Antimicrobial Resistance & Infection Control 23/02/18 Superbugs in the supermarket? Assessing the rate of contamination with third-generation cephalosporin-resistant gram-negative bacteria in fresh Australian pork and chicken. This study of Australian chicken and pork is notable for a number of reasons.
Firstly, we assessed for a broad range of Gram-negative organisms, not simply the traditional species of E. coli or Salmonella spp. [6, 8, 9, 10]. Taking this approach, we identified that 93% of specimens appeared to be contaminated with a wide variety of 3GCR species, including particularly Acinetobacter baumannii complex, Pseudomonas aeruginosa, Serratia fonticola and Hafnia alvei. We were surprised by the relatively high rates of these potential pathogens and initially speculated that perhaps they were due to a point-source within certain supermarkets or butcher shops, such as has been reported in one outbreak of multidrug-resistant K. pneumoniae .
Occurrence of CR E. coli was extremely variable among farms. Pigs were more likely to be positive at slaughter if they were positive as piglets. Shedding of CR E. coli increased with the treatment and decreased with the age. CRESA_CAT 17/08/16 The use of antibiotics in pig farms may endanger public health? Study of the emergence of resistance. One of the negative consequences of the extensive use of antimicrobials in human and veterinary medicine is the appearance of bacteria resistant to antimicrobials.
In those cases of severe infections, or when the patient suffers immune depression, the presence of antimicrobial resistant bacteria can increase the morbidity or mortality of the patient. For this reason, the World Health Organization (WHO) has classified some antimicrobial drugs as critically important in human medicine, since they are the last option to treat some infectious diseases. Third generation cephalosporin and macrolides are some of these antimicrobials. Additionally, the majority of the antimicrobials used in veterinary medicine are structurally similar to those used to treat human infections. IRTA 10/06/15 Transitory emergence of cephalosporin resistant E. coli is associated with beta-lactams treatments in pigs. A recently published study describes that the treatment of pigs with ceftiofur and amoxicillin are associated with the emergence of cephalosporin resistant (CR) E. coli during the course of the treatment.
This collaborative study was carried out by researchers of CReSA (IRTA-UAB), Universidad Complutense de Madrid and Universitat de Lleida. Dr. Migura, researcher of CReSA, briefly explains: “The study showed that both treatments generate an increase in the prevalence of CR E. coli during the treatment period, but resistance diminished after treatment and by the time of finishing, CR E. coli bacteria was not recovered from the animals”. The study was designed as follows. One hundred 7-day-old piglets were divided into two groups, a control group and a group parenterally treated with ceftiofur.
PIG PROGRESS 12/08/11 Cephalosporin antibiotics: Control or ban? The Panel of Biological Hazards (BIOHAZ) of EFSA has just published an opinion on the public health risks of bacterial strains (primarily E. coli and Salmonella species) producing extended-spectrum beta-lactamase (ESBL) enzymes or AmpC beta lactamases in food producing animals and food.
These enzymes cause resistance to 3rd and 4th generation cephalosporins, such as ceftiofur and cefquinome and are thought to be associated with their use in veterinary medicine. Research in Veterinary Science - FEV 2010 - Resistance mechanisms and farm-level distribution of fecal Escherichia coli isolates. Abstract Introduction.
Foodborne Pathog Dis. 2011 Aug 5. Ceftiofur Use in Finishing Swine Barns and the Recovery of Fecal Escherichia coli or Salmonell. ALLIANCE PORCI D'OC 28/04/11 Antibiorésistance: moratoire sur les Céphalosporines en élevages de porcs. Mardi 26 avril 2011 2 26 / 04 / Avr / 2011 18:12 Les représentants de la filière porcine (Coop de France, FNP, INAPORC) ont décidé la mise en oeuvre d'un moratoire (suspension volontaire et provisoire de l'utilisation d'un produit vétérinaire) sur l'utilisation des antibiotiques de type céphalosporine de 3è et 4è génération (C3-4G : ceftiofur, cefquinome) en élevage de porcs.
Ce moratoire s'appliquera à compter du 1er mai 2011 pour une durée de 2 ans. La mise en place de ce dispositif s'appuiera notamment sur le suivi de l'évolution des consommations des céphalosporines et des pratiques d'élevage. Ces actions seront conduites en partenariat et en totale harmonie avec les organisations vétérinaires (AVPO, AFMVP, SNGTV).