VIRUSES 04/11/20 Portable Rabies Virus Sequencing in Canine Rabies Endemic Countries Using the Oxford Nanopore MinION. Gigante, C.M.; Yale, G.; Condori, R.E.; Costa, N.C.; Long, N.V.; Minh, P.Q.; Chuong, V.D.; Tho, N.D.; Thanh, N.T.; Thin, N.X.; Hanh, N.T.H.; Wambura, G.; Ade, F.; Mito, O.; Chuchu, V.; Muturi, M.; Mwatondo, A.; Hampson, K.; Thumbi, S.M.; Thomae, B.G.; de Paz, V.H.; Meneses, S.; Munyua, P.; Moran, D.; Cadena, L.; Gibson, A.; Wallace, R.M.; Pieracci, E.G.; Li, Y.
Portable Rabies Virus Sequencing in Canine Rabies Endemic Countries Using the Oxford Nanopore MinION. BMC Veterinary Research 08/06/20 Evaluation of a rapid immunochromatographic test kit to the gold standard fluorescent antibody test for diagnosis of rabies in animals in Bhutan. The use of rapid diagnostic tests in the field can greatly enhance disease surveillance, confirm clinical case and facilitate rapid response activities, especially in resource poor settings.
In the present study we have evaluated a commercially available rabies rapid kit produced by BioNote, Inc. (Hwaseong-si, Korea) for its fit-for-purpose for confirmation of clinical cases of rabies in animals for early response and enhancing rabies surveillance as recommended by OIE . We first screened all suspected rabies brain samples using the rapid test in the field and then re-confirmed by the FAT.
The results showed that the rapid test is highly sensitive and specific which agrees with findings from other studies conducted elsewhere (15-21). Other studies have also evaluated the rapid kit BioNote, Inc. Our study detected false negative results in 5.6% (10 of 179) of the samples relative to FAT. WELLCOMEOPENRESEARCH 19/05/20 Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes [version 2; peer review: 3 approved] 1 Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, G12 8QQ, UK2 The Boyd Orr Centre for Population and Ecosystem Health, University of Glasgow, Glasgow, G12 8QQ, UK3 University of Nairobi Institute of Tropical and Infectious Diseases (UNITID), Nairobi, Kenya4 Center for Global Health Research, Kenya Medical Research Institute, Nairobi, Kenya5 Paul G.
Kirstyn Brunker Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Gurdeep Jaswant Roles: Investigation S.M. Thumbi Roles: Funding Acquisition, Project Administration, Resources, Supervision Kennedy Lushasi Roles: Investigation Ahmed Lugelo Roles: Investigation Anna M. Fred Ade Roles: Resources. PLOS 06/03/20 Enabling animal rabies diagnostic in low-access areas: Sensitivity and specificity of a molecular diagnostic test from cerebral tissue dried on filter paper. Abstract Rabies is a lethal zoonotic encephalomyelitis that causes an estimated 59,000 human deaths yearly worldwide.
Although developing countries of Asia and Africa bear the heaviest burden, surveillance and disease detection in these countries is often hampered by the absence of local laboratories able to diagnose rabies and/or the difficulties of sample shipment from low-access areas to national reference laboratories. Filter papers offer a convenient cost-effective alternative for the sampling, shipment, and storage of biological materials for the diagnosis of many pathogens including rabies virus, yet the properties of diagnostic tests using this support have not been evaluated thoroughly. Author summary Dogs are responsible for 99% of human rabies deaths. Editor: Amy T. UNIV-BLIDA_DZ - JUIN 2019 - Thèse en ligne: ETUDE BIBLIOGRAPHIQUE SUR LRS ZOONOSES MAJEURS : LA RAGE, TUBERCULOSE, BRUCELLOSE. VIRUSES 31/10/19 Rabies Surveillance Identifies Potential Risk Corridors and Enables Management Evaluation. 1.
Introduction Intensive rabies management programs are implemented in the eastern United States and Canada to minimize the spread and eventually eliminate the raccoon variant of rabies virus. The primary method to manage the rabies virus (RABV) in wild carnivore populations is the use of oral vaccination at a landscape scale to reduce the susceptible portion of the population and consequently reduce transmission.
Modeling studies focused on raccoons estimate that population immunity levels of 60%–90% may be necessary to control and eliminate raccoon RABV circulation, but ultimately levels of population immunity are sensitive to variation in host density and contact across a rural-urban continuum [1,2,3]. To vaccinate wild carnivore populations, vaccine baits are distributed in target areas defined by the host epizootiology and landscape barriers where relevant, a process referred to as oral rabies vaccination (ORV).
PLOS 23/09/19 Rabies-induced behavioural changes are key to rabies persistence in dog populations: Investigation using a network-based model. Abstract Canine rabies was endemic pre-urbanisation, yet little is known about how it persists in small populations of dogs typically seen in rural and remote regions.
By simulating rabies outbreaks in such populations (50–90 dogs) using a network-based model, our objective was to determine if rabies-induced behavioural changes influence disease persistence. Behavioural changes–increased bite frequency and increased number or duration of contacts (disease-induced roaming or paralysis, respectively)–were found to be essential for disease propagation. Spread occurred in approximately 50% of model simulations and in these, very low case rates (2.0–2.6 cases/month) over long durations (95% range 20–473 days) were observed. Consequently, disease detection is a challenge, risking human infection and spread to other communities via dog movements. Author summary Editor: Thomas S. BMC VETERINARY RESEARCH 12/11/18 Paralytic rabies in a goat. PLOS 25/10/18 From recognition to action: A strategic approach to foster sustainable collaborations for rabies elimination. Citation: Octaria R, Salyer SJ, Blanton J, Pieracci EG, Munyua P, Millien M, et al. (2018) From recognition to action: A strategic approach to foster sustainable collaborations for rabies elimination.
PLoS Negl Trop Dis 12(10): e0006756. Editor: Charles E. Wistar Institute, Philadelphia VIA VIMEO - 2014 - "Rabies - A perpetual killer disease of humans challenges scientists, public health officials and governments" ANSES via DRAAF OCCITANIE 04/10/18 Présentation : Epidémiologie de la rage. Vet. Sci. 2018, 5(3), 67; A Perspective on Rabies in the Middle East—Beyond Neglect. 2.
Methods In this study, the following geographical locations, linking Africa, Europe, and Central Asia, were included subjectively as part of the Middle Eastern region: Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Jordan, Kuwait, Lebanon, Oman, Palestine, Qatar, Saudi Arabia, Syria, Turkey, the United Arab Emirates, and Yemen. The different localities of the Middle East discussed in this paper were organized according to the SARE framework. The rabies situation was then assessed to see if the SARE framework was sufficient and the regions were then ranked according to their obligation for rabies vaccination and whether rabies is endemic in that region or not. FRONT. VET. SCI 22/06/18 Understanding factors influencing dog owners’ intention to vaccinate against rabies evaluated using Health Belief Model constructs. 1College of Veterinary Medicine, Department of Diagnostic Medicine and Pathobiology, Kansas State University, United States 2College of Veterinary Medicine and Agriculture, Addis Ababa University, Ethiopia 3Atlantic Veterinary College, University of Prince Edward Island, Canada Ethiopia has one of the highest incidence levels of human rabies in Africa, with 3 to 7 deaths per 100,000 people annually.
The country has no official rabies control programme, despite the availability of an effective canine vaccine to control rabies. To support effective rabies control, an understanding of the factors affecting dog owners’ voluntary intentions to vaccinate their dogs is important. As such, this study examined factors influencing dog owners’ intentions to vaccinate their dogs using the constructs of health belief theory. Journal of Medical and Biological Science Research - NOV 2015 - A One-Health Approach to Control the Incidence of Rabies in the Slums of Nairobi. A One-Health Approach to Control the Incidence of Rabies in the Slums of Nairobi Mutembei HM, AE Cook, Muraya J, Makau DN, Aleri J, Kipyegon A and Mulei CM Research Paper I Published November,2015 Journal of Medical and Biological Science Research Vol. 1 (9), pp. 130-133 Rabies is a zoonotic disease causing 55,000 human deaths every year and the domestic dog is a main reservoir in Africa.
Israel Journal of Veterinary Medicine Vol. 73 (1) March 2018 Rabies Prophylactic Approaches. SCIENTIFIC RESEARCH - FEV 2018 - patiotemporal Analysis and Predictive Modeling of Rabies in Tennessee. 1. Introduction Spatially and temporally, diseases have earned a noticeable level of recognition worldwide. All life forms are continually threatened by imminent diseases, yet these phenomena have also provided topics of ongoing research and obstacles to overcome  . J Virol Methods. 2017 May; Development and validation of sensitive real-time RT-PCR assay for broad detection of rabies virus. Front. Vet. Sci., 31/08/17 Editorial: Towards Elimination of Dog Mediated Human Rabies. Editorial on the Research Topic Towards Elimination of Dog Mediated Human Rabies Rabies is a zoonotic viral disease with a high impact on human and animal health.
The disease is almost 100% fatal after clinical signs appear and kills tens of thousands of people per year worldwide. About 99% of infections in humans are caused by rabid domestic dog bites. Human disease is related to poverty, with the highest burden in Asian and African low-income settings. FRONTIERS IN VETERINARY SCIENCE 21/06/17 The Role of Dog Population Management in Rabies Elimination – A review of current approaches and future opportunities. 1Global Alliance for Rabies Control, United States 2Centers for disease Prevention and Control, United States 3Humane Society International, United States 4National Wildlife Research Center, United States Department of Agriculture, United States 5World Animal Protection, United Kingdom Free-roaming dogs and rabies transmission are integrally linked across many low income countries, and large unmanaged dog populations can be daunting to rabies control program planners.
Dog population management (DPM) is a multifaceted concept which aims to improve the health and well-being of free-roaming dogs, reduce problems they may cause, and may also aim to reduce dog population size. In theory, DPM can facilitate more effective rabies control. Community engagement focussed on promoting responsible dog ownership and better veterinary care could improve the health of individual animals and dog vaccination coverage, thus reducing rabies transmission. . * Correspondence: Dr. PERSPECTIVES IN MEDICAL RESEARCH - JANV-APRIL 2017 - Epidemiology and Public Health Significance of Rabies. PLOS 26/06/15 Development of a Novel Rabies Simulation Model for Application in a Non-endemic Environment. Abstract Domestic dog rabies is an endemic disease in large parts of the developing world and also epidemic in previously free regions.
For example, it continues to spread in eastern Indonesia and currently threatens adjacent rabies-free regions with high densities of free-roaming dogs, including remote northern Australia. Mathematical and simulation disease models are useful tools to provide insights on the most effective control strategies and to inform policy decisions. Existing rabies models typically focus on long-term control programs in endemic countries. However, simulation models describing the dog rabies incursion scenario in regions where rabies is still exotic are lacking. Author Summary Rabies in domestic dog populations still causes >50,000 human deaths worldwide each year.
Citation: Dürr S, Ward MP (2015) Development of a Novel Rabies Simulation Model for Application in a Non-endemic Environment. Copyright: © 2015 Dürr, Ward. DONNISH JOURNAL OF GENERAL AND MOLECULAR VIROLOGY - OCT 2015 - Antigenic and genetic stability of rabies virus. PLOS 05/10/16 Validation of a Rapid Rabies Diagnostic Tool for Field Surveillance in Developing Countries. Abstract Background One root cause of the neglect of rabies is the lack of adequate diagnostic tests in the context of low income countries.
A rapid, performance friendly and low cost method to detect rabies virus (RABV) in brain samples will contribute positively to surveillance and consequently to accurate data reporting, which is presently missing in the majority of rabies endemic countries. Probable Rabies Virus Transmission through Organ Transplantation, China, 2015 - Volume 22, Number 8—August 2016. Course: Ensemble des polycopiés de maladies contagieuses. University of Helsinki - 2008 - Department of Biological and Environmental Sciences - The community of medium-sized carnivores: the interactions between species, habitats and rabies.
Veterinary World VOLUME 2 - NO. 2 ( FEBRUARY-2009) Advances in diagnosis of rabies. Eurosurveillance monthly release: November 2005, volume 10, issue 11 DOSSIER RAGE. Weekly and monthly releases: Eurosurveillance releases: Trends in Infectious Diseases 23/04/14 Au sommaire: Trends in Research and Technology Development Related to Zoonosis Control Based on Bibliometric.
JOURNAL OF FOODBORNE AND ZOONOTIC DISEASES 29/03/14 Range of Rabies-A Review. INTEGRATED CONTROL OF NEGLECTED ZOONOSES 26/05/14 Vidéos en ligne concernant notamment la brucellose et la rage. J. Venom. Anim. Toxins incl. Trop. Dis vol.15 no.2 Botucatu 2009 On the interference of clinical outcome on rabies transmission an perpetuation. On the interference of clinical outcome on rabies transmission an perpetuation Brandão PE. Animals, Vol. 1, 2011 Investigation of an Imported Case of Rabies in a Juvenile Dog with Atypical Presentation. Animals 2011, 1, 326-342 Canine Rabies: A Looming Threat to Public Health. INTECH - NOV 2011 - Human Rabies Epidemiology and Diagnosis. INTECH - NOV 2011 - Human Rabies Epidemiology and Diagnosis. International Journal of Health Geographics 2011, 10:48 Advancements in web-database applications for rabies surveillance(Etude. Site Web de Jean-Luc GUESDON // CSTVN.FREE.FR. Visioconférences du 3 août 2009 La rage : aspects cliniques et épidémiologiques.