Research & Reviews: Pharmacy and Pharmaceutical Sciences 27/10/16 Alternatives to Animal Experimentation. LABANIMAL - APRIL 2017 - Side effects of pain and analgesia in animal experimentation. Animals 2017, 7(3), 24; Conscientious Objection to Animal Experimentation in Italian Universities. UNILEVER 04/04/15 UNILEVER’S POSITION ON DEVELOPING ALTERNATIVE APPROACHES TO ANIMAL TESTING.
WAGENINGEN UNIVERSITY 07/10/15 Innovative neuron test detects unknown marine toxins and can replace animal testing. Marine toxins are toxins produced naturally by algae.
Shellfish such as mussels that feed on algae, can accumulate these toxins in their bodies. When a human or animal consumes contaminated shellfish, various symptoms of poisoning can occur, such as memory loss, abdominal cramps, diarrhoea or paralysis. Mice testing To test whether shellfish are free of such marine toxins, both chemical tests and, in most parts of the world, mice tests are used. In the mice test (which is not used in the Netherlands), an extract of the shellfish is injected into the mouse’s abdominal cavity. Neuronal cell line Nicolas’s research initially focused on toxins that can cause paralysis, called neurotoxins. VIB_BE 05/03/15 European researchers point to the importance of animal testing. Page Content Zone 1 More than hundred European scientific organizations, including VIB, oppose the citizens’ initiative Stop Vivisection to ban all research using animals in Europe.
With the support of these scientific organizations the Wellcome Trust (UK) has issued a clear statement which specifies that animal experimentation is still unavoidable to enable important breakthroughs in biomedical research. VETERINARY RECORD - 2015 - One Health: a concept led by Africa, with global benefits. ONE Health evolved from the recognition that an interdisciplinary approach is required to understand complex health problems, and that the health of humans and animals are inextricably linked.
Through closer cooperation between the human, veterinary and environmental health sectors, added value, in terms of health metrics, cost savings and environmental services is achievable. Although the One Health concept has been recognised for many years, particularly since the seminal work of Calvin Schwabe (Schwabe 1984), many challenges remain in making it operational.⇓ ‘Africa's National medical and veterinary institutions are still maturing, which presents African health professionals with an opportunity to build on an instinctive understanding of the connectivity between people, animals and their environments, and to “leapfrog” barriers imposed by more well-established and rigid institutional systems’
Regulatory Toxicology and Pharmacology Volume 73, Issue 1, October 2015, Knowledge sharing to facilitate regulatory decision-making in regard to alternatives to animal testing: Report of an EPAA workshop. Regulatory Toxicology and Pharmacology. 04/2010; A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: genotoxicity. A COLIPA analysis. Regul Toxicol Pharmacol. J Am Assoc Lab Anim Sci. 2015 Mar; 54(2): 209–213. The European Partnership for Alternative Approaches to Animal Testing (EPAA): Promoting Alternative Methods in Europe and Beyond. Réponses parlementaires Européennes. BIOMED CENTRAL BLOG 27/02/15 Reducing publication bias in animal research A workshop on publication bias in animal research reveals the importance of publishing negative results and the role of preclinical study registration. But is there a one-size solut.
This week the National Centre for the Replacement Refinement & Reduction of Animals in Research (NC3Rs) hosted a workshop on publication bias (supported by the Wellcome Trust).
The aim was to bring together researchers, funders, and journals, from academia and industry to discuss ways in which we can reduce publication bias in animal research (follow on twitter with #publicationbias). Publication bias occurs when the research that reaches the publication domain is not representative of the research that is done as a whole; typically null or ‘negative’ results are supressed. Evidence-based medicine pioneer and founder of the Cochrane Collaboration Sir Iain Chalmers has been vocal on the topic since the 1980s and praised the NC3Rs for bringing the issue to the forefront once more. BIOME 23/02/15 Making the most of animal research: from meta-analysis to trial registration. MAFNZ 28/06/11 Auckland scientist wins award for reducing animal testing. A University of Auckland scientist has been honoured for her work in the humane use of animals in scientific research, testing and teaching receiving the 2011 National Animal Ethics Advisory Committee (NAEAC) Three Rs award, sponsored by the Royal New Zealand SPCA.
Dr Siouxsie Wiles wins the award in recognition of her consistent adherence to Three Rs principles and the embodiment of them into her everyday work as a microbiologist says NAEAC chairperson, Dr Virginia Williams. “The concept of the Three Rs is to replace live animal subjects, reduce the number of animals used and refine experimental techniques to minimise pain and distress. Dr Wiles’ work embodies all three techniques, and reflects the underpinning philosophy that the use of animals in science is only acceptable if all efforts are made to minimise harm or suffering.”
More. MEDIATEUR EUROPEEN 11/12/14 Décision : Unnecessary tests on animals by registrants of chemical substances. PLOS 06/06/14 The Need for Randomization in Animal Trials: An Overview of Systematic Reviews. Background and Objectives Randomization, allocation concealment, and blind outcome assessment have been shown to reduce bias in human studies.
Authors from the Collaborative Approach to Meta Analysis and Review of Animal Data from Experimental Studies (CAMARADES) collaboration recently found that these features protect against bias in animal stroke studies. We extended the scope the work from CAMARADES to include investigations of treatments for any condition. Methods We conducted an overview of systematic reviews. Results Thirty-one systematic reviews met our inclusion criteria: 20 investigated treatments for experimental stroke, 4 reviews investigated treatments for spinal cord diseases, while 1 review each investigated treatments for bone cancer, intracerebral hemorrhage, glioma, multiple sclerosis, Parkinson's disease, and treatments used in emergency medicine.
Conclusions Figures Editor: Brett Thombs, McGill University, Canada Copyright: © 2014 Hirst et al. Introduction Figure 1. 1. 2. North-West University - Dec 2012 - Dissertation en ligne : Animal welfare and the law: towards legal regulation of the welfare of laboratory animals in South Africa. FDA 10/06/14 Product Testing. Cosmetics are required to be safe when consumers use them according to directions in the labeling, or in the customary or expected way.
Product testing is just one of the things a manufacturer might do to ensure the safety of a cosmetic product. Sometimes FDA conducts testing when we are investigating possible safety problems with a product or as part of our research program. FDA resources on cosmetic product testing are valuable to consumers and industry alike. Who’s Responsible for the Safety of Cosmetics? FDA does not have the legal authority to approve cosmetic products and ingredients (other than color additives) before they go on the market. The law treats color additives differently. Using Available Safety Data to Support the Safety of Your Cosmetic Manufacturers can use safety data that is already available on individual ingredients and on products with similar formulations.
Cosmetic ingredient suppliers often have safety data on their products. NIH_GOV 07/10/14 Alternatives to Animal Testing - Questions and Answers about ICCVAM. Introduction What are alternative test methods?
Alternative test methods are test methods that reduce, refine, or replace animal use in research and testing. Reduction, refinement, and replacement are commonly referred to as “the 3Rs”. Environments 2014, 1, 14-30 Review of Evidence of Environmental Impacts of Animal Research and Testing.
North-West University - Dec 2012 - Dissertation en ligne : Animal welfare and the law: towards legal regulation of the welfare o. ALTEX - SEPT 2012 - 17th European Congress on Alternatives to Animal Testing. PHYSORG 13/11/12 Artificial liver to replace animal testing, potential to accelerate development of new drugs. Medicolegal and Bioethics 2012:2 13–29 REACH, animal testing, and the precautionary principle. Acta Cir. Bras. vol.27 no.9 São Paulo Sept. 2012 Progress in animal experimentation ethics. A case study from a Brazilian medica. Progress in animal experimentation ethics.
A case study from a Brazilian medical school and from the international medical literature1 Progresso na ética em experimentação animal. O estudo de caso de uma escola médica brasileira e da literatura médica internacional Edvaldo Luiz Ramalli Jr.I; Wanli HoI; Mônica AlvesII; Eduardo Melani RochaIII IGraduate student, Faculty of Medicine of Ribeirao Preto, USP, Sao Paulo, Brazil. Correspondence. THE GUARDIAN 19/10/12 Public opposition to animal testing grows. Trust in scientists and the rules governing the practice of animal testing is falling, the new research shows. Photograph: Natacha Pisarenko/AP Public opposition to the use of animals in medical research is growing and trust in both scientists and the rules governing the controversial practice is falling, new government-funded research shows.
More than one in three people (37%) now class themselves as "objectors" to the practice. Their number has been rising steadily since the 29% recorded in 2006 and 35% seen in 2010, though is still lower than the 39% found in 2002, according to the latest research into public attitudes on the issue by Ipsos MORI.