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Diphtérie à Corynebacterium ulcerans

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CDC EID - OCT 2021 - Widespread Disease in Hedgehogs (Erinaceus europaeus) Caused by Toxigenic Corynebacterium ulcerans (étude belge) An Martel , Filip Boyen, Jörg Rau, Tobias Eisenberg, Andreas Sing, Anja Berger, Koen Chiers, Sarah Van Praet, Serge Verbanck, Muriel Vervaeke, and Frank Pasmans Author affiliations: Ghent University, Merelbeke, Belgium (A.

CDC EID - OCT 2021 - Widespread Disease in Hedgehogs (Erinaceus europaeus) Caused by Toxigenic Corynebacterium ulcerans (étude belge)

Martel, F. Boyen, K. Chiers, S. Hedgehogs across northern Belgium are currently being affected by an ulcerative skin disease. Figure 1 Figure 1. During May and June 2020, we tested 81 hedgehogs (Erinaceus europaeus) that had ulcerative skin lesions and were provided by the public to 4 animal rescue centers across northern Belgium (Figure 1). FRONT. VET. SCI. 01/06/21 Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom.

Background Diphtheria and diphtheria-like infections are caused by three Corynebacterium species, namely, Corynebacterium diphtheriae, Corynebacterium ulcerans, and Corynebacterium pseudotuberculosis.

FRONT. VET. SCI. 01/06/21 Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom

They can all harbor corynephage encoding the tox gene responsible for the production of diphtheria toxin (DT), a potentially lethal exotoxin leading to pseudomembrane formation and to the systemic signs of disease. While C. diphtheriae causes classic human diphtheria and carriage is almost exclusively restricted to people, C. ulcerans and C. pseudotuberculosis are mainly veterinary organisms. FRONT. PUBLIC HEALTH 21/08/19 Whole Genome Sequencing for Surveillance of Diphtheria in Low Incidence Settings. Introduction In recent years, rare but hypervirulent pathogens have been increasingly reported in specific geographic regions (1, 2), often associated with refugees and asylum seekers (3), but also in other high-risk populations including hospitalized patients (4, 5), the elderly, and newborns (6, 7).

FRONT. PUBLIC HEALTH 21/08/19 Whole Genome Sequencing for Surveillance of Diphtheria in Low Incidence Settings

Reports of infections in refugees over the past decade have included Borrelia recurrentis (8), methicillin resistant Staphylococcus aureus (S. aureus) (MRSA) (9, 10), and toxigenic Corynebacterium diphtheriae (11). Médecine et Maladies Infectieuses Volume 49, Issue 4, Supplement, June 2019, Quatorze cas de diphtérie en territoire Guyane française : une émergence à surveiller. Introduction Une épidémie de diphtérie sévit dans plusieurs pays d’Amérique du sud et de la Caraïbe depuis 2014.

Médecine et Maladies Infectieuses Volume 49, Issue 4, Supplement, June 2019, Quatorze cas de diphtérie en territoire Guyane française : une émergence à surveiller

Alors que depuis l’année 2000 la Guyane française n’avait signalé aucun cas de diphtérie, plusieurs cas successifs depuis avril 2016 interpellent. Matériels et méthodes Étude descriptive et rétrospective des cas d’infection à Corynebacterium spp. diagnostiqués en Guyane, ayant fait l’objet d’un signalement au CNR entre le 1er avril 2016 et le 31 janvier 2019.

CLINICAL INFECTIOUS DISEASES 19/08/19 Clinical and Epidemiological Aspects of Diphtheria: A Systematic Review and Pooled Analysis. Emerg Infect Dis. 2019 Oct; Global Epidemiology of Diphtheria, 2000–2017. SCIENTIFIC REPORTS 18/03/21 Molecular and epidemiologic characterization of the diphtheria outbreak in Venezuela. Data collection and study sites Between December 2017 and December 2018 (one of the outbreak peak periods10) nasopharyngeal (NP) or oropharyngeal (OP) swabs from suspected cases were collected at 14 hospitals across the most affected states: 6 hospitals in the Capital District, 2 hospitals in Carabobo, and 1 hospital in each of the following states: Aragua, Bolivar, Mérida, Anzoátegui, Lara and Zulia.

SCIENTIFIC REPORTS 18/03/21 Molecular and epidemiologic characterization of the diphtheria outbreak in Venezuela

Demographic information was retrieved from direct interviews with the patients from whom samples were taken (Tables 1 and 3). In parallel, medical records from cases diagnosed as “Diphtheria”, “suspected Diphtheria”, “Atypical Pharyngotonsilitis” and “Atypical Pharyngitis” were retrospectively reviewed at the study hospitals from June 2016 to July 2019. Relevant demographic data was retrieved when available.

Informed consent was obtained from all subjects or, if subjects were under 18, from a parent and/or legal guardian. Case definitions Laboratory procedures Sequencing and data analysis. CDC EID - MARS 2021 - Addressing Reemergence of Diphtheria among Adolescents through Program Integration in India. Disclaimer: Early release articles are not considered as final versions.

CDC EID - MARS 2021 - Addressing Reemergence of Diphtheria among Adolescents through Program Integration in India

Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: National Centre for Disease Control, New Delhi, India (K.K. SANTE PUBLIQUE FRANCE 01/01/05 La diphtérie en France, 2001- 2003. Surveillance nationale des maladies infectieuses, 2001-2003. CDC EID - MARS 2020 - Diphtheria Outbreaks in Schools in Central Highland Districts, Vietnam, 2015–2018. Disclaimer: Early release articles are not considered as final versions.

CDC EID - MARS 2020 - Diphtheria Outbreaks in Schools in Central Highland Districts, Vietnam, 2015–2018

Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: Nagasaki University, Nagasaki, Japan (N. Kitamura, K. EUROSURVEILLANCE 10/01/19 Whole genome sequencing suggests transmission of Corynebacterium diphtheriae-caused cutaneous diphtheria in two siblings, Germany, 2018 separator commenting unavailable. EUROSURVEILLANCE 27/09/18 Transmission of toxigenic Corynebacterium diphtheriae by a fully immunised resident returning from a visit to West Africa, United Kingdom, 2017.

CDC EID - NOV 2018 - Fatal Case of Diphtheria and Risk for Reemergence, Singapore. Yingqi Lai.

CDC EID - NOV 2018 - Fatal Case of Diphtheria and Risk for Reemergence, Singapore

ROBERT KOCH INSTITUT 22/02/18 Corynebacterium ulcerans – ein Emerging Pathogen? Daten des Konsiliarlabors für Diphtherie 2011 – 2016. Im Epidemiologischen Bulletin 8/2018 werden die Daten des Konsiliarlabors für Diphtherie aus den Jahren 2011-2016 vorgestellt.

ROBERT KOCH INSTITUT 22/02/18 Corynebacterium ulcerans – ein Emerging Pathogen? Daten des Konsiliarlabors für Diphtherie 2011 – 2016

Während in der Prävakzine-Ära und heute noch in Ländern mit inadäquaten Impfquoten hauptsächlich C. diphtheriae für Diphtherie-Erkrankungen verantwortlich war bzw. ist, wird in den letzten Jahren v.a. in Industrienationen zunehmend C. ulcerans als Erreger diphtherieähnlicher Erkrankungen beim Menschen beschrieben. Corynebacterium ulcerans ist im Gegensatz zu C. diphtheriae ein zoonotischer Erreger und wird üblicherweise durch Tierkontakt auf den Menschen übertragen, wobei vermehrt auch bei Haustieren Besiedlungen oder Infektionen mit Übertragung auf den Menschen beobachtet wurden.

INFECTION - OCT 2012 - Rare human skin infection with Corynebacterium ulcerans: transmission by a domestic cat. New Microbes and New Infections Volume 25, September 2018 Genomic analyses reveal two distinct lineages of Corynebacterium ulcerans strains. JavaScript is disabled on your browser.

New Microbes and New Infections Volume 25, September 2018 Genomic analyses reveal two distinct lineages of Corynebacterium ulcerans strains

Please enable JavaScript to use all the features on this page. Abstract Corynebacteriumulcerans is an important zoonotic pathogen which is causing diphtheria-like disease in humans globally. In this study, the genomes of three recently isolated C. ulcerans strains, 4940, 2590 and BR-AD 2649, respectively from an asymptomatic carrier, a patient with pharyngitis and a canine host, were sequenced to investigate their virulence potential. A comparative analysis was performed including the published genome sequences of 16 other C. ulcerans isolates. Infection December 2017, Volume 45, Issue 6 Respiratory diphtheria due to Corynebacterium ulcerans transmitted by a companion dog, Italy 2014.

Journal of medical microbiology - 2012 - Prevalence of Corynebacterium ulcerans in dogs in Osaka, Japan. Rev Saúde Pública 2011;45(6) Corynebacterium ulcerans diphtheria: an emerging zoonosis in Brazil and worldwide. Difteria pelo Corynebacterium ulcerans: uma zoonose emergente no Brasil e no mundo Difteria por Corynebacterium ulcerans: una zoonosis emergente en Brasil y en el mundo Alexandre Alves de Souza de Oliveira DiasI; Louisy Sanchez SantosII; Priscila Soares SabbadiniIII; Cíntia Silva SantosIII; Feliciano Correa Silva JuniorI; Fátima NapoleãoIII; Prescilla Emy NagaoIII; Maria Helena Simões Villas-BôasI; Raphael Hirata JuniorIII; Ana Luíza Mattos GuaraldiIII IDepartamento de Imunologia.

Instituto Nacional de Controle e Controle de Qualidade em Saúde. Fundação Oswaldo Cruz. Correspondência | Correspondence O artigo revisa a literatura sobre a emergência de infecções humanas causadas por Corynebacterium ulcerans em diversos países, incluindo o Brasil. CDC EID - AOUT 2017 - Molecular Characterization of Corynebacterium diphtheriae Outbreak Isolates, South Africa, March–June 2015. Mignon du Plessis. CDC EID - JULY 2017 - Diphtheria in Mayotte, 2007–2015. Emmanuel Belchior1 ( , Sabine Henry1, Edgar Badell, Louis Collet, Thierry Benoit-Cattin, Anne-Marie de Montera, Nicole Guiso, Olivier Patey, Daniel Levy-Bruhl, Laurent Filleul, Francois Chieze, and Sophie Olivier Author affiliations: Santé Publique France, Saint-Maurice, France (E.

PARLEMENT EUROPEEN - Réponse à question E-001983-17 La surveillance et le traitement de la diphtérie dans l'Union européenne.

Diphtérie en Belgique

Diphtérie au Vénézuela. WIKIPEDIA - Diphtheria. Diphtheria is an infection caused by the bacterium Corynebacterium diphtheriae.[1] Signs and symptoms may vary from mild to severe.[2] They usually start two to five days after exposure.[1] Symptoms often come on fairly gradually beginning with a sore throat and fever.[2] In severe cases a grey or white patch develops in the throat.[1][2] This can block the airway and create a barking cough as in croup.[2] The neck may swell in part due to large lymph nodes.[1] A form of diphtheria that involves the skin, eyes, or genitals also exists.[1][2] Complications may include myocarditis, inflammation of nerves, kidney problems, and bleeding problems due to low blood platelets. Myocarditis may result in an abnormal heart rate and inflammation of the nerves may result in paralysis.[1] Diphtheria is usually spread between people by direct contact or through the air.[1][3] It may also be spread by contaminated objects.

Signs and symptoms[edit] A diphtheria skin lesion on the leg Transmission[edit] WIKIPEDIA – Diphtérie. Un article de Wikipédia, l'encyclopédie libre. Int J Contemp Pediatr. 2016; 3(1): 60-63 Resurgence of diphtheria: clinical profile and outcome - a retrospective observational study. Pubmed Style G.V. B, Chebbi PG, Joshi S. Resurgence of diphtheria: clinical profile and outcome - a retrospective observational study. Int J Contemp Pediatr. 2016; 3(1): 60-63. doi:10.18203/2349-3291.ijcp20160058 Web Style G.V. AMA (American Medical Association) Style G.V. PLOS 24/04/15 Diphtheria in Lao PDR: Insufficient Coverage or Ineffective Vaccine? Abstract Background During late 2012 and early 2013 several outbreaks of diphthe-ria were notified in the North of the Lao People’s Democratic Republic.

The aim of this study was to determine whether the re-emergence of this vaccine-preventable disease was due to insufficient vaccination coverage or reduction of vaccine effectiveness within the affected regions. CLINICAL MICROBIOLOGY AND INFECTION - OCT 2006 - Susceptibility to diphtheria in adults: prevalence and relationship to gender and social variables. CrossrefSee all References13], but included both children and adults, while the present study included only adults. In general, this north-eastern region of Germany has a high infant vaccine coverage of nearly 100%. Upon comparison of the results of the two studies within the specific age strata, the susceptibility proportions were almost identical. PubMedSee all References23], individuals aged ≥ 70 years had a relatively low degree of seroprotection in the present study.

Abstract | Full Text | Full Text PDF | PubMed | Scopus (14)See all References25]. Crossref | PubMed | Scopus (82)See all References]. INTERNATIONAL JOURNAL OF INFECTIOUSDISEASES - FEV 2014 - Diphtheria in Andhra Pradesh–a clinical-epidemiological study. See all References7 It was clearly observed in the present study that clinical diphtheria in non-immunized CD-positive patients presented differently from that in immunized COD-positive patients.

Among non-immunized patients, features such as lymphadenitis, stridor, myocarditis, soft tissue swelling, and pneumonitis were either present at the time of admission or developed within 1–2 days of the hospital stay. CD was isolated predominantly from these patients. PubMedSee all References leading to tissue damage, non-immunized and CD-positive patients developed complications associated with diphtheria (Table 1Table 1). See all References Studies carried out at different places in our country have reported that diphtheria occurs more frequently during the months from September to November. PubMedSee all References15 reported a similar low microbiological confirmation rate for clinical diphtheria. PubMedSee all References17 See all References7. PLOS 10/02/16 Long-Term Protection against Diphtheria in the Netherlands after 50 Years of Vaccination: Results from a Seroepidemiological Study.

Abstract Background and Aims To evaluate the National Immunisation Programme (NIP) a population-based cross-sectional seroepidemiological study was performed in the Netherlands. ECDC 30/07/15 Cutaneous diphtheria among recently arrived refugees and asylum seekers in the EU. PUBLIC HEALTH ENGLAND - MARS 2015 - Public health control and management of diphtheria (in England and Wales) - 2015 Guidelines. ECDC 31/07/15 Cutaneous diphtheria among recently arrived refugees and asylum-seekers in the EU. A total of nine cases of cutaneous diphtheria among refugees and asylum-seekers have been notified by Denmark, Sweden and Germany in 2015. According to ECDC's rapid risk assessment, there is no indication that these cases represent a significant outbreak of diphtheria among refugees in Europe. However, health systems might not be able to detect cutaneous diphtheria outbreaks among refugees because refugees have limited access to health services.

Travellers to diphtheria-endemic countries should check their vaccination status before departure and get a booster dose if their last diphtheria vaccination was more than 10 years ago. Refugees who lack evidence of vaccination against diphtheria should be considered as unprotected and be provided with the appropriate vaccination in accordance with national immunisation guidelines. European travellers may get infected and develop a cutaneous diphtheria while travelling or working in endemic countries. Related links: ISP WIV (BE) - 2014 - Diphtérie. DAILY TIMES (PK) 27/11/16 Around 398 cases of diphtheria, 9,000 cases of measles reported in KP, FATA. PESHAWAR: Around 398 cases of Diphtheria disease were registered while more than 9,000 cases of measles were reported in Khyber Pakhtunkhwa (KP) this year.

According to Khyber Pakhtunkhwa Health Department 398 cases of diphtheria disease were reported from KP and Federal Administered Tribal Areas (FATA) this year. The report further said that more than 70 per cent cases were reported from Bannu, while the second on the top list was North and South Waziristan where more cases of diphtheria were reported, adding that other districts of the province were also receive cases as well. An official of the health department on the condition of anonymity said that because of the poor vaccination the diphtheria cases were increased in the province. He further added that in the country vaccination campaign has started since 1998 but still in KP and FATA like measles, diphtheria and polio disease were still in the province which shows that the performance of district vaccinators is poor.

ECDC 15/06/15 A case of diphtheria in Spain. AFP 27/06/15 Espagne: disparue depuis 1987, la diphtérie tue un enfant de six ans non-vacciné. La vaccination fait aussi polémique chez nos voisins. En Espagne, un enfant de six ans est décédé de la diphtérie après un mois de lutte contre la bactérie, alors que le dernier cas remontait à 1987, a annoncé ce samedi l'hôpital qui le soignait. L'enfant n'étant pas vacciné, son cas a fait débat, comme récemment en France ou encore au Canada.

C'est sur son compte Twitter que l'hôpital de Vall d'Hebron, situé à Barcelone, dans l'est du pays, a confirmé "la mort du patient affecté par la diphtérie", qui était hospitalisé depuis fin mai. LE MONDE PLANETE 10/06/15 Trente ans après son éradication, la diphtérie réapparaît en Espagne. Le cas d’un enfant de six ans non vacciné et dans un état critique après avoir contracté la maladie suscite une vive polémique. EUROSURVEILLANCE 05/06/14 Au sommaire: Emergence and molecular characterisation of non-toxigenic tox gene-bearing Corynebacterium diphtheriae biovar mitis in the United Kingdom, 2003–2012.

Non-toxigenic Corynebacterium diphtheriae have become increasingly recognised as emerging pathogens across Europe causing severe invasive disease. A subset of non-toxigenic C. diphtheriae are ‘non-toxigenic tox gene-bearing’ (NTTB) strains; these strains are genotypically toxpositive, but do not express the protein. The circulation of NTTB strains was first observed during the 1990s upsurge of diphtheria in Eastern Europe but has not been reported in other European countries. Circulation of NTTB strains could be considered an increased risk for diphtheria and other related diseases, given their possible role as a tox gene reservoir with the theoretical risk of re-emerging toxin expression. REUTERS 23/11/16 Animal-rights groups fund diphtheria study to advance medicine, spare horses.

EUROSURVEILLANCE 01/12/16 More than 20 years after re-emerging in the 1990s, diphtheria remains a public health problem in Latvia. Cutaneous diphtheria among recently arrived... ECDC 15/06/15 Diphtheria case highlights shortage of antitoxin in EU. SCIENCES ET AVENIR 04/06/15 ALERTE. 1er cas de diphtérie en Espagne 28 ans après l'éradication. Zoonotic Transmission of Toxigenic Corynebacterium ulcerans Strain, Germany, 2012 - Volume 21, Number 2—February 2015. CDC EID - AOUT 2009 - Pigs as a source for toxigenic Corynebacterium ulcerans. CDC EID - JUIN 2003 - Corynebacterium ulcerans Diphtheria in Japan. EUROSURVEILLANCE - AOUT 2010 - Toxigenic Corynebacterium ulcerans infection in a veterinary student in London, United Kingdom, M. CDC EID - SEPT 2011 - Toxigenic Corynebacterium ulcerans in Woman and Cat.