Rejuvenate Your Cells by Growing New Mitochondria. 1.
Bliznakov EG. Aging, mitochondria, and coenzyme Q(10): the neglected relationship. Biochimie. 1999 Dec;81(12):1131-2. 2. Generate Fresh Mitochondria with PQQ. In 1983, Life Extension® introduced a relatively little-known compound called coenzyme Q10.
Our review of the literature back then had unearthed data confirming its power to boost the health and energy output of the mitochondria. Today, scientists recognize mitochondrial dysfunction as a key biomarker of aging.1-6 To take one instance, researchers have recorded evidence of 50% more mitochondrial damage in the brain cells of humans over 70 compared to middle-aged individuals.7 Mitochondrial dysfunction and death are now definitively linked to the development of virtually all killer diseases of aging, from Alzheimer’s and type 2 diabetes to heart failure.8-11 The good news is that mitochondrial dysfunction can be reversed.12 The scientific literature is now filled with studies documenting the therapeutic power of CoQ10 to thwart degenerative disease by boosting mitochondrial health and bioenergetic (energy-producing) capacity.13-16 PQQ: A Breakthrough in Cellular Anti-Aging.
Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ) was discovered by J.G.
Hauge as the third redox cofactor after nicotinamide and flavin in bacteria (although he hypothesised that it was naphthoquinone).[1] Anthony and Zatman also found the unknown redox cofactor in alcohol dehydrogenase and named it methoxatin.[2] In 1979, Salisbury and colleagues[3] as well as Duine and colleagues[4] extracted this prosthetic group from methanol dehydrogenase of methylotrophs and identified its molecular structure. Adachi and colleagues identified that PQQ was also found in Acetobacter.[5] These enzymes containing PQQ are called quinoproteins. Glucose dehydrogenase, one of the quinoproteins, is used as a glucose sensor.