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SYNDROME DYSGENESIQUE ET RESPIRATOIRE DU PORC EN CHINE

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FRONT. VET. SCI. 08/04/22 Epidemiological and Genetic Characteristics of Porcine Reproductive and Respiratory Syndrome Virus in South China Between 2017 and 2021. Introduction Porcine reproductive and respiratory syndrome virus (PRRSV), the etiological agent of porcine reproductive and respiratory syndrome (PRRS), is a small, enveloped, single-stranded positive-sense RNA virus belonging to the order Nidoviridales, family Arteriviridae (1, 2).

PRRSV possesses a genome ~15 kb in length and contains at least ten open reading frames (ORFs), including ORF1a, ORF1b, ORF2a, ORF2b, ORF3, ORF4, ORF5, ORF5a, ORF6, and ORF7. Among these ORFs, the ORF1a and ORF1b encode two poly-proteins which are further cleaved into 16 nonstructural proteins (Nsp), including Nsp1α, Nsp1β, Nsp2, Nsp2TF, Nsp2N, Nsp3-6, Nsp7α, Nsp7β, and Nsp8-12. The remaining eight ORFs encode the viral structural proteins GP2a, E (2b), GP3, GP4, GP5, GP5a, M, and N, respectively (3–6). PRRSV is mainly divided into two genotypes, PRRSV2 represented by VR2332 (Accession no. AY150564), and PRRSV1 represented by Lelystad virus (Accession no. M96262) (9). Materials and Methods Table 1. Table 2. VIRUSES 16/03/20 Outbreak of Porcine Reproductive and Respiratory Syndrome Virus 1 in Taiwan.

MDPI and ACS Style Lin, W. -H.; Kaewprom, K.; Wang, S. -Y.; Lin, C. -F.; Yang, C. -Y.; Chiou, M. AMA Style Lin W-H, Kaewprom K, Wang S-Y, Lin C-F, Yang C-Y, Chiou M-T, Lin C-N. Chicago/Turabian Style Lin, Wei-Hao; Kaewprom, Kraijak; Wang, Sheng-Yuan; Lin, Chuen-Fu; Yang, Cheng-Yao; Chiou, Ming-Tang; Lin, Chao-Nan. 2020. Show more citation formatsShow less citations formats Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. MDPI and ACS Style Lin, W. AMA Style Lin W-H, Kaewprom K, Wang S-Y, Lin C-F, Yang C-Y, Chiou M-T, Lin C-N. Chicago/Turabian Style Lin, Wei-Hao; Kaewprom, Kraijak; Wang, Sheng-Yuan; Lin, Chuen-Fu; Yang, Cheng-Yao; Chiou, Ming-Tang; Lin, Chao-Nan. 2020. Show more citation formatsShow less citations formats Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. BMC Veterinary Research 24/05/19 Genetic analysis of porcine productive and respiratory syndrome virus between 2013 and 2014 in Southern parts of China: identification of several novel strains with amino acid deletions or insertions in nsp2.

Since its emergence in China at the end of 1995, PRRSV has spread widely in all areas of China and is continuously evolving. This has led to the emergence of some new antigenic variant strains [17]. In 2006, a large outbreak of porcine high fever syndrome (PHFD), caused by a highly pathogenic form of PRRSV, emerged in China and Southeast Asian countries and caused major economic losses for swine farming [12, 15, 16] . In our previous study, 133 of 475 samples (28%) were positive for PRRSV, indicating that PRRSV is widely distributed among swine populations in southern parts of China.

Fifty-six ORF5 sequences and 35 nsp2 HVR sequences were selected for investigation of variations and phylogenetic analyses for their genetic diversities. Sequences alignments of GP5 and nsp2 showed that there was extensive genetic variability between them (84.5–100% amino acid identity) or with the representative strain, VR-2332 (84.5–99.0% amino acid identity). Nsp2 is also a highly immunogenic protein. VIRUSES 27/03/18 Identification of a Novel Recombinant Type 2 Porcine Reproductive and Respiratory Syndrome Virus in China.

Microb Pathog. 2017 Aug;109:20-28. Molecular epidemiology of porcine reproductive and respiratory syndrome virus in Central China since 2014: The prevalence of NADC30-like PRRSVs. JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Highlights The NADC30-like PRRSV strains have been circulating and prevalent in Central China. The classic HP-PRRSV strains are still circulating in pig farms of Central China and relatively conserved in recent years characterized by the highly similarity between each other. The NADC30-like PRRSV strains underwent rapid evolution and contained extensive amino acid substitutions in important motifs of GP5, such as major neutralizing epitope, potential N-glycosylation and signal peptides, which might be involved in viral virulence and immune escape.

Our data would contribute to epidemiology investigation of PRRSV and have some implications for vaccine development. Abstract Porcine reproductive and respiratory syndrome (PRRS), characterized by respiratory disorders in piglets and reproductive failure in sows, is still the great threat of swine industry. Keywords Phylogenetic analysis Nsp2. VIROLOGY JOURNAL 04/01/18 The prevalent status and genetic diversity of porcine reproductive and respiratory syndrome virus in China: a molecular epidemiological perspective.

Porcine reproductive and respiratory syndrome (PRRS) is one of the most important economically diseases to the swine industry worldwide. It is estimated that the total economic losses caused by PRRS is about $664 million annually in the America, an increase from the $560 million annual cost estimated in 2005 [1]. PRRS was firstly described in America in 1987 [2], followed in Europe and Asia (1990-1992) [3, 4, 5, 6]. The causative agent, porcine reproductive and respiratory syndrome virus (PRRSV), was isolated in 1991 in the Netherlands and 1992 in the United States with originally isolated strains named Lelystad Virus (the European prototypic strain) and Swine Infertility and Respiratory Syndrome (SIRS) virus (also known as ATCC VR-2332, the North American prototypic strain), respectively [7, 8].

The retrospective studies showed that the conserved serum samples were PRRSV antibody positive as early as 1979 in Canada [9]. PRRSV is an enveloped, single positive-stranded RNA virus. AASV 15/02/17 Emergence of a Novel Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in China. February 15, 2017 — From 2014 to 2015, four novel highly pathogenic PRRS virus (HP-PRRSV) strains named 14LY01-FJ, 14LY02-FJ 15LY01-FJ, and 15LY02-FJ were isolated from high morbidity (100%) and mortality (40%-80%) in piglets and sows in Fujian Province. To further our knowledge about these novel virus strains, we characterized their complete genomes and determined their pathogenicity in piglets. Full-length genome sequencing analysis showed that these four isolates were closely related to type 2 (North American type, NA-type) isolates, with 88.1%-96.3% nucleotide similarity, but only 60.6%-60.8% homology to the Lelystad virus (LV) (European type, EU-type).

The full length of the four isolates was determined to be 15017 or 15018 nucleotides (nt), excluding the poly(A) tail. Furthermore, the four isolates had three discontinuous deletions (aa 322-432, aa 483, and aa 504-522) within hypervariable region II (HV-II) of Nsp2, as compared to the reference strain VR-2332. CDC EID - Volume 16, Number 2–February 2010 - Origin of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus, China. The Veterinary Journal Volume 174, Issue 3, November 2007, Emergence of a highly pathogenic porcine reproductive and respiratory.

Abstract Herds of pigs in the Mid-Eastern region of China have experienced recent outbreaks of a severe form of porcine reproductive and respiratory syndrome (PRRS) characterised by high fever and morbidity and mortality in animals of different ages. Eighty-one herds were diagnosed with PRRS virus (PRRSV) infection from June to December 2006 on the basis of clinical signs, pathological findings and reverse transcriptase polymerase chain reaction (RT-PCR).

Twenty strains of PRRSV were isolated from 20 herds in six provinces. Following experimental inoculation, one isolate, designated SY0608, caused 100% morbidity and 25–50% mortality in 30-, 65- and 105-day-old pigs and the birth of stillborn and weak piglets from affected sows. The ORF5 gene had 99.5–99.8% nucleotide and 99–100% derived amino acid sequence identities among SY0608 and five other field isolates, but only 89.4% and 88.6% identities, respectively, with VR-2332, the prototypic North American isolate. Keywords. PLOS JANVIER 2008 Emergence of Fatal PRRSV Variants: Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection o. Abstract Porcine reproductive and respiratory syndrome (PRRS) is a severe viral disease in pigs, causing great economic losses worldwide each year. The causative agent of the disease, PRRS virus (PRRSV), is a member of the family Arteriviridae. Here we report our investigation of the unparalleled large-scale outbreaks of an originally unknown, but so-called “high fever” disease in China in 2006 with the essence of PRRS, which spread to more than 10 provinces (autonomous cities or regions) and affected over 2,000,000 pigs with about 400,000 fatal cases.

Different from the typical PRRS, numerous adult sows were also infected by the “high fever” disease. Citation: Tian K, Yu X, Zhao T, Feng Y, Cao Z, Wang C, et al. (2007) Emergence of Fatal PRRSV Variants: Unparalleled Outbreaks of Atypical PRRS in China and Molecular Dissection of the Unique Hallmark. Academic Editor: Joel Montgomery, US Naval Medical Research Center Detachment/Centers for Disease Control, United States of America Results.

CDC EID Volume 13, Number 9–September 2007 Highly Pathogenic Porcine Reproductive and Respiratory Syndrome, China. Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed high exposure rates to raccoons, white-tailed deer, and horses. To our knowledge, no laboratory-based assessments of viremic potential of animals infected with HRTV have been performed. We experimentally inoculated several vertebrates (raccoons, goats, chickens, rabbits, hamsters, C57BL/6 mice, and interferon-α/β/γ receptor–deficient [Ag129]) mice with this virus.

All animals showed immune responses against HRTV after primary or secondary exposure. However, neutralizing antibody responses were limited. Only Ag129 mice showed detectable viremia and associated illness and death, which were dose dependent. Archives of Virology (2009) 154:1589-1597, October 08, 2009 Genetic variation and pathogenicity of highly virulent porcine repro. A highly pathogenic swine disease designated as ‘porcine high fever disease (PHFD)’ appeared recently in China. Porcine reproductive and respiratory syndrome virus (PRRSV) was identified as an agent associated with PHFD, and two discontiguous sequence deletions were identified as a genetic marker in the Nsp2 region of the viral genome. To examine PHFD in Shandong province, a total of 10 PRRSV isolates were recovered from pig herds that had never been vaccinated for PRRS.

Sequence analysis of open reading frame 5 (ORF5) showed that the level of identity among the 10 isolates ranged between 88.2 and 99.2%. CRESA - Jornada formativa sobre el control i impacte del PRRS La plataforma per al control del PRRS (ConPRRS) creada recentment i integrada per investigadors del CReSA-UAB, UCM i UdL organitzarà una sessió formativa el proper dijous, 23 de octubre de 201. La plataforma per al control del PRRS (ConPRRS) creada recentment i integrada per investigadors del CReSA-UAB, UCM i UdL organitzarà una sessió formativa el proper dijous, 23 de octubre de 2014, a la Facultat de Veterinària de Saragossa.

Aquesta formació, la primera d'una sèrie de sessions que s'impartiran fins finals de 2014, va dirigida a veterinaris de porcí d'empreses de producció, ADS, així com a funcionaris de l'administració o a qualsevol veterinari o productor interessat en el tema. Les inscripcions han d’estar formalitzades abans del dilluns, 20 octubre de 2014. Per a més informació sobre la inscripció, consulti el programa de la sessió, contacteu-nos per telèfon (+34 93 581 10 47) o per correu (conprrs@cresa.uab.cat).