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Journal of Applied Ecology 07/11/16 Challenging the conceptual framework of maintenance hosts for influenza A viruses in wild birds. THE LANCET 19/05/17 Stopping emerging influenza viruses at their origin. During the past 100 years, two of four influenza virus pandemics originated in Asia.

THE LANCET 19/05/17 Stopping emerging influenza viruses at their origin

Additionally, many of the emerging influenza viruses that are deemed to have pandemic potential, including H5N1, H5N6, H6N1, H7N9, and H10N8, have crossed the species barrier from animals to human beings in Asia.1, 2, 3, 4, 5, 6 One reason for this might be the extensive interface between human beings, domestic poultry, and wild waterfowl, which is generated by the high human population density, the high density of domestic poultry, and ample opportunities for domestic birds to be exposed to wild waterfowl in some regions of Asia.

This environment provides avian influenza viruses with the opportunity to evolve, reassort, and, ultimately, infect human beings. Although zoonotic infections might have high case-fatality rates, it is unlikely that a fully avian virus will cause the next pandemic. Efforts to create vaccines against avian influenza viruses of concern have mainly focused on H5 and H7 viruses. VIRUS EVOLUTION 18/03/17 Adaptation of avian influenza virus to a swine host. Skip to Main Content Sign In Register Advanced Search Online ISSN 2057-1577 Print ISSN Copyright © 2017 Oxford University Press Connect Resources Explore.

VIRUS EVOLUTION 18/03/17 Adaptation of avian influenza virus to a swine host

PLOS 09/03/17 Discordant detection of avian influenza virus subtypes in time and space between poultry and wild birds; Towards improvement of surveillance programs. Abstract Avian influenza viruses from wild birds can cause outbreaks in poultry, and occasionally infect humans upon exposure to infected poultry.

PLOS 09/03/17 Discordant detection of avian influenza virus subtypes in time and space between poultry and wild birds; Towards improvement of surveillance programs

Identification and characterization of viral reservoirs and transmission routes is important to develop strategies that prevent infection of poultry, and subsequently virus transmission between poultry holdings and to humans. Int. J. Environ. Res. Public Health 2017, 14(3), 263; Comparative Epidemiology of Human Fatal Infections with Novel, High (H5N6 and H5N1) and Low (H7N9 and H9N2) Pathogenicity Avian Influenza A Viruses. This study aimed to assess the mortality risks for human infection with high (HPAI) and low (LPAI) pathogenicity avian influenza viruses.

Int. J. Environ. Res. Public Health 2017, 14(3), 263; Comparative Epidemiology of Human Fatal Infections with Novel, High (H5N6 and H5N1) and Low (H7N9 and H9N2) Pathogenicity Avian Influenza A Viruses

The HPAI case fatality rate (CFR) was far higher than the LPAI CFR [66.0% (293/444) vs. 68.75% (11/16) vs. 40.4% (265/656) vs. 0.0% (0/18) in the cases with H5N1, H5N6, H7N9, and H9N2 viruses, respectively; p < 0.001]. Similarly, the CFR of the index cases was greater than the secondary cases with H5N1 [100% (43/43) vs. 43.3% (42/97), p < 0.001]. Old age [22.5 vs. 17 years for H5N1, p = 0.018; 61 vs. 49 years for H7H9, p < 0.001], concurrent diseases [18.8% (15/80) vs. 8.33% (9/108) for H5N1, p = 0.046; 58.6% (156/266) vs. 34.8% (135/388) for H7H9, p < 0.001], delayed confirmation [13 vs. 6 days for H5N1, p < 0.001; 10 vs. 8 days for H7N9, p = 0.011] in the fatalities and survivors, were risk factors for deaths. CDC EID - FEV 2017 - Au sommaire notamment: Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity. Hongbo Guo1, Erik de Vries1, Ryan McBride, Jojanneke Dekkers, Wenjie Peng, Kim M.

CDC EID - FEV 2017 - Au sommaire notamment: Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity

Bouwman, Corwin Nycholat, M. Helene Verheije, James C. Paulson, Frank J.M. van Kuppeveld, and Cornelis A.M. de Haan ( Author affiliations: Utrecht University, Utrecht, the Netherlands (H. Highlight and copy the desired format. Abstract. CDC EID - MARS 2005 - Rumor Surveillance and Avian Influenza H5N1. CDC EID - FEV 2017 - H5Nx Panzootic Bird Flu—Influenza’s Newest Worldwide Evolutionary Tour. Author affiliations: National Institutes of Health, Bethesda, Maryland, USA (J.K.

CDC EID - FEV 2017 - H5Nx Panzootic Bird Flu—Influenza’s Newest Worldwide Evolutionary Tour

Taubenberger, D.M. Morens); Associate Editor, Emerging Infectious Diseases, Atlanta, Georgia, USA (D.M. Morens) Suggested citation for this article. PLOS 23/11/16 Avian Influenza Risk Surveillance in North America with Online Media. Abstract The use of Internet-based sources of information for health surveillance applications has increased in recent years, as a greater share of social and media activity happens through online channels.

PLOS 23/11/16 Avian Influenza Risk Surveillance in North America with Online Media

The potential surveillance value in online sources of information about emergent health events include early warning, situational awareness, risk perception and evaluation of health messaging among others. The challenge in harnessing these sources of data is the vast number of potential sources to monitor and developing the tools to translate dynamic unstructured content into actionable information. In this paper we investigated the use of one social media outlet, Twitter, for surveillance of avian influenza risk in North America. We collected AI-related messages over a five-month period and compared these to official surveillance records of AI outbreaks. Citation: Robertson C, Yee L (2016) Avian Influenza Risk Surveillance in North America with Online Media.

Infectious Diseases of Poverty (2015) 4:50 Prediction of the next highly pathogenic avian influenza pandemic that can cause illness in humans. During the past decade, an endless stream of avian influenza viruses (AIVs), including H1N1, H5N1, and H7N9, has emerged, leading to humans developing malignant respiratory diseases.

Infectious Diseases of Poverty (2015) 4:50 Prediction of the next highly pathogenic avian influenza pandemic that can cause illness in humans

The variation trend of influenza viruses needs to be urgently studied. In 1918, the Spanish flu, which was later confirmed as the H1N1 influenza virus, caused at least 20 million deaths worldwide (incomplete statistic) [1, 2]. Why was the Spanish flu so dangerous, and is there a possibility that there could be another outbreak like this in the future?

These questions cannot be sufficiently answered using the current studies. In this paper, we attempt to answer these questions using new bioinformatic systems. INFECTION ECOLOGY & EPIDEMIOLOGY 08/09/15 Mallard or chicken? Comparing the isolation of avian influenza A viruses in embryonated Mallard and chicken eggs. Infection Ecology and Epidemiology 11/10/16 Risk of resistant avian influenza A virus in wild waterfowl as a result of environmental release of oseltamivir. Anna Gillman, MD, PhD1,2* 1Section for Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden; 2Zoonosis Science Centre, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden Oseltamivir is the best available anti-influenza drug and has therefore been stockpiled worldwide in large quantities as part of influenza pandemic preparedness planning.

Infection Ecology and Epidemiology 11/10/16 Risk of resistant avian influenza A virus in wild waterfowl as a result of environmental release of oseltamivir

The active metabolite oseltamivir carboxylate (OC) is stable and is not removed by conventional sewage treatment. Active OC has been detected in river water at concentrations up to 0.86 µg/L. Although the natural reservoir hosts of influenza A virus (IAV) are wild waterfowl that reside in aquatic environments, the ecologic risks associated with environmental OC release and its potential to generate resistant viral variants among wild birds has largely been unknown.

PLOS 13/10/16 Persistence of Low Pathogenic Influenza A Virus in Water: A Systematic Review and Quantitative Meta-Analysis. Abstract Avian influenza viruses are able to persist in the environment, in-between the transmission of the virus among its natural hosts.

PLOS 13/10/16 Persistence of Low Pathogenic Influenza A Virus in Water: A Systematic Review and Quantitative Meta-Analysis

Quantifying the environmental factors that affect the persistence of avian influenza virus is important for influencing our ability to predict future outbreaks and target surveillance and control methods. Tierarztl Prax Ausg G Grosstiere Nutztiere. 2016;44(1):26-33. [Role of the poultry red mite (Dermanyssus gallinae) in the transmission of avian influenza A virus]. JOURNAL OF MEDICAL VIROLOGY - 2013 - Susceptibility of Human and Avian Influenza Viruses to Human and Chicken Saliva. AGENCY FOR SCIENCE SINGAPORE 29/05/12 Made-In-Singapore H5N1 Bird Flu Diagnostic Kit – Detects All Known Strains of H5N1 Virus With A Single Test. Applied Biosafety Vol. 16, No. 1, 2011 Effect of Drying and Exposure to Vaporous Hydrogen Peroxide on the Inactivation of Highly Pathogenic Avian Influenza (H5N1) on Non-porous Surfaces.

This study demonstrated the combined effect of drying and vaporous hydrogen peroxide exposure on inactivating highly pathogenic avian influenza (H5N1) on the non-porous materials glass, Hypalon® rubber glove, and stainless steel. Approximately 7.7 log10 TCID50 (median 50% tissue culture infectious dose)/mL of A/Vietnam/1203/2004 H5N1 in allantoic fluid was dried on coupons of each type of test surface and exposed to vaporous hydrogen peroxide fumigation within a ∼15 m3 chamber.

A significant reduction in the total log10 TCID50 of H5N1 on all test materials was observed between the controls evaluated after a 1-hour drying time and unexposed controls evaluated after decontamination. The H5N1 exhibited a 2–3 log decrease in viability, and vaporous hydrogen peroxide further inactivated the virus to below detectable levels. In parallel Geobacillus stearothermophilus biological indicators exposed to vaporous hydrogen peroxide exhibited no growth after 1 and 7 days' incubation. Veterinary Science - 2012 - Study of Maternal Antibody’s Neutralization Ability for Anti AI H5 in Chicken’s Egg Yolk Induce From Several Commercial Vaccines Against Field of AI H5N1 Virus. Critical Reviews in Microbiology Volume 41, Issue 4, 2015 Laridae: A neglected reservoir that could play a major role in avian influenza virus epidemiological dynamics. WebImagesPlus… EU-SPRI CONFERENCE - 2014 - Avian influenza narratives and research landscapes: towards new science policy approaches in biomedicine.

FRONTIERS IN MICROBIOLOGY 24/06/16 Pathogenesis and phylogenetic analyses of two avian influenza H7N1 viruses isolated from wild birds. Hongmei Jin1, Deli Wang3, Jing Sun1, 4, Yanfang Cui3, Guang Chen1, 5, Xiaolin Zhang1, Jiajie Zhang1, Xiang Li1, Hongliang Chai1*, Yuwei Gao2*, Yanbing Li3* and Yuping Hua1* FRONTIERS IN VETERINARY SCIENCE 23/05/16 Commentary: Differences in the Epidemiology of Human Cases of Avian Influenza A (H7N9) and A (H5N1) Viruses Infection.

1Jilin university, China A commentary onDifferences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection by Qin et al. Clin Infect Dis (2015) 61:563–71. doi: 10.1093/cid/civ345. Clinical Infectious Diseases 04/05/15 Differences in the epidemiology of human cases of avian influenza A(H7N9) and A(H5N1) viruses infection. International Congress Series 1263 (2004) 114–117 Molecular determinants of the pathogenicity of H5N1 influenza viruses in chickens. Int. J. Livest. Res.. 2013; 3(4): 5-13 Avian Influenza - The Eminent Pandemic Threat. Pubmed Style wani N, Munshi Z, mir i, tramboo s. Avian Influenza - The Eminent Pandemic Threat. Int. J. Livest.

Références universitaires

VETERINARY RESEARCH - 2014 - The NS segment of H5N1 avian influenza viruses (AIV) enhances the virulence of an H7N1 AIV in chickens. The pathogenic potential of some strains of IAV has been related to multiple factors, including viral determinants and an excessive host immune response [32–41]. Since most of these descriptions have been done in mammals, in the present study we tried to extend these studies to natural hosts of AIV. More specifically, we focused our studies on the understanding of the role that the AIV NS-segment of two different H5- HPAIV strains plays during pathogenesis in birds.

To this end, an experimental infection in SPF-chickens was designed with an H7N1 HPAIV (FPV) and two reassortants carrying the NS-segment of H5N1 HPAIV from either GD (FPV NS GD) or VN (FPV NS VN). Amino acid changes in the viral hemagglutinin and polymorphisms in the polymerase subunit have been shown to contribute to the virulence of AIV [42]. Amino acid differences or substitutions in the NS1 protein are described to alter its subcellular localization [44, 45]. Global Veterinaria 11 (5): 609-613, 2013 The Potential Role of Animals in the Epidemiology of Avian Influenza Virus H5N1 and Its Public Health Implications.

State Key Laboratory of Pathogen and Biosecurity (Beijing) - 2013 - Construction of a chimeric secretory IgA and its neutralization activity against Avian Influenza Virus H5N1. Kasetsart J. (Nat. Sci.) 47 : 720 - 732 (2013) Minimal Susceptibility to Highly Pathogenic Avian Infl uenza H5N1 Viral Infection of Pigeons (Columba livia) and Potential Transmission of the Virus to Comingled Domestic Chickens. Hong Kong Med J 2013;19(Suppl 4):S24-8 Replication and pathogenesis of avian influenza A (H5N1) virus infection in polarised human bronchial and alveolar epithelium. THE LANCET - DEC 2013 - Human infection with avian influenza A H6N1 virus: an epidemiological analysis. To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect.

Figure 1. Viruses 2013, 5(8), 1964-1977 Avian Influenza: Mixed Infections and Missing Viruses. International Journal of Scientific & Engineering Research, Volume 4, Issue 6, June-2013 617 Epitope designing on avian influenza disease. International Journal of Scientific & Engineering Research, Volume 4, Issue 6, June-2013 617. Babes-Bolyai University 11/02/14 Avian Influenza Surveillance in the Danube Delta using Sentinel Geese and Ducks. Theor Popul Biol. Dec 2013; 90(100): 135–144. Economic epidemiology of avian influenza on smallholder poultry farms. AVIA PATHOLOGY - 2013 - Differences in highly pathogenic avian influenza viral pathogenesis and associated early inflammatory response in chickens and ducks. WebImagesPlus… JOURNAL OF INFECTIOUS DISEASE 29/10/14 How Low Is the Risk of Influenza A(H5N1) Infection? For over a decade, we have heard predictions that avian influenza A(H5N1) may be nearing pandemicity and that the pandemic will be catastrophic when it arrives.

These predictions derive from a belief that A(H5N1) may be only a few mutations away from full adaptation to transmissibility [1] and from its allegedly high propensity to infect and to kill people. The World Health Organization (WHO) has recorded a case-fatality ratio of 59% among the 650 human cases reported to date [2], which some interpret to mean that approximately 60% of everyone infected by A(H5N1) will die. In the current climate of alarm, routine and decades-old virologic research approaches, such as examining the effects of engineered mutations on phenotypic properties like experimental virulence and transmissibility, recently termed “gain of function” studies, have been called “absolutely crazy” and “exceedingly dangerous” (Robert May, as quoted in Ref. [3]). GENOME 25/09/14 Complete Genome Sequence of a Novel Reassortant Avian Influenza H9N9 Virus Isolated from Chicken in Eastern China. AVIAN PATHOLOGY - JUNE 2003 - Seroprevalence of avian influenza virus and its relationship with increased mortality and decreased egg production.

PNAS 28/05/13 Interventions for avian influenza A (H5N1) risk management in live bird market networks. Instituto de Investigación en Recursos Cinegéticos - Poster : Serological Testing for Avian Influenza Viruses in Wild Birds: Comparison of Two Commercial Competition ELISAs. Air Water Borne Diseases 2015, 4:1 Potential Role of Fresh Water Apple Snails on H5N1 Influenza Virus Persistence and Concentration in Nature. FRONTIERS IN MICROBIOLOGY 06/11/15 Biosurveillance of avian influenza and Newcastle disease viruses in the Barda region of Azerbaijan using real time RT-PCR and hemagglutination inhibition. Introduction. Indian J Med Res 139, May 2014, pp 782-785 Pathogenicity of avian influenza H11N1 virus isolated from wild aquatic bird Eurasian Spoonbill (Platalea leucorodia)

Pakistan journal of zoology. 10/2011; 43(5). Study on Pathogenesis of Low Pathogenic Avian Influenza Virus H9 in Broiler Chickens. Rev. Bras. Cienc. Avic. vol.16 no.2 Campinas Apr./June 2014 Evaluation of a commercial ELISA kit (IDEXX) to differentiate AI virus-infected poultry from AI-vaccinated poultry (DIVA) JOURNAL OF VIROLOGY 29/04/15 Newcastle disease virus-vectored H7 and H5 live vaccines protect chickens from challenge with H7N9 or H5N1 avian influenza viruses. Ecohealth. 2009 Sep;6(3):449-57. ONCFS - The Potential Distance of Highly Pathogenic Avian Influenza Virus Dispersal by Mallard, Common Teal and Eurasian Pochard. Virol Sin. 2015 Jul 31. Identification of a novel strain of influenza A (H9N2) virus in chicken.

WATTAG 07/05/15 Analysis: Solutions for trade during avian influenza outbreak. The well isolated Cobb complex in Agua Clara, Mato Grosso do Sul, Brazil, with three rearing and six production units. The recommendations for compartments in the OIE’s Terrestrial Code cannot be applied in all situations. The effective implementation of the concept depends, amongst other things, on the epidemiology of the disease, individual country factors, environmental factors, biosecurity measures which may be applicable, the health status of adjacent areas, surveillance and the relationship between the public and private sectors. Journal of virological methods 10/2013; Rapid molecular haemagglutinin subtyping of Avian Influenza isolates by specific real-time RT-PCR tests.

Sélection par revues

Current Infectious Disease Reports 05/12/14 Avian Influenza: Recent Epidemiology, Travel-Related Risk, and Management. H5N1 influenza continues to smolder in Southeast Asia over the past 5 years, but the emergence of H7N9 in China in 2012 raised concerns for a new avian influenza threat. In contrast with H5N1 with over 650 confirmed cases over 11 years, H7N9 has infected over 450 persons within 2 years. The case fatality rate for H7N9 (35 %) is lower than for H5N1 (60 %) or H10N8 (67 %) but is comparable to that for the Middle East respiratory syndrome coronavirus (MERS CoV), another emerging zoonosis with travel-associated importations. AVIAN PATHOLOGY - JUNE 2003 - Seroprevalence of avian influenza virus and its relationship with increased mortality and decreased egg production. JOURNAL OF INFECTIOUS DISEASE 29/10/14 How Low Is the Risk of Influenza A(H5N1) Infection? PEERJ 30/10/14 A global phylogenetic analysis in order to determine the host species and geography dependent features present in the evolution of avian H9N2 influenza hemagglutinin.

Scientifica Volume 2014 (2014), A Review of the Antiviral Susceptibility of Human and Avian Influenza Viruses over the Last Decade. REVISTA 21 (2): 94-103, 2013 INFLUENZA H5N1 - NEXT PANDEMIC? Trakia Journal of Sciences, No 1, pp 59-64, 2014 SHEDDING OF THE AVIAN INFLUENZA A H6N2 SUBTYPE VIRUS ISOLATE IN NUMIDA MELEAGRIS. VETERINARY RESEARCH 04/06/14 High doses of highly pathogenic avian influenza virus in chicken meat are required to infect ferrets. NEW SCIENTIST 11/06/14 Wild bird flu could mutate into deadly human pandemic. AVIANINFLUENZA_ORG - The Economic and Social Impacts of Avian Influenza. VIROLOGY JOURNAL - 2013 - Systemic distribution of different low pathogenic avian influenza (LPAI) viruses in chicken. INFLUENZA RESEARCH AND TREATMENT - 2013 - Monoclonal Antibody Targeting Neutralizing Epitope on H5N1 Influenza Virus of Clade 1.

Selected Paper prepared for presentation at the Agricultural & Applied Economics Association’s 2013 AAEA & CAES Joint Annual Mee.

Selected Paper prepared for presentation at the Agricultural & Applied Economics Association’s 2013 AAEA & CAES Joint Annual Meeting, Washington, DC, August 4- 6, 2013 Impacts of BSE and Avian Influenza on U.S. Meat Demand – guatemalt

MEAT POULTRY 22/08/13 Ducks hosts for a variety of bird flu viruses. INFLUENZA RESEARCH AND TREATMENT 16/08/13 Comparative Serological Assays for the Study of H5 and H7 Avian Influenza Viruses. Sensors 2012, 12, 12506-12518; A SPR Aptasensor for Detection of Avian Influenza Virus H5N1. Clinical Infectious Diseases 05/02/13 Assessment of Serosurveys for H5N1. Influenza Research and Treatment Volume 2012 (2012) Persistence of Avian Influenza Viruses in Various Artificially Frozen Enviro. Viruses 2013, 5, 1431-1446; Viral and Host Factors Required for Avian H5N1 Influenza A Virus Replication in Mammalian Cells. Selected Paper prepared for presentation at the Agricultural & Applied Economics - Association’s 2011 AAEA & NAREA Joint Annual.

POULTRY SCIENCE - AOUT 2008 - Consumer Knowledge and Risk Perceptions of Avian Influenza. Veterinary Research Vol. 41 No. 3 (May-June 2010) Anthropogenic factors and the risk of Highly Pathogenic Avian Influenza H5N1: Journal of Biological Research-Thessaloniki 15: 135 – 144, 2011 Tracking possible ways of transmission of the highly pathogenic. NSF 06/07/10 Borne on the Wing: Avian Influenza Risk in U.S. Wild Songbirds Mapped. EcoHealth 6, 58–70, 2009 Industrial Food Animal Production and Global Health Risks: Exploring the Ecosystems and Economics of Av.

LLOYDS - PANDEMIC POTENTIAL INSURANCE IMPACTS. International Institute for Sustainable Development (IISD) 14/04/06 SCIENTIFIC SEMINAR ON AVIAN INFLUENZA, THE ENVIRONMENT AND M. CIDRAP 20/02/08 Avian Influenza (Bird Flu): Agricultural and Wildlife Considerations. Bull Vet Inst Pulawy 50, 287-291, 2006 MOLECULAR METHODS FOR THE DETECTION OF AVIAN INFLUENZA TYPE A VIRUSES. Avian Pathology (June 2006) 35(3), 189-205 The challenge of avian influenza to the veterinary community. Viruses 2012, 4, 3179-3208 Insight into Alternative Approaches for Control of Avian Influenza in Poultry, with Emphasis on Highl. CONGRESSIONAL RESEARCH SERVICE 12/07/12 Publishing Scientific Papers with Potential Security Risks: Issues for Congress. Au somm. International Journal of Poultry Science 8 (5): 462-464, 2009 Assessment of Pathogenic Potential of Avian Influenza Viruses by M. Selected Paper prepared for presentation at the Agricultural & Applied Economics Association 2009 AAEA & ACCI Joint Annual Meeti.

Selected Paper prepared for presentation at the Agricultural & Applied Economics Association 2009 AAEA & ACCI Joint Annual Meeting, Milwaukee, Wisconsin, July 26-29, 2009 Avian Influenza Threat and its Potential Impact on Demand for Chicken and Eggs – guatemalt

JOURNAL OF VIROLOGY - JULY 2011 - Antigenic Drift in H5N1 Avian Influenza Virus in Poultry Is Driven by Mutations in Major Antig. NATURE 03/05/12 Mutant-flu paper published - Controversial study shows how dangerous forms of avian influenza could evolve in th. 1753-6561-8-S6-S1.pdf.