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COVID-19 et réponse immunitaire

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FRANCE TV 05/02/21 TELEMATIN - L'application « NUTRICovid » répond aux questions que les Français se posent et aident à allier nutrition et immunité. CURRENT RESEARCH IN NUTRITION AND FOOD SCIENCE 04/02/21 Impact of Different Dietary Patterns and Micronutrients on the Immune System and COVID-19 Infection. Introduction During the global pandemic of coronavirus disease-19 (COVID-19), many people have sought to improve their health by eating a healthier diet.

CURRENT RESEARCH IN NUTRITION AND FOOD SCIENCE 04/02/21 Impact of Different Dietary Patterns and Micronutrients on the Immune System and COVID-19 Infection

The World Health Organization (WHO) released guidelines for healthy eating during the lockdown period.1 Despite the fact that there is no specific food or dietary pattern that can prevent the infection with COVID-19, it has been a well-established impact of nutrition on immune system developments and responses.1 Dietary intake has a central role in shipping the gut microbiome, which is the main factor influencing immune cells’ development and immune responses.2,3 Nutrition or dietary factors can be described as a single or a whole diet.

A single diet such as protein, vitamin D, mineral iron, or a bioactive substance such as polyphenols. FRANCE 2 02/02/21 Covid-19 : les habitants de New Delhi ont-ils développé une immunité collective ? FRONT. VET. SCI. 08/01/21 The Strategy of Boosting the Immune System Under the COVID-19 Pandemic. Introduction Coronaviridae is one of the families of viruses that are known to cause diseases in birds and mammals ranging from the common cold to severe acute respiratory syndrome (SRAS).

FRONT. VET. SCI. 08/01/21 The Strategy of Boosting the Immune System Under the COVID-19 Pandemic

A new species that belongs to this family emerged in late 2019, causing an outbreak of a respiratory disease in the eastern part of Asia. The first species of coronavirus infecting humans (229E) was observed in 1931 and isolated first in 1965. Ultimately, the virus has evolved into the novel coronavirus (2019-n-CoV). Regarding the current situation of the COVID-19 pandemic, in which there is no optimal vaccination or cure, the functionality and efficiency of the immune response is the key factor in the defense against viral infections. In the literature, several micronutrients, herbal therapeutics, and probiotics were reported to have positive effects in both treatment and prophylaxis of viral infections (5).

LAB WORLDWIDE 13/11/20 UK: Covid-19 under the Microscope - Dissecting the Immune Characteristics of Severe Covid-19 Responses. 16.11.2020Editor: Alexander Stark Researchers have analysed immune cell types and numbers from the blood of healthy volunteers, Covid-19 patients experiencing mild-to-moderate effects and patients classified as severe.

LAB WORLDWIDE 13/11/20 UK: Covid-19 under the Microscope - Dissecting the Immune Characteristics of Severe Covid-19 Responses

After comparing the T cell immune response, the researchers noted the surprising absence of a strong anti-viral response in the blood of Covid-19 patients. NATURE 21/10/20 The false promise of herd immunity for COVID-19. In May, the Brazilian city of Manaus was devastated by a large outbreak of COVID-19.

NATURE 21/10/20 The false promise of herd immunity for COVID-19

Hospitals were overwhelmed and the city was digging new grave sites in the surrounding forest. But by August, something had shifted. Despite relaxing social-distancing requirements in early June, the city of 2 million people had reduced its number of excess deaths from around 120 per day to nearly zero. In September, two groups of researchers posted preprints suggesting that Manaus’s late-summer slowdown in COVID-19 cases had happened, at least in part, because a large proportion of the community’s population had already been exposed to the virus and was now immune.

Immunologist Ester Sabino at the University of São Paulo, Brazil, and her colleagues tested more than 6,000 samples from blood banks in Manaus for antibodies to SARS-CoV-2. “We show that the number of people who got infected was really high — reaching 66% by the end of the first wave,” Sabino says. What is herd immunity? How do you achieve it? FAPESP_BR 14/10/20 Immunity induced by other coronaviruses may not protect older people against COVID-19. Study led by researchers at Oxford University suggests that after successive infections by the coronaviruses that cause common colds throughout life the defense system becomes specialized and cannot recognize emergent varieties such as SARS-CoV-2 (image: Wikimedia Commons) October 14, 2020 By André Julião | Agência FAPESP – An international research group led by scientists at the University of Oxford in the United Kingdom have developed a mathematical model that may explain why children are less susceptible to COVID-19 while older people frequently become critically ill when infected by the novel coronavirus.

FAPESP_BR 14/10/20 Immunity induced by other coronaviruses may not protect older people against COVID-19

The researchers correlated the age of infected subjects with the severity of symptoms in cases documented in Europe, concluding that exposure in childhood to other endemic human coronaviruses (eHCoVs), which mostly cause only common colds or similarly mild respiratory symptoms, triggers an immune response that may also protect the organism against the novel coronavirus. Republish. FRANCE CULTURE 25/09/20 LE DIRECT - Covid-19 : des réponses immunitaires différentes chez les enfants / L'effet placebo et son explication biologique. HEIDI 14/09/20 Immunité collective: où en est-on? La réponse de deux épidémiologistes français. Où en est-on de l’immunité collective contre le coronavirus?

HEIDI 14/09/20 Immunité collective: où en est-on? La réponse de deux épidémiologistes français

Dans un commentaire paru le 9 septembre dans la revue Nature, le Pr Arnaud Fontanet et son collègue Simon Cauchemez, spécialistes des maladies émergentes à l’institut Pasteur, dressent un bilan d’étape. Les deux épidémiologistes, membres du conseil scientifique français sur Covid-19, estiment qu’un effet protecteur global ne pourra être obtenu que lorsque 50% au moins de la population aura été immunisée contre le virus. On en est encore loin, puisque seulement 10% à 15% de la population des pays européens possède des anticorps contre Covid-19. Autrement dit, l’immunité collective est encore un horizon lointain, qui ne pourra être atteint qu’au prix d’une large circulation virale ou de campagnes de vaccination ambitieuses.

Le concept d’immunité collective. FRONT. VET. SCI. 24/08/20 The strategy of boosting the immune system under CoViD-19 pandemic. 1Department of Poultry, Faculty of Agriculture, Zagazig University, Egypt 2Department of Arid Land Agriculture, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Saudi Arabia 3Forensics Medicine and toxicology Department, Faculty of Veterinary Medicine, Zagazig University, Egypt 4Department of Poultry Production, Faculty of Agriculture, Fayoum University, Egypt 5Department of Biological Science, Faculty of Sciences, King Abdulaziz University, Saudi Arabia 6Department of Pathology, Faculty of Veterinary Medicine, Alexandria University, Egypt 7Faculty of Veterinary Medicine, University of Sarajevo, Bosnia and Herzegovina 8Department of Fish and Animal Production, King Faisal University, Saudi Arabia.

FRONT. VET. SCI. 24/08/20 The strategy of boosting the immune system under CoViD-19 pandemic

KAROLINSKA INSTITUTET (SE) 18/08/20 Immunity to COVID-19 is probably higher than tests have shown. Inspq_qc_ca - 2020 - Survol des recommandations en matière d’alimentation pour les personnes aînées en contexte de pandémie de COVID-19. CDC EID - SEPT 2020 - Antibody Responses after Classroom Exposure to Teacher with Coronavirus Disease, March 2020. Disclaimer: Early release articles are not considered as final versions.

CDC EID - SEPT 2020 - Antibody Responses after Classroom Exposure to Teacher with Coronavirus Disease, March 2020

Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N.E. Brown, J. Bryant-Genevier, M. Dott, S.N. In late February 2020, a teacher experienced headache, sore throat, myalgia, and fatigue while traveling in Europe, where community transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was ongoing (1).

During February 24–27, the teacher taught 16 classes, all in the same room, each with <30 students. Median participant age was 17 years (range 5–18 years). Participating students completed a questionnaire about symptoms experienced during the quarantine period and provided a blood specimen. AFP 23/06/20 CORONAVIRUS : LES ANTICORPS EN FORTE BAISSE DEUX MOIS APRÈS L’INFECTION CHEZ LES PERSONNES GUÉRIES. D’après une étude chinoise, les personnes qui ont été infectées par le nouveau coronavirus voient leurs anticorps fortement baisser deux mois après leur guérison.

AFP 23/06/20 CORONAVIRUS : LES ANTICORPS EN FORTE BAISSE DEUX MOIS APRÈS L’INFECTION CHEZ LES PERSONNES GUÉRIES

Dans cette enquête, publiée jeudi dans Nature Medicine, les chercheurs avertissent des risques d'instituer des «passeports d'immunité» qui seraient censés assurer que leurs détenteurs sont protégés contre la maladie. L'étude décrit sur le plan immunologique et clinique, le cas de 37 personnes sans symptômes dont l'infection a été diagnostiquée par un test virologique (RT-PCR par prélèvement naso-pharyngé) dans le district de Wanzhou (sud-ouest de la Chine) avant le 10 avril dernier. Parmi ces 37 patients asymptomatiques, 22 étaient des femmes et 15 des hommes, âgés de 8 à 75 ans. Huit semaines après la sortie de l'hôpital, les niveaux d'anticorps neutralisants, qui confèrent a priori une immunité contre le virus, avaient diminué chez 81,1% des patients sans symptômes, contre 62,2% chez les patients symptomatiques.

CDC EID - SEPT 2020 - Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and Immunity. Disclaimer: Early release articles are not considered as final versions.

CDC EID - SEPT 2020 - Seroepidemiologic Study Designs for Determining SARS-COV-2 Transmission and Immunity

Any changes will be reflected in the online version in the month the article is officially released. Author affiliations: National University of Singapore Saw Swee Hock School of Public Health, Singapore (H. Clapham, C.C. Tam); Harvard University T.H. Chan School of Public Health, Boston, Massachusetts, USA (J. Serologic studies are crucial for understanding current and future dynamics of the coronavirus disease (COVID-19) pandemic.

Figure 1 Figure 1. INSERM 15/06/20 Comprendre la réponse immunitaire mémoire après le Covid-19. Les lymphocytes mémoires B et T CD4 sont spécifiques d’un virus et sont réactivés en cas de rencontre ultérieure avec ce même virus. Les cellules T CD4 mémoires aident à la réactivation des cellules B mémoires qui se différencient alors en cellules productrices d’anticorps dirigés contre le virus (plasmocytes). UK RESEARCH 11/05/20 UK Researchers Will Lead Study of COVID-19 Immunity. RTBF 17/03/20 Coronavirus: la Grande-Bretagne choisit la stratégie de l'immunité collective. C'est quoi ? C'est efficace ? Coronavirus : Boris Johnson choisit la stratégie de l'immunité collective contre le COVID-19 - © KURT DESPLENTER - BELGA En Grande-Bretagne, pas de confinement.

Le pays a opté pour la stratégie "de l’immunité collective". On l’appelle aussi "immunité de communauté" ou "immunité grégaire". Cette stratégie part d’un principe : la propagation d’une maladie contagieuse peut être enrayée si une proportion importante de la population développe une immunité face à la maladie. OMS VIA YOUTUBE 23/04/20 Q&A on immunization. LE PARISIEN 26/03/20 Coronavirus : Pays-Bas, Suède, Royaume-Uni… La théorie de «l’immunité collective» mise à mal. LE MONDE 27/05/20 Le SARS-CoV-2 entraîne bien une immunité protectrice. Parmi les multiples questions qui restent posées à propos du Covid-19, celle de la réponse immunitaire et de la protection qu’elle pourrait conférer aux personnes ayant été infectées n’est pas la moindre.

LE FIGARO 23/01/20 Coronavirus: «L’espèce humaine n’a aucune immunité» Immunity. 2020 May 3. SARS-CoV-2: Combating Coronavirus Emergence. FRANCE INFO 23/03/20 Coronavirus : les Pays-Bas font le pari de l’immunité collective. FRANCE INFO 12/02/20 Coronavirus Covid-19 : "C'est notre propre système immunitaire qui fait partir le virus", explique un chercheur de l'institut Pasteur. FRANCE 3 26/05/20 Coronavirus : une étude de l’institut Pasteur démontre une possible immunité. EUREKALERT 12/05/20 Passive immunization may slow down SARS-CoV-2 and boost immunity in patients, buying time.

Amsterdam, May 12, 2020 - The worldwide COVID-19 pandemic has infected more than 4 million people and killed close to 280,000.1 Finding a vaccine has become a global public health priority. However, creating a viable vaccine might take a long time; scientists estimate a vaccine may be available in between 12 and 18 months. A potential interim solution reported in the International Journal of Risk & Safety in Medicine may be a passive vaccine, or passive immummization (PI), which can provide instant, short-term fortification against infectious agents. "Using valuable plasma from recovered patients might be useful in our global war against COVID-19," explained Foad Alzoughool, PhD.

After exposure to a viral infection, an individual's body creates antibodies to fight off the virus. The use of PI immunization dates to the beginning of the twentieth century during the Spanish flu epidemic, when patients who received convalescent plasma serum had lower mortality rates than others. ANSES 14/04/20 AVIS de l'Anses relatif à l'évaluation des risques liés à la consommation de compléments alimentaires contenant des plantes pouvant interférer avec la réponse immunitaire et inflammatoire associée à l'infection par le SARS-Cov-2.