius is a bacterial commensal of the skin and mucosae of dogs and also the most prevalent cause of canine bacterial infections (Bannoehr and Guardabassi, 2012). Although primarily adapted to the canine host, this coagulase-positive staphylococcal species may infect other pet animals, mainly cats (Kadlec et al., 2010), and humans (Van Hoovels et al., 2006). Multilocus sequence typing (MLST) has proven to be an invaluable DNA sequence-based technique for analysis of population structure and long-term epidemiological trends at a global level (Spratt and Maiden, 1999). A first MLST scheme based on five loci was initially proposed in 2007 to provide insight into the overall population genetic structure of the Staphylococcus intermedius Group (SIG), which includes S. intermedius and S. delphini in addition to S. pseudintermedius (Bannoehr et al., 2007). University of Denmark - MAI 2012 - Zinc resistance of Staphylococcus aureus of animal origin is strongly associated with methici.
EMA 26/09/12 Researchers discover link between use of antibiotics and MRSA. Researchers discover link between use of antibiotics and MRSA [Date: 2012-09-26] Researchers tracking a penicillin-type resistant bacterium that leads to infection in some hospital patients have discovered that occurrence falls significantly when prescriptions of a common antibiotic of the fluoroquinolone family also fall. The research team, was led by St George's, University of London, United Kingdom, has published its results in the Journal of Antimicrobial Chemotherapy.
Antibiotic resistance in the environment, with particular reference to MRSA. Toxins 2010, 2, 2117-2131 Multiple Roles of Staphylococcus aureus Enterotoxins: Pathogenicity, Superantigenic Activity, and Corr. FORMATEX - 2010 - Global resistance trends and the potential impact of Methicillin Resistant Staphylococcus aureus (MRSA) and it. The dissemination among Staphylococcus aureus of the Staphylococcal Chromosome Cassette mec (SCCmec) which confers multiresistance. New tool helps trace MRSA's local, global spread. Jan 21, 2010 (CIDRAP News) A multi-national team of researchers has applied a new genomic tool to a 50-year-old bacterial foe, using minute mutations to track the spread of drug-resistant staph both across continents and within a single hospital. On a global scale, their sleuthing tracked the movement of one clone of methicillin-resistant Staphylococcus aureus (MRSA) back and forth across the planet, pinpointing when individual cases transported infections across national borders to spark new outbreaks.
Separately, their method demonstrated that what appeared to be a hospital epidemic of MRSA was not a single outbreak, but rather a mixed event of patient-to-patient transmission of one strain that was accompanied by multiple importations from outside the hospital of similar but unrelated strains. The work was published today in Science. Harris SR, Feil EJ, Holden MTG, et al. Evolution of MRSA during hospital transmission and intercontinental spread.
Sélection de documents de l'autorité sanitaire du Danemark (DTU) BFR 15/03/09 People can become infected with methicillin-resistant Staphylococcus aureus (MRSA) through contact with livestock. Johann Wolfgang GOETHE-UNIVERSITAT - Frankfurt am Main - Staphylococcus aureus / Antibiotics. Staphylococcus aureus résistant à la méticilline. Un article de Wikipédia, l'encyclopédie libre. Microscopie électronique, colorée Rupture d'un kyste infecté par une souche MRSA. CDC EID MARS 2008 Au sommaire: Methicillin-Resistant and -Susceptible Staphylococcus aureus Sequence Type 398 in Pigs and Humans. Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options CDC Home CDC 24/7: Saving Lives. Protecting People. . ™ ASPC 22/05/08 Feuillet de renseignements – Staphylococcus aureus résistant à la méthicilline d’origine communautaire (SARM d’ori.
Pour partager cette page, veuillez cliquez sur le réseau sociale de votre choix. Qu'est-ce que le SARM d'origine communautaire? Lorsque la bactérie SARM provoque une infection chez des personnes qui n'ont été ni hospitalisées ni opérées dans la dernière année, elle s'appelle SARM d'origine communautaire. Ces infections se manifestent habituellement sous forme d'infections cutanées telles que des boutons et des furoncles et peuvent se produire chez des personnes qui, autrement, sont en bonne santé.
ASPC 22/05/08 Feuillet de renseignements – Staphylococcus aureus résistant à la méthicilline. Pour partager cette page, veuillez cliquez sur le réseau sociale de votre choix.