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KGML-ED allows the dynamic exploration and editing of KEGG Pathway diagrams. It is a graphical network editor, that provides read- and write-support for the KGML (KEGG Markup Language) file format. Pathway files are loaded and transformed into a graph network which may be modified to fulfill user-specific needs (e.g. it is possible, to delete or add network elements, change labels and colors). (1) The navigation from overview to detail (construct a pathway overview and integrate/load selected pathways into the view). (2) The exploration of related pathways by integrating referenced pathway maps into the current view with a double-click onto a map reference node. A hierarchical layout makes it possible to place different pathways at the desired positions in the graphical network-view and layout each pathway similar to the KEGG Pathway layout.