Etlik Vet Mikrobiyol Derg, 2017; 28 (2): 69-72 Detection of a Mixed Infection of Lumpy Skin Disease Virus and Foot and Mouth Disease Virus in a Calf. BIORXIV 08/10/20 Isolation and characterization of lumpy skin disease virus from cattle in India. BIORXIV 26/08/20 Quantifying and modelling the acquisition and retention of lumpy skin disease virus by haematophagus insects reveals clinically but not subclinically-affected cattle are promoters of viral transmission and key targets for control of disea. BIORXIV 13/08/20 Retention of Lumpy Skin Disease Virus in Stomoxys Spp (Stomoxys Calsitrans, Stomoxys Sitiens, Stomoxys Indica) following intrathoracic inoculation, Diptera: Muscidae. BIORXIV 18/06/20 Quantifying the acquisition and retention of lumpy skin disease virus by haematophagus insects and the implications for transmission and control. SCIENTIFIC REPORTS 04/05/20 Non-vector-borne transmission of lumpy skin disease virus.
Clinical observations Body temperature The baseline average temperature for the animals before the trial was 38.4 °C.
All animals infected with LSDV at the outset of the trial (group IN) had fevers up to 40.7 °C (range 39.0 °C to 40.7 °C) on p.i. day 3, indicating virus replication and circulation. By day 8 p.i., the body temperatures of all the inoculated bulls rose above 39.6 °C and their temperatures remained high until p.i. day 20, and thereafter moderate declines were measured to within the range of 38.1 to 39.6 °C in most of the infected animals up to around day 40 p.i. – thereafter a second bout of fever (bi-phasic) was measured in most of the group (except for NI-8) with temperatures rising to a high of 41.5 °C (IN-2) on day 41 p.i., tailoring off to close to normal levels from day 48 p.i.
(Fig. 1 and S1 Table). Average body temperature measurements per group over the course of the trial (orange – IN bulls, blue – C1 bulls, grey – C2 bulls). Edema Viremia. VIROLOGY JOURNAL 10/03/20 Suitability of individual and bulk milk samples to investigate the humoral immune response to lumpy skin disease vaccination by ELISA. Lumpy skin disease (LSD) is a vector-borne disease of cattle caused by lumpy skin disease virus (LSDV) which belongs to genus Capripoxvirus [1, 2].
Clinically, the disease can manifest in a wide spectrum ranging from severe acute to sub-acute and in-apparent forms. Typical signs observed are fever, enlargement of lymph nodes, nasal discharge, and firm skin nodules . The control of LSD is mainly based on mass vaccination of the susceptible cattle population with live attenuated capripoxvirus vaccine [4, 5]. Recent studies suggest that LSDV vaccination stimulates equally cell mediated and humoral immunity [6,7,8]. EFSA 27/02/20 Lumpy skin disease epidemiological report IV: data collection and analysis. Virus Research Volume 269, August 2019, Transmission of lumpy skin disease virus: A short review. TRANSBOUNDARY AND EMERGING DISEASES 30/04/19 Using the basic reproduction number to assess the risk of transmission of lumpy skin disease virus by biting insects.
Lumpy skin disease (LSD) is an important transboundary disease of cattle and is caused by lumpy skin disease virus (LSDV).
Historically, LSD outbreaks have largely been confined to Africa (EFSA Panel on Animal Health & Welfare, 2015), where the disease contributes to rural poverty and food insecurity (Molla, de Jong, Gari, & Frankena, 2017; Tuppurainen & Oura, 2012). In recent years, however, LSDV has emerged as a major threat to cattle outside of Africa. In 2012 it spread to the Middle East, through Israel and the Lebanon, reaching Turkey in 2013 (Alkhamis & VanderWaal, 2016). In 2015, the first cases of LSD were reported in Greece (Tasioudi et al., 2016) and the virus subsequently spread to much of the Balkans (Mercier et al., 2018). Evidence from the field and from experiments indicates that transmission of LSDV by most direct and indirect routes is inefficient (Carn & Kitching, 1995; Weiss, 1968). 2.1 Basic reproduction number for LSDV. TRANSBOUNDARY AND EMERGING DISEASES 25/05/19 Mapping changes in the spatiotemporal distribution of lumpy skin disease virus.
Lumpy skin disease virus (LSDV) is an infectious disease of cattle transmitted by arthropod vectors which results in substantial economic losses due to impact on production efficiency and profitability, and represents an emerging threat to international trade of livestock products and live animals.
Since 2015, the disease has spread into the Northern Hemisphere including Azerbaijan, Kazakhstan, the Russian Federation and the Balkans. The rapid expansion of LSDV in those regions represented the emergence of the virus in more temperate regions than those in which LSDV traditionally occurred. The goal of this study was to assess the risk for further LSDV spread through the (a) analysis of environmental factors conducive for LSDV, and (b) estimate of the underlying LSDV risk, using a combination of ecological niche modelling and fine spatiotemporally explicit Bayesian hierarchical model on LSDV outbreak occurrence data.
SCIENDO 29/03/19 Detection of antibodies against Lumpy skin disease virus by Virus neutralization test and ELISA methods. Medical and Clinical Archives - 2019 - Comparative studies on lumpy skin disease virus in human. FVE 13/11/18 3 questions about lumpy skin disease. FRONTIERS 27/09/19 The spatiotemporal distribution of lumpy skin disease virus. This project was funded by the Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, provided startup funds for GM and JA.
Additionally, the University of Minnesota Academic Health Center Grant-in-Aid program also provided funding the recipient of a Ramón y Cajal postdoctoral contract from the Spanish Ministry of Economy, Industry and Competitiveness (MINECO) (RYC-2016-20422). Chihota, C.M., Rennie, L.F., Kitching, R.P., Mellor, P.S., 2001. AGES_AT 07/02/20 Lumpy Skin Disease. BMC RESEARCH 01/07/19 A real-time PCR screening assay for the universal detection of lumpy skin disease virus DNA. Methods Primers and probe The assay was designed based on a target that offers a unique identification locus to facilitate the sensitive and specific detection of LSDV.
For designing candidate primers and probes, complete genome nucleotide sequences from all known LSDV strains as well as sheep pox viruses (SPPV) and goat pox viruses (GTPV) were recovered from GenBank and aligned using Bioedit to select the target region (Fig. 1). Nucleotide alignment of the probe targeted gene sequence of LSDVs. International Scholarly and Scientific Research & Innovation - 2017 - Establishing Econometric Modeling Equations for Lumpy Skin Disease Outbreaks in the Nile Delta of Egypt under Current Climate Conditions.
Zm_gov_lv 04/10/18 Présentation : EMERGENCY VACCINATION LUMPY SKIN DISEASE. Journal of Virological Methods Available online 16 December 2019 An Immunoperoxidase Monolayer Assay (IPMA) for the detection of lumpy skin disease antibodies. Afayoa et al., 2014 M.
Afayoa, D.K. Atuhaire, S. Ochwo, J.B. EFSA 29/11/19 Lumpy skin disease: Workshop on risk assessment and data collection for epidemiology, control and surveillance ‐ November 2019. TRANSBOUNDARY AND EMERGING DISEASES 30/04/19 Using the basic reproduction number to assess the risk of transmission of lumpy skin disease virus by biting insects. Lumpy skin disease (LSD) is an important transboundary disease of cattle and is caused by lumpy skin disease virus (LSDV).
Historically, LSD outbreaks have largely been confined to Africa (EFSA Panel on Animal Health & Welfare, 2015), where the disease contributes to rural poverty and food insecurity (Molla, de Jong, Gari, & Frankena, 2017; Tuppurainen & Oura, 2012). In recent years, however, LSDV has emerged as a major threat to cattle outside of Africa.
In 2012 it spread to the Middle East, through Israel and the Lebanon, reaching Turkey in 2013 (Alkhamis & VanderWaal, 2016). In 2015, the first cases of LSD were reported in Greece (Tasioudi et al., 2016) and the virus subsequently spread to much of the Balkans (Mercier et al., 2018). Evidence from the field and from experiments indicates that transmission of LSDV by most direct and indirect routes is inefficient (Carn & Kitching, 1995; Weiss, 1968). BMC VETERINARY RESEARCH 08/07/19 Seroprevalence and risk factors for lumpy skin disease virus seropositivity in cattle in Uganda. EUREKALERT 29/05/19 Model identifies high-risk areas for lumpy skin disease in cattle. Researchers have combined two separate computer models to identify areas at highest risk for outbreaks of lumpy skin disease virus (LSDV) in cattle.
The models could help officials determine where to send resources ahead of outbreaks and serve as a potential early warning system for cattle farmers in affected areas. LSDV is a disease that affects cattle. Current research points to transmission via biting insects such as flies, fleas, ticks or mosquitoes. Infected calves may die, and older cattle develop bleeding circular lesions on the skin, decreased milk production, and overall poor health. Although LSDV is endemic to Africa, since 2015 the disease has spread into the Northern Hemisphere including Azerbaijan, Kazakhstan, the Russian Federation and the Balkans. The model identified elevated risk areas in Russia, Turkey, Serbia and Bulgaria. Although LSDV hasn't yet been reported in the U.S., Machado says his model could easily be used to predict high-risk areas if an outbreak occurs.
EFSA VIA YOUTUBE 21/03/19 LSD outbreaks and vaccination in South Eastern Europe. EFSA 21/03/19 Lumpy skin disease III. Data collection and analysis. EFSA 23/11/18 Lumpy skin disease: Workshop on risk assessment and data collection for epidemiology, control and surveillance. EFSA 16/10/18 Lumpy skin disease: scientiﬁc and technical assistance on control and surveillance activities. The duration of the vaccination campaign sufﬁcient to eliminate lumpy skin disease (LSD) mainly depends on the vaccination effectiveness and coverage achieved.
By using a spread epidemiological model, assuming a vaccination effectiveness of 65%, with 50% and 90% coverage, 3 and 4 years campaigns, respectively, are needed to eliminate LSD. When vaccination effectiveness is 80% to 95%, 2 years of vaccination at coverage of 90% is sufﬁcient to eliminate LSD virus (LSDV). For shorter campaigns, LSD is predicted to persist. When the infection is eliminated by vaccination, two pathways for disease recurrence are possible, (i) by new introduction from a neighbouring affected area, especially by introduction of infected animals, or, less likely (ii) the infection persisting either in the environment, in vectors or in wild animals. FAO has published a new manual, which is part of the FAO animal production and health series: Lumpy skin disease - A field manual for veterinarians. This manual is aimed to those in the first line of defence, i.e. those working in the field, who are most likely to encounter this vector-borne, viral disease that afflicts cattle.
The manual provides veterinary professionals and paraprofessionals (in the field and in slaughterhouses) and laboratory diagnosticians with the information they need to promptly diagnose and respond to an outbreak of lumpy skin disease (LSD). Cattle farmers will also benefit from reading it. Characterized by nodules on the skin, LSD is primarily transmitted by mosquitoes, other hematophagous insects, and flies.
In addition to vectors, transmission may occur through consumption of contaminated feed or water, direct contact, natural mating or artificial insemination. LSD was long limited to sub-Saharan Africa. Share: CODA CERVA 03/10/17 Présentation : Lumpy skin disease: an emerging disease? EFSA VIA YOUTUBE 06/04/18 Lumpy skin disease vaccination programme in Europe (Jan 2016-Dec 2017) EFSA 19/02/18 Lumpy skin disease II. Data collection and analysis. EFSA 19/02/18 Lumpy skin disease: vaccination leads to fall in outbreaks.
Outbreaks of lumpy skin disease (LSD) in the Balkan region fell dramatically by 95% from 7,483 in 2016 to 385 in 2017. The figures confirm that vaccination of cattle – recommended by EFSA in 2016 – is the most effective way to contain the disease. A report published today by EFSA gives an update on the occurrence of LSD and the effectiveness of vaccination. It also analyses the risk factors for its spread in south-eastern Europe. The report is based on data collected by affected countries and those at risk. However, Alessandro Broglia, a veterinarian at EFSA, warned: “Even if the number of outbreaks has decreased significantly, the disease has not been eliminated from the region yet and therefore we need to remain vigilant.”
In 2017 most of the outbreaks – 379 – were reported in areas of Albania where the vaccination programme had not yet been completed. Working together The cooperation and commitment of countries involved in the data collection was crucial for the report. Veterinary Research 2012 43:1 Mathematical modelling and evaluation of the different routes of transmission of lumpy skin disease virus.
The results of this study indicate that in the outbreak described, transmission of LSDV by direct contact had only a minor effect on virus spread. These findings were found to be very robust to various assumptions regarding mean and standard deviation of incubation period and regarding the existence of subclinical infection.
Low significance of direct transmission as opposed to the high relative importance of indirect transmission coincides with the outcome of previous experimental studies [8, 9] and was supported by several findings from this study. The initial spread of the disease from the index case occurred simultaneously to 7 groups in the herd that had not been in any direct contact with each other. This suggests that the virus must have been transmitted by indirect routes. From a practical point of view, the results from this study imply that the contribution of indirect transmission to R0 is significantly higher than that of direct transmission.
In 2015 the disease entered Europe for the first time, resulting in the slaughter of thousands of cattle in Greece and neighbouring countries. Dr. Pip Beard from The Pirbright Institute is a leading expert on LSD and here she answers questions about the disease and the latest research, and explains the role Pirbright is playing to help combat its spread. PARLEMENT EUROPEEN - Réponse à question E-003316-17 Lumpy skin disease.
FAO 25/07/16 Report of FAO Ad Hoc Group Meeting on Lumpy Skin Disease. FAO - MARS 2017 - Présentations : Regional workshop on lumpy skin disease (LSD) prevention and control strategies. The FAO Regional Office for Europe and Central Asia has invited representatives from select national veterinary services to attend the Regional workshop on lumpy skin disease (LSD) prevention, control, and awareness raising, for the Balkans, Caucasus, and Eastern European regions. The workshop will take place at the Ministry of Agriculture in Budapest, Hungary on 7-9 March 2017, and is jointly organised through a combination of funds from the technical cooperation programme and a donation by the Hungarian Government.
Given the progressive transboundary spread of LSD, a regional approach to control the disease in the region is recommended, i.e. a common approach by all neighbouring countries, either already affected or those that will likely become infected in the coming months. Presentations. FAO - MAI 2017 - Présentations : Second regional workshop on lumpy skin disease (LSD) prevention, control, and awareness raising. With the progressive transboundary spread of LSD, a harmonized regional approach to control the disease in the region is highly recommended. This second regional workshop provided an opportunity for countries in the region, both affected and at immediate risk, to share their experiences, to improve their knowledge, and to discuss in an open forum with the aid of experts some of the most challenging issues faced by veterinary services when it comes to LSD prevention and control.
Lessons learnt and practical effective and efficient solutions were targeted. EUROPE 13/01/15 Présentation : Exotic diseases approaching EU EFSA mandates on PPR, sheep pox, lumpy skin disease. EUROPE 14/09/16 Exotic animal diseases: The Commission and the Member States move to a more preventive strategy for Lumpy Skin Disease. BENHA VETERINARY MEDICAL JOURNAL, VOL.31,NO.2:1-7,DECEMBER,2016 Preparation and field evaluation of live attenuated sheep pox vaccine for protection of calves against lumpy skin disease. PARLEMENT EUROPEEN - Réponse à question E-003316-17 : Lumpy skin disease. FRONTIERS IN VETERINARY SCIENCE 03/03/16 Spatial and Temporal Epidemiology of Lumpy Skin Disease in the Middle East, 2012–2015. Introduction. COMMISSION EUROPEENNE 18/05/17 Présentation : European Union Lumpy Skin Disease and other exotic diseases antigen/vaccine banks Current status, policy and future considerations.
TRANSBOUNDARY AND EMERGING DISEASES 26/02/17 Spread rate of lumpy skin disease in the Balkans, 2015–2016. PARLEMENT EUROPEEN - Réponse à question P-007744-16 Spread of lumpy skin disease. FAO - 2016 - IN ACTION Emergence of lumpy skin disease in Asia and Europe. FOOD AND VETERINARY AGENCY MADEDONIA via OIE 07/04/16 Lumpy Skin Disease in Republic of Macedonia. PARLEMENT EUROPEEN - Réponse à question E-006178-16 Measures at regional level to contain lumpy skin disease, a contagious disorder affecting cattle. EUROPE 14/09/16 Exotic animal diseases: The Commission and the Member States move to a more preventive strategy for Lumpy Skin Disease. PARLEMENT EUROPEEN - Réponse à question P-006154-16 Vaccination against contagious bovine lumpy skin disease. FLI_DE - SEPT 2016 - Carte de répartion Lumpy Skin Disease au 06/09/16. Die Lumpy Skin Disease (LSD) ist eine anzeigepflichtige Tierseuche des Rindes, die durch Capripox-Viren verursacht wird.
Die LSD kommt in Afrika und im Nahen Osten endemisch vor. Krieg und Vertreibung begünstigten eine Ausbreitung der Tierseuche aus Krisengebieten in die angrenzenden Staaten und letztlich nach Europa. In Südosteuropa sind die Fallzahlen von LSD in den letzten Monaten stark angestiegen und die Krankheit breitet sich vom Balkan stark in nordwestliche Richtung aus. Die Übertragung findet hauptsächlich über Arthropoden statt. Epidemiologische Situation LSD ist in den meisten afrikanischen Ländern endemisch und wurde seit 2012 im Mittleren und Nahen Osten festgestellt. Krankheitssymptome Klinisch erkrankte Tiere zeigen Fieber und später typische Hautveränderungen Diese knötchenartigen (nodulären) Läsionen können auch sehr dezent ausfallen und sind teilweise nur durch Ertasten feststellbar Regelmäßig sind auch das Euter und die Zitzen von Hautveränderungen betroffen.
EUROPE 13/01/15 Présentation : Exotic diseases approaching EU EFSA mandates on PPR, sheep pox, lumpy skin disease. FAS USDA 13/07/16 Contagious Lumpy Skin Disease Hits Cattle in Serbia_Belgrade_Serbia_7-8-2016. BMC Veterinary Research 2015, 11:135 Sero-prevalence of lumpy skin disease in selected districts of West Wollega zone, Ethiopia. Description of study areas. Animal Supply Chain and Animal Welfare Department (NL) 19/03/15 Contingency plan - Lumpy skin disease. Animal and Veterinary Sciences - MARS 2015 - Epidemiology, Economic Importance and Control Techniques of Lumpy Skin Diseases.
EFSA - JANV 2015 - Présentation : Exotic diseases approaching EU EFSA mandates on PPR, sheep pox, lumpy skin disease. EUROPE - JANV 2015 – Présentation : Mission of the Community Veterinary Emergency Team to Cyprus SCOPE of the mission: Lumpy skin disease in cattle in Cyprus. ARC - LNR - MARS 2015 - SOCIO-ECONOMIC IMPACTS OF LUMPY SKIN DISEASE AND RIFT VALLEY FEVER ON THE SOUTH AFRICAN LIVESTOCK ECONOMY. Ticks and Tick-borne Diseases Volume 6, Issue 2, March 2015, Lumpy skin disease: Attempted propagation in tick cell lines and presence of viral DNA in field ticks collected from naturally-infected cattle.
Open Access Abstract. EFSA 13/01/15 Scientific Opinion on lumpy skin disease. Following a request from the European Commission, the EFSA Panel on Animal Health and Welfare (AHAW Panel) was asked to deliver a scientific opinion on lumpy skin disease (LSD), in order to provide an update on the characterisation of the disease; to assess the risk of introduction into the European Union (EU) and the speed of spread, the risk of becoming endemic and its impact; and to determine if further measures are justified. This request is linked to the recent and important spread of LSD throughout the Middle East, including Turkey, where it is now considered endemic.
Regarding disease characterisation, the AHAW Panel reported that LSD is characterised by significant losses, especially in naive and young animals, due to chronic debility, reduced milk production and weight, infertility, abortion and death, but it is not a zoonosis. LSD is endemic in most African countries. FOCUS 20/08/15 Bulgaria authorities stepping up preventive measures against lumpy skin disease. Home | Services | Archive | Partners | Banners | Radio Adds | About Us | Disclaimer | Contacts | © 2016 FOCUS Information Agency The content published by Focus Information Agency and the technologies, used on its website, are protected by the Copyright and Neighbouring Rights Act.
All the text, audio and video materials, photos, and graphics, published in the database, are property of Focus Information Agency, unless otherwise provided. The USERS and SUBSCRIBERS are under the obligation to use the materials from the database according to Focus Information Agency’s General Terms and Conditions as well as the applicable law of the Republic of Bulgaria. Ticks and Tick-borne Diseases Volume 4, Issue 4, June 2013, Pages 329–333 Evidence of vertical transmission of lumpy skin diseas.
ECOLES VETERINAIRES - Cours en ligne de législation vétérinaire - Ensemble des polycopiés de maladies contagieuses réalisés par les enseignants des unités de maladies contagieuses des écoles nationales vétérinaires françaises. – guatemalt
OIE - 2013 - Code sanitaire pour les animaux terrestres. HACHAKLAIT - 2012 - Lumpy skin disease outbreak in Israel 2012. CONFEDERATION SUISSE - MARS 2013 - Lumpy Skin Disease (Dermatose nodulaire contagieuse) International Journal of Bioscience, Biochemistry and Bioinformatics, Vol. 3, No. 4, July 2013 Abattoir-Based Survey and Histopa. FAO EMPRES - NOV 2013 -Emergence of lumpy skin disease in the Eastern Mediterranean Basin countries.