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SCIENCE ALERT 06/04/17 Evidence Emerges That Celiac Disease Could Be Triggered by a Seemingly Harmless Virus. PARLEMENT EUROPEEN - Réponse à question E-009318-15 European protocol for detecting coeliac disease. Studies have indicated that around 1% of the European population suffer from coeliac disease (an intolerance to gluten, which is present in a number of cereals such as wheat, barley and rye), yet only 10‐20% of those people have been correctly diagnosed.

PARLEMENT EUROPEEN - Réponse à question E-009318-15 European protocol for detecting coeliac disease

This means that over 80% of those who have the disease may not be aware of it. The European Union is sensitive to the situation created by this disease, and has already adopted regulations on the labelling of food that is gluten‐free, or very low in gluten, but it needs to make this sensitivity more tangible and transparent by introducing measures to help coeliac sufferers more directly. PARLEMENT EUROPEEN - Réponse à question E-008745-15 Discrimination and nutritional risks due to the high price of food for coeliac sufferers. One in every 80-100 citizens has coeliac disease.

PARLEMENT EUROPEEN - Réponse à question E-008745-15 Discrimination and nutritional risks due to the high price of food for coeliac sufferers

Treatment consists of a strict gluten-free diet for life. Nevertheless, basic products for coeliac sufferers are considerably dearer than ordinary food. According to a study by FACE (Spanish Federation of Coeliac Associations)(1), coeliac sufferers may find that their shopping basket costs an additional EUR 1 500 per year — 265% more than an ordinary shop. There are considerable differences in the aid Member States give to coeliac sufferers — such as gluten-free products available free of charge for children and the elderly, refunds for patients against production of the labels from purchased products, social security benefits, etc. — whereas in countries like Spain there is no support of any kind for those affected. Has the Commission carried out any kind of study or does it have any data on the extent to which prices are a factor in worsening the health of the coeliac population?

PARLEMENT EUROPEEN - Réponse à question E-012148-15 Prevalence of coeliac disease among Sahrawi refugees. Several studies show that the prevalence of coeliac disease caused by gluten intolerance among the population of Western Sahara is 6%, one of the highest in the world.

PARLEMENT EUROPEEN - Réponse à question E-012148-15 Prevalence of coeliac disease among Sahrawi refugees

This factor is of particular concern for Sahrawis who have been forced by Morocco’s illegal invasion to live in the refugee camps in Tindouf, in southern Algeria. They are dependent on humanitarian aid, and most of the food provided contains gluten. As a result, they are unable to follow the diet that currently offers the only effective treatment for people with this disease, which affects various organs such as the intestines, liver, thyroid gland, skin and reproductive system. Coeliacs who do not follow this diet face a greater risk of dying from the associated conditions, chiefly cancer — intestinal lymphoma, tongue and oesophageal cancer, etc. — as well as cardiovascular diseases and complications such as diabetes and osteoporosis.

Journal of AOAC International. 07/2011 Analytical methods for detection of gluten in food-method developments in support of food labeling legislation. FSA 16/05/11 'Gluten-free' guide published. ECONEWS 26/11/13 Can Genetically Modified Foods Trigger Gluten Sensitivity? A new report links genetically modified organisms (GMOs) with gluten-related disorders and suggests GMOs might be an important environmental trigger for gluten sensitivity, estimated to affect as many as 18 million Americans.

ECONEWS 26/11/13 Can Genetically Modified Foods Trigger Gluten Sensitivity?

The report, released by the Institute for Responsible Technology (IRT), cites U.S. Department of Agriculture data, U.S. Environmental Protection Agency records, medical journal reviews and international research. The authors say the data link GMOs to five conditions that either may trigger or exacerbate gluten-related disorders, including celiac disease, a serious autoimmune disorder: Intestinal permeabilityImbalanced gut bacteriaImmune activation and allergic responseImpaired digestionDamage to the intestinal wall Although wheat has been hybridized over the years, it is not a GMO, which can only be created by a laboratory process that inserts genetic material into plant DNA. Glyphosate is a patented antibiotic that destroys beneficial gut bacteria. BMC 06/11/14 Early diagnosis of celiac disease in IgA deficient children: contribution of a point-of-care test. The diagnosis of CD is a challenge for many physicians.

BMC 06/11/14 Early diagnosis of celiac disease in IgA deficient children: contribution of a point-of-care test

Unfortunately, up to 75% of CD remains undiagnosed, and the time between the onset of symptoms and diagnosis is often too long [20, 21]. It is thought that the use of a highly sensitive rapid point- of- care test, performed in primary care centers, may help physicians to rule out CD and to select patients on which more invasive diagnostic tests are required [22–24]. This strategy could allow a better and more reactive patient support, decreasing the time to diagnosis while increasing the patient quality of life.

According to the last ESPGHAN guidelines, the initial testing of patients suspected of CD should be the serological identification of IgA autoantibodies against tTG, followed by biopsy in case of a positive serology [8]. Journal of AOAC International. 07/2011 Analytical methods for detection of gluten in food-method developments in support of food labeling legislation. PARLEMENT EUROPEEN - Réponse à question E-009318-15 European protocol for detecting coeliac disease. WAGENINGEN UNIVERSITY 04/12/13 Prevalence of celiac disease in China higher than expected. In China, celiac disease is more common than has been reported, conclude researchers of Nanchang University (China), together with Dutch scientists of Wageningen UR (University & Research centre) and the University Medical Centre Groningen, within the framework of the Dutch Celiac Disease Consortium.

WAGENINGEN UNIVERSITY 04/12/13 Prevalence of celiac disease in China higher than expected

They conducted the first systematic review and meta-analysis of the Chinese and international literature on celiac disease. Celiac disease was considered to be rare in China and it had not been studied thoroughly, despite the fact that China is the world’s largest wheat producer and has a high and rapidly increasing consumption of wheat and gluten-containing products. LONDON SCHOOL OF ECONOMICS AND POLITICAL SCIENCE - 2012 - Resource use and costs associated with coeliac disease before and after diagnosis in 3,646 cases: results of a UK primary care database analysis.

HACCP EUROPA 09/04/14 Scientists Develop New Strategies To Treat Gluten Intolerance. Canadian and Swiss scientists have identified that Elafin is able to interact with enzymes responsible for the abnormal breakdown of gluten, reduces gluten toxicity.

HACCP EUROPA 09/04/14 Scientists Develop New Strategies To Treat Gluten Intolerance.

The discovery may lead to new strategies to treat gluten intolerance. Scientists from INRA and INSERM (France) in collaboration with scientists from McMaster University (Canada) and the Ecole polytechnique fédérale of Zurich (Switzerland) have shown that Elafin, a human protein, plays a key role against the inflammatory reaction typical of celiac disease (gluten intolerance). They have also developed a probiotic bacterium able to deliver Elafin in the gut of mice. This innovation, published online in the American Journal of Gastroenterology on 8 April 2014, paves the way to new strategies to treat gluten intolerance.

INFORMA 01/10/13 Evaluation of visual and taste preferences of some gluten-free commercial products in a group of celiac childre. EMAXHEALTH 19/08/11 Researchers stumped about the rise in celiac disease. Celiac disease, a gastrointestinal disorder characterized by an intolerance to gluten, a grain protein, is on the rise in the U.S. and no one is quite sure why.

EMAXHEALTH 19/08/11 Researchers stumped about the rise in celiac disease

But increasing amounts of people are being diagnosed yearly, prompting researchers to inquire as to the possible causes. According to one recent study, nearly five times as many people have celiac disease today than they did during the 1950s. Another report found that the rate of celiac disease has doubled every 15 years since 1974 and is now believed to affect one in every 133 U.S. residents. "It's quite widespread," said Dr. Alessio Fasano, director of the Center for Celiac Research and the Mucosal Biology Research Center at the University of Maryland School of Medicine. Researchers are testing a number of hypotheses about the new trend. The autoimmune attack damages the inner lining of the small intestine, compromising its ability to digest food and extract vital nutrients. The hypothesis has been voiced in allergy circles. LATVIA UNIVERSITY OF AGRICULTURE - 2012 - Annual 18th international scientific conference proceedings. Au sommaire: Consumers’ a.

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